J. Min

发表

Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors.

B. Katzenellenbogen, J. Katzenellenbogen, K. Nettles, 2017, Cancer research.

Dual-mechanism estrogen receptor inhibitors

B. Katzenellenbogen, J. Nwachukwu, S. Srinivasan, 2021, Proceedings of the National Academy of Sciences.

Peroxiredoxin II Is an Antioxidant Enzyme That Negatively Regulates Collagen-stimulated Platelet Function*

Dae-Yeul Yu, J. Y. Baek, J. Jang, 2015, The Journal of Biological Chemistry.

Resveratrol inhibits collagen-induced platelet stimulation through suppressing NADPH oxidase and oxidative inactivation of SH2 domain-containing protein tyrosine phosphatase-2.

J. Y. Baek, J. Jang, Su Bin Wang, 2015, Free radical biology & medicine.

Thiophene-core estrogen receptor ligands having superagonist activity.

J. Nwachukwu, S. Srinivasan, J. Katzenellenbogen, 2013, Journal of medicinal chemistry.

Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells.

B. Katzenellenbogen, S. Srinivasan, J. Katzenellenbogen, 2017, Journal of medicinal chemistry.

Kaempferol suppresses collagen-induced platelet activation by inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation.

J. Y. Baek, J. Jang, Su Bin Wang, 2015, Free radical biology & medicine.

New Class of Selective Estrogen Receptor Degraders (SERDs): Expanding the Toolbox of PROTAC Degrons.

Jian Min, Abhishek Sharma, Sarat Chandarlapaty, 2018, ACS medicinal chemistry letters.

Reactive oxygen species play a critical role in collagen-induced platelet activation via SHP-2 oxidation.

Y. Ho, G. Oh, S. J. Park, 2014, Antioxidants & redox signaling.

Identification and structure-activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2.2.1]hept-2-ene-7-oxide.

J. Nwachukwu, Valerie Cavett, J. Katzenellenbogen, 2012, Journal of medicinal chemistry.

Predictive features of ligand‐specific signaling through the estrogen receptor

O. Elemento, J. Nwachukwu, S. Srinivasan, 2016, Molecular systems biology.

Development of Selective Estrogen Receptor Modulator (SERM)‐Like Activity Through an Indirect Mechanism of Estrogen Receptor Antagonism: Defining the Binding Mode of 7‐Oxabicyclo[2.2.1]hept‐5‐ene Scaffold Core Ligands

J. Nwachukwu, S. Srinivasan, Valerie Cavett, 2012, ChemMedChem.

Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain.

B. Katzenellenbogen, S. Chandarlapaty, J. Katzenellenbogen, 2018, ACS chemical biology.

Dual-mechanism estrogen receptor inhibitors expand the repertoire of anti-hormone therapy for breast cancer

B. Katzenellenbogen, J. Nwachukwu, S. Srinivasan, 2020, bioRxiv.

Full Antagonism of the Estrogen Receptor without a Prototypical Ligand Side Chain

J. Frasor, B. Katzenellenbogen, J. Nwachukwu, 2016, Nature Chemical Biology.

Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain.

J. Frasor, B. Katzenellenbogen, J. Nwachukwu, 2017, Nature chemical biology.

Asymmetric Allostery in Estrogen Receptor-α Homodimers Drives Responses to the Ensemble of Estrogens in the Hormonal Milieu

B. Katzenellenbogen, J. Nwachukwu, J. Katzenellenbogen, 2024, bioRxiv.