H. Shikama

发表

Novel muteins of human tumor necrosis factor with potent antitumor activity and less lethal toxicity in mice

K. Takeda, K. Miyata, M. Kato, 1995, International journal of cancer.

A novel MPL point mutation resulting in thrombopoietin-independent activation

S. Sassa, O. Inagaki, M. Abe, 2002, Leukemia.

Development of stabilized fuzapladib solution for injection: forced degradation study and pharmacokinetic evaluation

S. Onoue, Hideyuki Sato, Kohei Yamada, 2022, Pharmaceutical development and technology.

Nanocrystal solid dispersion of fuzapladib free acid with improved oral bioavailability

S. Onoue, Hideyuki Sato, Kohei Yamada, 2022, Biopharmaceutics & drug disposition.

Efficacy of the inflammatory cell infiltration inhibitor IS-741 on colitis induced by dextran sulfate sodium in the rat.

S. Yotsuya, H. Shikama, M. Imamura, 2001, Japanese journal of pharmacology.

Effect of IS-741 on cell adhesion between human umbilical vein endothelial cells and HL-60 cells.

M. Kato, S. Satake, S. Yotsuya, 1999, Biological and Pharmaceutical Bulletin.

Species differences in the biopharmaceutical properties of fuzapladib sodium monohydrate in rats, cats, and dogs

S. Onoue, Hideyuki Sato, Kohei Yamada, 2022, Pharmacy & Pharmacology International Journal.

Inhibitory effects of the new anti‐inflammatory agent, IS‐741, on spontaneous colitis in HLA‐B27/β2‐microglobulin transgenic rats

A. Andoh, Y. Fujiyama, T. Bamba, 2002, Journal of gastroenterology and hepatology.

Novel Mutein of Tumor Necrosis Factor α (F4614) with Reduced Hypotensive Effect

K. Miyata, K. Kuroda, Masanari Kato, 1995 .

Overcoming the metastasis-enhancing potential of human tumor necrosis factor alpha by introducing the cell-adhesive Arg-Gly-Asp sequence.

K. Miyata, M. Kato, K. Kuroda, 1995, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

A Novel Synthetic Anti-Acute Pancreatitis Agent, IS-741

I. Nakano, Y. Koga, H. Takada, 1999, Digestion.

Biochemistry Research Laboratory, and Environmental Sciences Laboratory, Central

K. Miyata, K. Kuroda, Masanari Kato, 1994 .

A novel Mutein of TNFα Containing the Arg-Gly-Asp Sequence Shows Reduced Toxicity in Intestine

K. Miyata, M. Kato, K. Kuroda, 1994, Mediators of inflammation.

Close correlation between restriction fragment length polymorphism of the L-MYC gene and metastasis of human lung cancer to the lymph nodes and other organs.

T. Naruke, K. Kawashima, K. Okabayashi, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Novel mutein of tumor necrosis factor alpha (F4614) with reduced hypotensive effect.

K. Miyata, M. Kato, K. Kuroda, 1995, Journal of Interferon and Cytokine Research.

Suppressive effects of a new anti-inflammatory agent, IS-741, on dextran sulfate sodium-induced experimental colitis in rats.

A. Andoh, Y. Fujiyama, Y. Araki, 2002, International journal of molecular medicine.

Decreased Gene Expression of Testicular Cell-Specific Proteins in Cadmium-Induced Acute Testicular Toxicity

K. Nemoto, Masaki Yamada, M. Degawa, 2009 .

Antisecretory and antiulcer effects of YM020, a new H+,K(+)-ATPase inhibitor, in rats and dogs.

A. Nishida, K. Miyata, M. Ohta, 1995, Japanese journal of pharmacology.

A YIGSR-containing novel mutein without the detrimental effect of human TNF-α of enhancing experimental pulmonary metastasis

K. Miyata, K. Yamaguchi, M. Kato, 1992, Clinical & Experimental Metastasis.

Polylysine-Containing Hydrogel Formulation of Fuzapladib, Inhibitor of Leukocyte-Function Associated Antigen-1 (LFA-1) Activation, for Sustained Release

S. Onoue, Hideyuki Sato, Kohei Yamada, 2023, Molecules.