Paul D. Robbins

发表

Chronic HIV Infection and Aging: Application of a Geroscience-Guided Approach

G. Kuchel, F. Palella, A. Landay, 2022, Journal of acquired immune deficiency syndromes.

Novel small molecule inhibition of IKK/NF‐κB activation reduces markers of senescence and improves healthspan in mouse models of aging

N. LeBrasseur, Y. Suh, J. Huard, 2021, Aging cell.

Fisetin for COVID‐19 in skilled nursing facilities: Senolytic trials in the COVID era

D. Kiel, S. Kritchevsky, L. Lipsitz, 2021, Journal of the American Geriatrics Society.

Adenovirus‐Mediated Gene Transfer to Nucleus Pulposus Cells: Implications for the Treatment of Intervertebral Disc Degeneration

James D. Kang, L. Gilbertson, K. Nishida, 1998, Spine.

Cellular senescence: a key therapeutic target in aging and diseases

M. Yousefzadeh, L. Niedernhofer, Yi Zhu, 2022, The Journal of clinical investigation.

Interleukin‐12 and B7.1 co‐stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumors

L. Zitvogel, R. Schreiber, M. Lotze, 1996, European journal of immunology.

Targeted clearance of p21‐ but not p16‐positive senescent cells prevents radiation‐induced osteoporosis and increased marrow adiposity

N. LeBrasseur, S. Khosla, J. Farr, 2022, Aging cell.

The Clinical Potential of Senolytic Drugs

L. Niedernhofer, J. Kirkland, T. Tchkonia, 2017, Journal of the American Geriatrics Society.

Cytokine Gene Therapy of Cancer Using Interleukin‐12: Murine and Clinical Trials

L. Zitvogel, T. Whiteside, H. Tahara, 1996, Annals of the New York Academy of Sciences.

Rb Inhibits the Intrinsic Kinase Activity of TATA-Binding Protein-Associated Factor TAFII250

P. Robbins, J. Siegert, Paul D. Robbins, 1999, Molecular and Cellular Biology.

Dendritic cell‐based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti‐melanoma immunity

A. Enk, A. Gambotto, A. Deleo, 1999, The journal of gene medicine.

Exosomes from IDO+ DC are therapeutic in CIA and DTH disease models

Seonhee Kim, P. Robbins, N. Bianco, 2012 .

Orthopaedic Gene Therapy: Twenty-Five Years On.

S. Ghivizzani, P. Robbins, C. Evans, 2021, JBJS reviews.

Recombinant Adenovirus Induces Maturation of Dendritic Cells via an NF-κB-Dependent Pathway

A. Thomson, A. Zahorchak, A. Morelli, 2000, Journal of Virology.

Heterochronic parabiosis: a valuable tool to investigate cellular senescence and other hallmarks of aging

M. Yousefzadeh, D. Huffman, P. Robbins, 2022, Aging.

COVID-19 and cellular senescence

Soyoung Lee, C. Schmitt, L. Niedernhofer, 2022, Nature reviews. Immunology.

Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells

Y. Li, J. Huard, G. Rodney, 2022, Journal of cachexia, sarcopenia and muscle.

Express IL-4 Dendritic Cells Genetically Modified to Models with Exosomes Derived from Effective Treatment of Inflammatory Disease

A. Morelli, Seonhee Kim, P. Robbins, 2007 .

Genetic engineering of dendritic cells to express immunosuppressive molecules (viral IL‐10, TGF‐β, and CTLA4Ig)

A. Gambotto, A. Thomson, S. Qian, 1999, Journal of leukocyte biology.

IFN-g-Inducing Factor/IL-18 Administration Mediates IFN- g- and IL-12-Independent Antitumor Effects

H. Okamura, M. Kurimoto, M. Lotze, 1998 .

Senolytic elimination of senescent macrophages restores muscle stem cell function in severely dystrophic muscle

J. Huard, Zewei Sun, X. Mu, 2022, Aging.

Targeting Cellular Senescence with Senotherapeutics: Development of New Approaches for Skin Care

L. Niedernhofer, P. Robbins, Louise E. Pitcher, 2021, Plastic and reconstructive surgery.

Effect in Mice Cancer-Induced Apoptosis and Antitumor Increases Their Resistance to Prostate L Transduction of Dendritic Cells with Bcl-x

G. Shurin, M. Shurin, G. Pirtskhalaishvili, 2022 .

Cellular Senescence in Obesity and Associated Complications: a New Therapeutic Target

D. Bernlohr, L. Niedernhofer, Akilavalli Narasimhan, 2022, Current Diabetes Reports.

Differential effects of IL‐12 on the generation of alloreactive CTL mediated by murine and human dendritic cells: a critical role for nitric oxide

M. Lotze, S. Sone, Y. Nishioka, 2003, Journal of leukocyte biology.

Increased function and survival of IL‐15‐transduced human dendritic cells are mediated by up‐regulation of IL‐15Rα and Bcl‐2

A. Gambotto, Z. Yurkovetsky, G. Shurin, 2002, Journal of leukocyte biology.

Comparative analysis of antitumor activity of CD40L, RANKL, and 4‐1BBL in vivo following intratumoral administration of viral vectors or transduced dendritic cells

Z. Yurkovetsky, A. Schuh, G. Shurin, 2006, The journal of gene medicine.

SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3

F. Kirchhoff, D. B. Allison, L. Niedernhofer, 2021, Aging.

B7‐1/2, but not PD‐L1/2 molecules, are required on IL‐10‐treated tolerogenic DC and DC‐derived exosomes for in vivo function

Loise M. Francisco, A. Sharpe, Seonhee Kim, 2009, European journal of immunology.

Transfer of Genes to Chondrocytic Cells of the Lumbar Spine: Proposal for a Treatment Strategy of Spinal Disorders by Local Gene Therapy

P. Wehling, K. Schulitz, P. Robbins, 1997, Spine.

Effective Treatment of Established Murine Collagen-Induced Arthritis by Systemic Administration of Dendritic Cells Genetically Modified to Express IL-41

S. Ghivizzani, Seonhee Kim, Sunyoung Kim, 2001, The Journal of Immunology.

Intra‐articular gene delivery and expression of interleukin‐1Ra mediated by self‐complementary adeno‐associated virus

D. Nickerson, S. Ghivizzani, P. Levings, 2009, The journal of gene medicine.

Construction of Retroviral Vectors with Improved Safety, Gene Expression, and Versatility

C. An, Sunyoung Kim, Seonhee Kim, 1998, Journal of Virology.

NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health.

Philip D. Blood, Ellen M. Quardokus, Matthew A. Wyczalkowski, 2022, Nature aging.

Gene Therapy in Sports Medicine

P. Robbins, F. Fu, C. Evans, 1998, Sports medicine.