X. Kou

发表

Genome-wide analysis of pleiotropic and functional variants across three age-related ocular disorders

Maohui Luo, Hang Yang, J. Wang, 2022, medRxiv.

Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells.

K. Rudolph, Shaorong Gao, Z. Ju, 2014, Cell stem cell.

Unique Patterns of H3K4me3 and H3K27me3 in 2-Cell-like Embryonic Stem Cells

Yanping Zhang, Shaorong Gao, Yawei Gao, 2021, Stem cell reports.

FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development

Chuan He, Ziyang Hao, Xuekun Li, 2022, Science.

Inhibition of Aberrant DNA Re-methylation Improves Post-implantation Development of Somatic Cell Nuclear Transfer Embryos.

Shaorong Gao, Chenfei Wang, Wenqiang Liu, 2018, Cell stem cell.

Altered sperm tsRNAs in aged male contribute to anxiety‐like behavior in offspring

Shaorong Gao, Wenqiang Liu, Jiayu Chen, 2021, Aging cell.

Identification of key factors conquering developmental arrest of somatic cell cloned embryos by combining embryo biopsy and single-cell sequencing

W. Liu, Hong Wang, Su Wang, 2016, Cell Discovery.

Aberrant nucleosome organization in mouse SCNT embryos revealed by ULI-MNase-seq

Hong Wang, Shaorong Gao, Yanhong Zhao, 2022, Stem cell reports.

Naïve Induced Pluripotent Stem Cells Generated From β‐Thalassemia Fibroblasts Allow Efficient Gene Correction With CRISPR/Cas9

Hong Wang, Cizhong Jiang, Shaorong Gao, 2016, Stem cells translational medicine.

Asymmetric reprogramming capacity of parental pronuclei in mouse zygotes.

Hong Wang, Shaorong Gao, Wenqiang Liu, 2014, Cell reports.

Mettl14-driven senescence-associated secretory phenotype facilitates somatic cell reprogramming

Hong Wang, Shaorong Gao, You Wu, 2022, Stem cell reports.

Genome transfer for the prevention of female infertility caused by maternal gene mutation.

Cizhong Jiang, Shaorong Gao, Wenqiang Liu, 2020, Journal of genetics and genomics = Yi chuan xue bao.

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin–NFATc3–Etv2 pathway

Hong Wang, Shaorong Gao, Wenqiang Liu, 2017, Journal of molecular cell biology.

Hierarchical Oct4 Binding in Concert with Primed Epigenetic Rearrangements during Somatic Cell Reprogramming.

Hong Wang, Cizhong Jiang, Shaorong Gao, 2016, Cell reports.

Allelic reprogramming of the histone modification H3K4me3 in early mammalian development

Y. Zhang, Wei Xie, Qianhua Xu, 2016, Nature.

Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming.

T. Cai, Shaorong Gao, Wenqiang Liu, 2013, Cell stem cell.

Reprogramming of H3K9me3-dependent heterochromatin during mammalian embryo development

Chenfei Wang, Yawei Gao, Xiaochen Kou, 2018, Nature Cell Biology.

Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation

Hong Wang, Bo Peng, Shaorong Gao, 2017, Stem cell reports.

Unique features of mutations revealed by sequentially reprogrammed induced pluripotent stem cells

Jianhui Tian, Shuai Gao, Jun Cai, 2015, Nature Communications.

Xist Repression Shows Time‐Dependent Effects on the Reprogramming of Female Somatic Cells to Induced Pluripotent Stem Cells

Hong Wang, Shaorong Gao, Yanhong Zhao, 2014, Stem cells.

Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress

Yanping Zhang, Shaorong Gao, Yanhong Zhao, 2021, Cell proliferation.

Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos

Yong Zhang, Shaorong Gao, Chenfei Wang, 2016, Nature.

BMP4 preserves the developmental potential of mESCs through Ube2s- and Chmp4b-mediated chromosomal stability safeguarding

Hong Wang, Cizhong Jiang, Shaorong Gao, 2022, Protein & Cell.

Reduced Self-Diploidization and Improved Survival of Semi-cloned Mice Produced from Androgenetic Haploid Embryonic Stem Cells through Overexpression of Dnmt3b

Cizhong Jiang, Shaorong Gao, Wenqiang Liu, 2018, Stem cell reports.

Nuclear m6A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos

Shaorong Gao, Wenqiang Liu, Yawei Gao, 2021, Protein & Cell.

Nucleosome organizations in induced pluripotent stem cells reprogrammed from somatic cells belonging to three different germ layers

Hong Wang, Weisheng Zheng, Shuai Gao, 2014, BMC Biology.

High-throughput sequencing reveals the disruption of methylation of imprinted gene in induced pluripotent stem cells

T. Cai, Shaorong Gao, T. Cheng, 2013, Cell Research.

N6-methyladenosine regulates maternal RNA maintenance in oocytes and timely RNA decay during mouse maternal-to-zygotic transition

Hong Wang, Shaorong Gao, C. Yi, 2022, Nature Cell Biology.

The dual role of N6-methyladenosine on mouse maternal RNAs and 2-cell specific RNAs revealed by ULI-MeRIP sequencing

Shaorong Gao, C. Yi, Meiling Zhang, 2021, bioRxiv.

Nuclear m6A reader Ythdc1 regulates the scaffold function of LINE1 in mouse ESCs

Shaorong Gao, Wenqiang Liu, Yawei Gao, 2021, bioRxiv.

Nuclear Exosome Targeting Complex Core Factor Zcchc8 Regulates the Degradation of LINE1 RNA in Early Embryos and Embryonic Stem Cells.

Shaorong Gao, Wenqiang Liu, Yawei Gao, 2019, Cell reports.

Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells.

Hong Wang, Yanping Zhang, Shaorong Gao, 2020, Cell stem cell.

Dynamic nucleosome organization after fertilization reveals regulatory factors for mouse zygotic genome activation

Shaorong Gao, Chenfei Wang, Yawei Gao, 2022, Cell Research.

Protein Expression Landscape of Mouse Embryos during Pre-implantation Development.

Hong Wang, She Chen, Lin Li, 2017, Cell reports.

Maternal Sall4 Is Indispensable for Epigenetic Maturation of Mouse Oocytes*

Hong Wang, Shaorong Gao, Hailin Wang, 2016, The Journal of Biological Chemistry.

Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos

Hong Wang, Cizhong Jiang, Shaorong Gao, 2020, Nature Communications.

Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer

W. Tan, D. Lin, F. He, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Paradoxical role of autophagy in the dysplastic and tumor-forming stages of hepatocarcinoma development in rats

Y. Zhou, Ying-ying Jing, K. Sun, 2013, Cell Death and Disease.

Precise temporal regulation of Dux is important for embryo development

Yanping Zhang, Shaorong Gao, Yixuan Wang, 2019, Cell Research.

Jump-seq: Genome-Wide Capture and Amplification of 5-Hydroxymethylcytosine Sites.

Yuwen Liu, Lulu Hu, Chuan He, 2019, Journal of the American Chemical Society.

LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei

Shaorong Gao, Jiang Zhu, Hong Wang, 2023, Nature Communications.

Differential Transcriptomes and Methylomes of Trophoblast Stem Cells From Naturally-Fertilized and Somatic Cell Nuclear-Transferred Embryos

Cizhong Jiang, Shaorong Gao, Wenqiang Liu, 2021, Frontiers in Cell and Developmental Biology.

Dosage effects of ZP2 and ZP3 heterozygous mutations cause human infertility

Shaorong Gao, Wenqiang Liu, Jiqing Yin, 2017, Human Genetics.

Dux-Mediated Corrections of Aberrant H3K9ac during 2-Cell Genome Activation Optimize Efficiency of Somatic Cell Nuclear Transfer.

Cizhong Jiang, Shaorong Gao, Wenqiang Liu, 2020, Cell stem cell.

Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue causes placental defects and implantation failure in mouse IVF embryos.

Hong Wang, Cizhong Jiang, Shaorong Gao, 2022, Cell reports.

Reprogramming of H3K9me3-dependent heterochromatin during mammalian embryo development

Hong Wang, Shaorong Gao, Chenfei Wang, 2018, Nature Cell Biology.

Farrerol directly activates the deubiqutinase UCHL3 to promote DNA repair and reprogramming when mediated by somatic cell nuclear transfer

Hong Wang, Shaorong Gao, Jiaqing Yang, 2023, Nature Communications.

Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos

Cizhong Jiang, Shaorong Gao, Yanhong Zhao, 2020, Nature Communications.

Melatonin supplementation in the culture medium rescues impaired glucose metabolism in IVF mice offspring

Shaorong Gao, Wenqiang Liu, Xiaochen Kou, 2021, Journal of pineal research.

Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation

Shaorong Gao, Wenqiang Liu, Xiaochen Kou, 2020, Nature Communications.

Bilineage embryo-like structure from EPS cells can produce live mice with tetraploid trophectoderm

Hong Wang, Shaorong Gao, Wenqiang Liu, 2022, Protein & cell.

Naïve Induced Pluripotent Stem Cells Generated From β-Thalassemia Fibroblasts Allow Efficient Gene Correction With CRISPR/Cas9

Hong Wang, Cizhong Jiang, Shaorong Gao, 2015, Stem cells translational medicine.

Unreprogrammed H3K9me3 prevents minor zygotic genome activation and lineage commitment in SCNT embryos

Hong Wang, Cizhong Jiang, Shaorong Gao, 2023, Nature communications.

High throughput sequencing identifies an imprinted gene, Grb10, associated with the pluripotency state in nuclear transfer embryonic stem cells

Hong Wang, T. Cai, Shaorong Gao, 2017, Oncotarget.

Inhibition of Wnt activity improves peri-implantation development of somatic cell nuclear transfer embryos

Hong Wang, Shaorong Gao, Caihong Zheng, 2023, National Science Review.

Enhancement of Xrcc1-mediated base excision repair improves the genetic stability and pluripotency of iPSCs.

Hong Wang, Shaorong Gao, Zhu Xu, 2022, Science Bulletin.

CRISPR/Cas9-mediated genome engineering of the ferret

Hong Wang, Xiaoqun Wang, Z. Zuo, 2015, Cell Research.

Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells.

K. Rudolph, Shaorong Gao, Z. Ju, 2014, Cell stem cell.

Enhanced Rejuvenation in Induced Pluripotent Stem Cell-Derived Neurons Compared with Directly Converted Neurons from an Aged Mouse.

Hong Wang, Jiao Jiao, Shaorong Gao, 2015, Stem cells and development.

Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice

Yanhong Zhao, Hong Wang, X. Kou, 2024, Stem cell research & therapy.

Pivotal role for long noncoding RNAs in zygotic genome activation in mice.

Yanhong Zhao, Hong Wang, X. Kou, 2024, Science China. Life sciences.

Loss of Tet hydroxymethylase activity causes mouse embryonic stem cell differentiation bias and developmental defects.

Yanhong Zhao, Hong Wang, Zhibin Qiao, 2024, Science China. Life sciences.

Male-pronuclei-specific granulin facilitates somatic cells reprogramming via mitigating excessive cell proliferation and enhancing lysosomal function.

Yanhong Zhao, X. Kou, Jiatong Sun, 2024, Journal of cellular physiology.