Helinä Kahma

Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions 

P. Neuvonen, M. Niemi, J. Backman, 2018, Drug Metabolism and Disposition.

Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8

J. Backman, M. Neuvonen, R. Totah, 2019, Drug Metabolism and Disposition.

An Automated Cocktail Method for In Vitro Assessment of Direct and Time-Dependent Inhibition of Nine Major Cytochrome P450 Enzymes - Application to Establishing CYP2C8 Inhibitor Selectivity.

M. Niemi, J. Backman, M. Neuvonen, 2021, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The role of OATP transporters in the active uptake of drugs into hepatocytes

Helinä Kahma, 2014 .

Hydroxychloroquine is metabolized by CYP2D6, CYP3A4, and CYP2C8, and inhibits CYP2D6, while its metabolites also inhibit CYP3A in vitro.

M. Niemi, J. Backman, A. Filppula, 2022, Drug metabolism and disposition: the biological fate of chemicals.

Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro

M. Niemi, J. Backman, Anne M. Filppula, 2022, Drug Metabolism and Disposition.