A. Chu

发表

Identification and Characterization of a Small Molecule Antagonist of Human VPAC2 Receptor

J. Caldwell, A. Chu, Y. Chen, 2010, Molecular Pharmacology.

Amyloidogenic immunoglobulin light chain kinetic stabilizers comprising a simple urea linker module reveal a novel binding sub-site.

I. Wilson, J. Kelly, G. Morgan, 2022, Bioorganic & medicinal chemistry letters.

Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis (NASH).

I. Sancho-Martinez, P. McNamara, S. Joseph, 2020, Journal of medicinal chemistry.

Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic

H. M. Petrassi, M. Kumar, P. Schultz, 2020, Science.

A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model.

N. Gray, S. Lefebvre, B. Nuesslein-Hildesheim, 2006, Chemistry & biology.

Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator.

N. Gray, S. Lefebvre, Jianwei Che, 2013, ACS medicinal chemistry letters.

Lipid G Protein-coupled Receptor Ligand Identification Using β-Arrestin PathHunter™ Assay

J. Caldwell, D. Nguyen, H. Yin, 2009, Journal of Biological Chemistry.

Identification of Cathepsin B as a Mediator of Neuronal Death Induced by Aβ-activated Microglial Cells Using a Functional Genomics Approach*

L. Gan, L. Patthy, D. Chin, 2004, Journal of Biological Chemistry.

Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design.

H. M. Petrassi, I. Wilson, J. Kelly, 2021, Journal of medicinal chemistry.