Jeffrey J. Lochhead

发表

Atorvastatin therapy lowers circulating cholesterol but not free radical activity in advance of identifiable clinical benefit in the treatment of mild-to-moderate AD.

D. Sparks, Jean E Lopez, D. Connor, 2005, Current Alzheimer Research.

Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain.

T. Davis, P. Ronaldson, Jeffrey J Lochhead, 2012, American journal of physiology. Heart and circulatory physiology.

Oxidative Stress Increases Blood–Brain Barrier Permeability and Induces Alterations in Occludin during Hypoxia–Reoxygenation

T. Davis, Jeffrey J Lochhead, G. McCaffrey, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Water quality has a pronounced effect on cholesterol-induced accumulation of Alzheimer amyloid beta (Abeta) in rabbit brain.

D. Sparks, T. Martin, Jeffrey J Lochhead, 2002, Journal of Alzheimer's disease : JAD.

High-Dose Acetaminophen Alters the Integrity of the Blood–Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats

T. Davis, Junzhi Yang, P. Ronaldson, 2022, Pharmaceutics.

The role of oxidative stress in blood-brain barrier disruption during ischemic stroke: Antioxidants in clinical trials.

P. Ronaldson, Jeffrey J. Lochhead, Thomas P. Davis, 2024, Biochemical pharmacology.

Intranasal delivery of biologics to the central nervous system.

R. Thorne, Jeffrey J Lochhead, Jeffrey J. Lochhead, 2012, Advanced drug delivery reviews.

Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

T. Davis, Junzhi Yang, P. Ronaldson, 2020, Frontiers in Physiology.

Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System

T. Davis, P. Ronaldson, Jeffrey J Lochhead, 2017, The AAPS Journal.

OXIDATIVE STRESS ALTERS BLOOD-BRAIN BARRIER INTEGRITY

Jeffrey J Lochhead, Jeffrey J. Lochhead, 2011 .

Occludin oligomeric assemblies at tight junctions of the blood–brain barrier are altered by hypoxia and reoxygenation stress

T. Davis, Jeffrey J Lochhead, C. L. Willis, 2009, Journal of neurochemistry.

Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results.

Patrick Browne, Lenore J Launer, Jean Lopez, 2005, Archives of neurology.

βIV-spectrin as a stalk cell-intrinsic regulator of VEGF signaling

N. Ellis, G. Mouneimne, Tasmia Ahmed, 2022, Nature Communications.

Cholesterol modifies classical conditioning of the rabbit (Oryctolagus cuniculus) nictitating membrane response.

D. Sparks, B. Schreurs, C. Smith-Bell, 2003, Behavioral neuroscience.

Distribution of insulin in trigeminal nerve and brain after intranasal administration

T. Davis, P. Ronaldson, Jeffrey J Lochhead, 2019, Scientific Reports.

Rapid Transport within Cerebral Perivascular Spaces Underlies Widespread Tracer Distribution in the Brain after Intranasal Administration

R. Thorne, Daniel J Wolak, Robert G Thorne, 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug delivery

V. Ithapu, Vikas Singh, R. Thorne, 2016, Scientific Reports.

Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose‐response, and mechanisms of delivery

R. Thorne, Michelle E Pizzo, Geetika Nehra, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Intranasal Drug Delivery to the Brain

R. Thorne, Jeffrey J Lochhead, Jeffrey J. Lochhead, 2014 .

High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke

T. Davis, P. Ronaldson, Jeffrey J Lochhead, 2023, Cells.