Nicoletta Brindani

发表

Phenyl-γ-valerolactones, flavan-3-ol colonic metabolites, protect brown adipocytes from oxidative stress without affecting their differentiation or function.

M. Vacca, A. Vidal-Puig, S. Rodriguez-Cuenca, 2017, Molecular nutrition & food research.

Quercetin and luteolin are single-digit micromolar inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase

A. Armirotti, M. De Vivo, G. Ottonello, 2021, Scientific Reports.

5-(Hydroxyphenyl)-γ-Valerolactone-Sulfate, a Key Microbial Metabolite of Flavan-3-ols, Is Able to Reach the Brain: Evidence from Different in Silico, In Vitro and In Vivo Experimental Models

C. Davis, D. Angelino, K. Kim, 2019, Nutrients.

5-(3′,4′-Dihydroxyphenyl)-γ-valerolactone and its sulphate conjugates, representative circulating metabolites of flavan-3-ols, exhibit anti-adhesive activity against uropathogenic Escherichia coli in bladder epithelial cells

A. Esteban-Fernández, B. Bartolomé, M. Moreno-Arribas, 2017 .

Catalytic, Enantioselective Vinylogous Mukaiyama Aldol Reaction of Furan‐Based Dienoxy Silanes: A Chemodivergent Approach to γ‐Valerolactone Flavan‐3‐ol Metabolites and δ‐Lactone Analogues

F. Brighenti, P. Mena, C. Curti, 2015 .

Bioavailability of Black Tea Theaflavins: Absorption, Metabolism, and Colonic Catabolism.

M. Lean, A. Crozier, D. Del Rio, 2017, Journal of agricultural and food chemistry.

Flavonoid-Derived Human Phenyl-γ-Valerolactone Metabolites Selectively Detoxify Amyloid-β Oligomers and Prevent Memory Impairment in a Mouse Model of Alzheimer's Disease.

G. Forloni, S. Ottonello, V. Franceschi, 2020, Molecular nutrition & food research.

Exploiting the Distal Reactivity of Indolyl Methylenemalononitriles: An Asymmetric Organocatalyzed [4+2] Cycloaddition with Enals Enables the Assembly of Elusive Dihydrocarbazoles.

C. Curti, L. Pinna, F. Zanardi, 2016, Chemistry.

Pushing the boundaries of vinylogous reactivity: catalytic enantioselective mukaiyama aldol reactions of highly unsaturated 2-silyloxyindoles.

M. Mor, C. Curti, L. Battistini, 2015, Chemistry.

Organocatalytic, Asymmetric Eliminative [4+2] Cycloaddition of Allylidene Malononitriles with Enals: Rapid Entry to Cyclohexadiene-Embedding Linear and Angular Polycycles.

C. Curti, L. Pinna, L. Battistini, 2015, Angewandte Chemie.

Phenyl-γ-valerolactones and phenylvaleric acids, the main colonic metabolites of flavan-3-ols: synthesis, analysis, bioavailability, and bioactivity.

D. Angelino, M. Clifford, A. Crozier, 2019, Natural product reports.

Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer

A. Ganesan, R. Bertorelli, R. Edwards, 2021, bioRxiv.

Identification, Structure–Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators

R. Bertorelli, L. Goldoni, N. Pedemonte, 2020, Journal of medicinal chemistry.

Computer-aided identification, synthesis, and biological evaluation of DNA polymerase η inhibitors for the treatment of cancer.

A. Armirotti, N. Brindani, M. De Vivo, 2023, European journal of medicinal chemistry.

Design, Synthesis, Dynamic Docking, Biochemical Characterization, and in Vivo Pharmacokinetics Studies of Novel Topoisomerase II Poisons with Promising Antiproliferative Activity

Jissy A. Kuriappan, R. Bertorelli, A. Armirotti, 2020, Journal of medicinal chemistry.

Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer

A. Ganesan, R. Bertorelli, A. Armirotti, 2023, Journal of medicinal chemistry.

Synthetic and analytical strategies for the quantification of phenyl-γ-valerolactone conjugated metabolites in human urine.

L. Calani, F. Brighenti, D. Del Rio, 2017, Molecular nutrition & food research.

Targeting the conserved active site of splicing machines with specific and selective small molecule modulators

M. Marcia, M. Vivo, Jacopo Manigrasso, 2023, bioRxiv.

Design, synthesis, docking, and biochemical characterization of non-nucleoside SARS-CoV-2 RdRp inhibitors

A. Armirotti, M. De Vivo, Andrea Menichetti, 2023, Bioorganic & Medicinal Chemistry.

Bioavailability of Black Tea Theaflavins: Absorption, Metabolism, and Colonic Catabolism.

M. Lean, A. Crozier, D. Del Rio, 2017, Journal of agricultural and food chemistry.

Phenyl-γ-valerolactones, flavan-3-ol colonic metabolites, protect brown adipocytes from oxidative stress without affecting their differentiation or function.

M. Vacca, A. Vidal-Puig, S. Rodriguez-Cuenca, 2017, Molecular nutrition & food research.

CDC42 Inhibitors Alter Patterns of Vessel Arborization in Skin and Tumors in vivo

M. De Vivo, S. M. Bertozzi, M. Summa, 2024, bioRxiv.