Sophie Claydon

Control of actin dynamics during cell motility

R. Insall, Simona Buracco, Sophie Claydon, 2019, F1000Research.

The Scar/WAVE complex drives normal actin protrusions without the Arp2/3 complex, but proline-rich domains are required

Peggy I. Paschke, S. Singh, P. Thomason, 2022, bioRxiv.

Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents

M. Drysdale, J. Bower, A. W. Schüttelkopf, 2019, Bioorganic & medicinal chemistry letters.

A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation

S. G. Burgess, Nikki R. Paul, Sophie Claydon, 2024, Open Biology.