D. Combs

发表

Synthesis and renal vasodilator activity of substituted [4-alkyl(aryl)quinazolin-2-one-1-yl]alkanoic acids

R. Falotico, R. Kanojia, R. Russell, 1992 .

Benzoxazinones as PPARγ agonists. Part 1: SAR of three aromatic regions

I. Turchi, T. Burris, Jun Z. Xu, 2003 .

Aminoimidazoles as bioisosteres of acylguanidines: novel, potent, selective and orally bioavailable inhibitors of the sodium hydrogen exchanger isoform-1.

M. Kirby, Saleem Ahmad, G. Chandrasena, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 1,3-disubstituted cyclohexylmethyl urea and amide derivatives as non-peptidic motilin receptor antagonists.

R. Rivero, J. Gunnet, K. Demarest, 2006, Bioorganic & medicinal chemistry letters.

Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase.

J. Macor, N. Murugesan, Z. Gu, 2005, Bioorganic & medicinal chemistry letters.

Nonsteroidal progesterone receptor ligands. 1. 3-Aryl-1-benzoyl-1,4,5,6-tetrahydropyridazines.

D. Combs, K. Reese, A. Phillips, 1995, Journal of medicinal chemistry.

Nonsteroidal progesterone receptor ligands. 2. High-affinity ligands with selectivity for bone cell progesterone receptors.

L. Cornelius, J. Gunnet, K. Demarest, 1995, Journal of medicinal chemistry.

6-Benzoxazinylpyridazin-3-ones: potent, long-acting positive inotrope and peripheral vasodilator agents.

R. Falotico, D. Klaubert, A. Tobia, 1990, Journal of medicinal chemistry.

Parallel synthesis of 2-alkoxy and 2-acyloxyphenylpropyl amides and amines using dihydrocoumarins as versatile synthons. Application of a novel resin quench-capture method

J. Bussolari, D. Combs, Diana C. Rehborn, 1999 .

Discovery of selective imidazole-based inhibitors of mammalian 15-lipoxygenase: highly potent against human enzyme within a cellular environment.

C. S. Madsen, Shaobin Zhuang, J. Robl, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and cardiotonic activity of 2,9-dihydro-6-(5-methyl-3-oxo-2,3,4,5-tetrahydropyridazin-6-yl)pyrazolo[4,3-b][1,4]benzoxazine

D. Combs, 1993 .

Chapter 19. Male Contraception

D. Combs, 1997 .

Synthesis and cardiotonic activity of a series of substituted 4-alkyl-2(1H)-quinazolinones.

R. Kanojia, S. Bell, M. Appollina, 1987, Journal of medicinal chemistry.

Total synthesis of the chartreusin aglycon

F. Hauser, D. Combs, 1980 .

Benzoxazinones as PPARgamma agonists. 2. SAR of the amide substituent and in vivo results in a type 2 diabetes model.

T. Burris, K. Demarest, P. Rybczynski, 2004, Journal of medicinal chemistry.

A Convenient Synthesis of Mono- and Polyhalogenated Benzocyclanones

L. Cornelius, D. Combs, 1994 .

7-Amino-5-(methylamino)heptanoic acid: a potential putrescine hapten

F. Hauser, G. Daves, D. Combs, 1981 .

Aklavin-type anthracyclinones: brief, regioispecific syntheses of tetracyclic intermediates

F. Hauser, D. Combs, S. Prasanna, 1983 .

Heteroatom analogues of bemoradan: chemistry and cardiotonic activity of 1,4-benzothiazinylpyridazinones.

R. Falotico, J. B. Moore, D. Combs, 1992, Journal of medicinal chemistry.

Heteroatom Analogues of Bemoradan: Chemistry and Cardiotonic Activity of 1,4‐Benzothiazinylpyridazinones.

R. Falotico, D. Combs, J. P. Demers, 1992 .

Nonsteroidal progesterone receptor ligands with unprecedented receptor selectivity

S. Palmer, Muh-Tsann Lai, G. Allan, 2000, The Journal of Steroid Biochemistry and Molecular Biology.

Pyrazole-based sulfonamide and sulfamides as potent inhibitors of mammalian 15-lipoxygenase.

Saleem Ahmad, C. S. Madsen, Xing Chen, 2011, Bioorganic & medicinal chemistry letters.

Review Oncologic, Endocrine & Metabolic: Recent developments in aromatase inhibitors

D. Combs, 1995 .

gamma-Aminobutyrate-A receptor modulation by 3-aryl-1-(arylsulfonyl)- 1,4,5,6-tetrahydropyridazines.

R. Shank, B. Dubinsky, P. Rybczynski, 1999, Journal of medicinal chemistry.

Induction of a novel conformation in the progesterone receptor by ZK299 involves a defined region of the carboxyl-terminal tail.

S. Palmer, G. Allan, C. Campen, 1996, Molecular Endocrinology.

Phosphoryl chloride induced ring contraction of 1,4-benzodiazepinones to chloromethylquinazolines

S. Bell, J. Press, D. Combs, 1986 .

Pyrazole-based sulfonamide and sulfamides as potent inhibitors of mammalian 15-lipoxygenase.

Saleem Ahmad, C. S. Madsen, Xing Chen, 2011, Bioorganic & medicinal chemistry letters.