Mamoru Tasaki

Effect of novel PKCθ selective inhibitor AS2521780 on acute rejection in rat and non-human primate models of transplantation.

S. Tsujimoto, J. Hirose, Koji Nakamura, 2015, International immunopharmacology.

Oncolytic vaccinia virus induces a novel phenotype of CD8+ effector T cells characterized by high ICOS expression

Y. Arai, Takafumi Nakamura, Midori Yamashita, 2021, Molecular therapy oncolytics.

Discovery of 2,4-diamino-5-cyanopyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug-drug interactions.

A. Tanaka, N. Chida, Mamoru Tasaki, 2019, Bioorganic & medicinal chemistry.

Optimization of 2,4-diamino-5-fluoropyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug-drug interactions and P-gp liability.

A. Tanaka, S. Nagashima, F. Shirai, 2015, Bioorganic & medicinal chemistry.

Inhibition of antigen-induced airway inflammation and hyperresponsiveness in guinea pigs by a selective antagonist of "chemoattractant receptor homologous molecule expressed on Th2 cells" (CRTH2).

Tadashi Terasaka, S. Tsujimoto, Y. Shimizu, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A novel 2,4-diaminopyrimidine derivative as selective inhibitor of protein kinase C theta prevents allograft rejection in a rat heart transplant model.

A. Tanaka, N. Chida, Mamoru Tasaki, 2018, Bioorganic & medicinal chemistry.

IL-7 coupled with IL-12 increases intratumoral T cell clonality, leading to complete regression of non-immunogenic tumors

Y. Arai, Takafumi Nakamura, Midori Yamashita, 2021, Cancer Immunology, Immunotherapy.

Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade

Y. Arai, T. Kawase, Takafumi Nakamura, 2020, Science Translational Medicine.

Leber's hereditary optic neuropathy with 14484 mutation in Central Java, Indonesia

T. Ishida, A. Soemantri, B. Sudarmanto, 2003, Journal of Human Genetics.

Effect of AS2521780, a novel PKCθ selective inhibitor, on T cell-mediated immunity.

A. Tanaka, Keiko Suzuki, M. Maeda, 2014, European journal of pharmacology.

Abstract 5735: Novel KRAS G12D degrader ASP3082 demonstrates in vivo, dose-dependent KRAS degradation, KRAS pathway inhibition, and antitumor efficacy in multiple KRAS G12D-mutated cancer models

T. Yoshinari, M. Hayakawa, Mamoru Tasaki, 2023, Cancer Research.