Jack W. Stone

Overexpression of RamA, Which Regulates Production of the Multidrug Resistance Efflux Pump AcrAB-TolC, Increases Mutation Rate and Influences Drug Resistance Phenotype

L. Piddock, E. Grimsey, V. Ricci, 2020, Antimicrobial Agents and Chemotherapy.

Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB

Andy M. Lau, Andy M C Lau, P. Ruggerone, 2020, Nature Communications.

Absence, loss-of-function, or inhibition of Escherichia coli AcrB does not increase expression of other efflux pump genes supporting the discovery of AcrB inhibitors as antibiotic adjuvants

Robert L. Marshall, V. Ricci, L. Piddock, 2021, The Journal of antimicrobial chemotherapy.

Perturbed structural dynamics underlie inhibition and altered specificity of the multidrug efflux pump AcrB

Andy M. Lau, Andy M C Lau, P. Ruggerone, 2020, bioRxiv.

Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump

Robert L. Marshall, A. Ivens, P. Ruggerone, 2020, mBio.

Exposure of Escherichia coli to antibiotic-efflux pump inhibitor combinations in a pharmacokinetic model: impact on bacterial clearance and drug resistance.

E. Grimsey, V. Ricci, L. Piddock, 2023, The Journal of antimicrobial chemotherapy.

University of Birmingham Overexpression of RamA, which regulates production of the multidrug resistance efflux pump AcrAB-TolC, increases mutation rate and influences drug resistance phenotype

L. Piddock, E. Grimsey, V. Ricci, 2020 .