J. Elsner

发表

Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy.

G. Fenalti, L. LeBrun, Dan Zhu, 2019, Journal of medicinal chemistry.

Bicyclic melatonin receptor agonists containing a ring-junction nitrogen: Synthesis, biological evaluation, and molecular modeling of the putative bioactive conformation.

F. Boeckler, K. Davidson, D. Sugden, 2006, Bioorganic & medicinal chemistry.

Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines. Implications for the binding mode of heterocyclic dopamine D3 receptor agonists.

F. Boeckler, P. Gmeiner, H. Hübner, 2005, Journal of medicinal chemistry.

Highly potent 5-aminotetrahydropyrazolopyridines: enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions.

P. Gmeiner, J. Whistler, Nuska Tschammer, 2011, Journal of medicinal chemistry.

Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115.

P. Worland, D. Mortensen, B. Cathers, 2015, Journal of medicinal chemistry.

Discovery of the c-Jun N-Terminal Kinase Inhibitor CC-90001.

Y. Satoh, B. Bennett, D. Mortensen, 2021, Journal of medicinal chemistry.

Discovery of mammalian target of rapamycin (mTOR) kinase inhibitor CC-223.

P. Worland, D. Mortensen, B. Cathers, 2015, Journal of medicinal chemistry.

The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen.

L. LeBrun, Dan Zhu, B. Pagarigan, 2017, Journal of medicinal chemistry.

Structure-Guided Optimization Provides a Series of TTK Protein Inhibitors with Potent Antitumor Activity.

L. LeBrun, T. Tran, K. Leftheris, 2021, Journal of medicinal chemistry.

Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115.

P. Worland, D. Mortensen, B. Cathers, 2015, Journal of medicinal chemistry.