Muharrem Akcan

发表

Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro.

M. Ammirati, D. Craik, David A. Price, 2014, Chemistry & biology.

Cyclization of conotoxins to improve their biopharmaceutical properties.

D. Craik, Q. Kaas, N. Daly, 2012, Toxicon : official journal of the International Society on Toxinology.

Transforming conotoxins into cyclotides: Backbone cyclization of P‐superfamily conotoxins

D. Craik, N. Daly, R. Clark, 2015, Biopolymers.

Characterization of a Novel α-Conotoxin from Conus textile That Selectively Targets α6/α3β2β3 Nicotinic Acetylcholine Receptors*

D. Craik, J. McIntosh, Sean B. Christensen, 2012, The Journal of Biological Chemistry.

Cyclotides as templates for peptide GPCR ligand design - discovery of the target receptor of the oxytocic plant peptide kalata B7

Terry J. Smith, D. Craik, S. Wray, 2013 .

Novel α-CTx TxIB Selectively Blocks α 6 / α 3 β 2 β 3 nAChRs 1 Characterization of a Novel α-Conotoxin from Conus textile that Selectively Targets α 6 / α 3 β 2 β 3 Nicotinic Acetylcholine Receptors

D. Craik, J. McIntosh, Sean B. Christensen, 2012 .

Design and modification of frog skin peptide brevinin-1GHa with enhanced antimicrobial activity on Gram-positive bacterial strains

Cemil Kürekci, Muharrem Akcan, Ş. Kara, 2022, Amino Acids.

Synthesis of new thiophene, furan and pyridine substituted 1,2,4,5-oxadiazaboroles

K. Pihlaja, Olli Martiskainen, Elina Siirola, 2008 .

Preparation, characterization and antibacterial activity of Malva Sylvestris L. seed extract containing novel electrospun PVA nanofibers

O. M. Kalfa, Muharrem Akcan, Kubra Turan, 2021 .

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design

Susan Wray, Terry J. Smith, Michael Freissmuth, 2013, Proceedings of the National Academy of Sciences.

Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.

D. Craik, Jonathan M. Harris, K. Rosengren, 2015, The Biochemical journal.

Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1

D. Craik, David John Adams, Q. Kaas, 2015, Scientific Reports.

Conotoxin-based leads in drug design

D. Craik, Muharrem Akcan, 2011 .

Characterization of a novel α-conotoxin TxID from Conus textile that potently blocks rat α3β4 nicotinic acetylcholine receptors.

D. Craik, P. Harvey, J. McIntosh, 2013, Journal of medicinal chemistry.

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy.

Norelle L Daly, David J Craik, James M Olson, 2011, Journal of medicinal chemistry.

Synthesis of cyclic disulfide-rich peptides.

D. Craik, Muharrem Akcan, 2013, Methods in molecular biology.

Enhancing the Stability of Tumor Homing LyP-1 Peptide Using Cyclization and Retro Grafting Strategies

Muharrem Akcan, Elif Ayazoglu Demir, Ş. Kara, 2023, International Journal of Peptide Research and Therapeutics.

Disulfide-rich peptides in drug development

Muharrem Akcan, Ş. Kara, 2020 .

Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic alpha-Conotoxin Vc1.1

David J. Craik, Quentin Kaas, Xinying Jia, 2016 .

Cyclotide-rich fractions containing nanofibers by electrospinning: preparation, characterization and examination of antimicrobial activity

Cemil Kürekci, O. M. Kalfa, Muharrem Akcan, 2022, Turkish journal of chemistry.

The three-dimensional solution structure of mini-M conotoxin BtIIIA reveals a disconnection between disulfide connectivity and peptide fold.

D. Craik, Muharrem Akcan, Ying-Juan Cao, 2013, Bioorganic & medicinal chemistry.

CHAPTER 11:Engineering Venom Peptides to Improve Their Stability and Bioavailability

D. Craik, Muharrem Akcan, 2015 .

Cyclization of conotoxins to improve their biopharmaceutical properties.

D. Craik, Q. Kaas, N. Daly, 2012, Toxicon : official journal of the International Society on Toxinology.

Potentiometric Study of Acid−Base Equilibria of 3,5-Disubstituted 1,2,4,5-Oxadiazaboroles in Nonaqueous Media

Y. Dürüst, Muharrem Akcan, N. Dürüst, 2007 .

Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy.

J. Olson, D. Craik, N. Daly, 2011, Journal of medicinal chemistry.

Characterization of a novel α-conotoxin TxID from Conus textile that potently blocks rat α3β4 nicotinic acetylcholine receptors.

D. Craik, P. Harvey, Sean B. Christensen, 2013, Journal of medicinal chemistry.