Nobukazu Kakui

发表

Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.

M. Ishikawa, Fumikazu Yokoyama, R. Shinei, 2010, Journal of medicinal chemistry.

Critical Role of the Automodification of Poly(ADP-ribose) Polymerase-1 in Nuclear Factor-κB-dependent Gene Expression in Primary Cultured Mouse Glial Cells*

H. Nakajima, H. Nagaso, M. Ishikawa, 2004, Journal of Biological Chemistry.

Synthesis and structure-activity relationships of N-aryl-piperidine derivatives as potent (partial) agonists for human histamine H3 receptor.

M. Ishikawa, Fumikazu Yokoyama, T. Furuuchi, 2010, Bioorganic & medicinal chemistry.

Direct evidence that stimulation of neuropeptide Y Y5 receptor activates hypothalamo-pituitary-adrenal axis in conscious rats via both corticotropin-releasing factor- and arginine vasopressin-dependent pathway.

Koichi Kitamura, Nobukazu Kakui, 2007, Endocrinology.

The selective serotonin reuptake inhibitor fluvoxamine suppresses post-feeding hyperactivity induced by food restriction in rats

Fumikazu Yokoyama, T. Imanishi, K. Onozawa, 2007, Pharmacology Biochemistry and Behavior.

Pharmacological Characterization and Feeding-Suppressive Property of FMS586 [3-(5,6,7,8-Tetrahydro-9-isopropyl-carbazol-3-yl)-1-methyl-1-(2-pyridin-4-yl-ethyl)-urea Hydrochloride], a Novel, Selective, and Orally Active Antagonist for Neuropeptide Y Y5 Receptor

J. Tanaka, K. Asai, Makoto Suzuki, 2006, Journal of Pharmacology and Experimental Therapeutics.

Anxiolytic-like profiles of histamine H3 receptor agonists in animal models of anxiety: a comparative study with antidepressants and benzodiazepine anxiolytic

M. Ishikawa, Fumikazu Yokoyama, R. Shinei, 2009, Psychopharmacology.

EF6265, a novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor, protects against sepsis-induced organ dysfunction in rats*

H. Ishii, H. Iida, Y. Muto, 2009, Critical care medicine.

A Newly Synthesized Poly(ADP-Ribose) Polymerase Inhibitor, DR2313 [2-Methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: Pharmacological Profiles, Neuroprotective Effects, and Therapeutic Time Window in Cerebral Ischemia in Rats

H. Nakajima, M. Ishikawa, Nobukazu Kakui, 2005, Journal of Pharmacology and Experimental Therapeutics.

Investigation of the histamine H3 receptor binding site. Design and synthesis of hybrid agonists with a lipophilic side chain.

T. Kudo, M. Ishikawa, Fumikazu Yokoyama, 2010, Journal of medicinal chemistry.

Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and α1-adrenergic receptor

Takeshi Inoue, T. Koyama, Fumikazu Yokoyama, 2009, Pharmacology Biochemistry and Behavior.

Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and α1-adrenergic receptor

Takeshi Inoue, T. Koyama, Fumikazu Yokoyama, 2009, Pharmacology Biochemistry and Behavior.

EF6265, a novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor, protects against sepsis-induced organ dysfunction in rats*

H. Ishii, H. Iida, Y. Muto, 2009, Critical care medicine.