Ayumu Okuda

Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor alpha agonists.

B. Staels, J. Fruchart, Takaaki Araki, 2007, Bioorganic & Medicinal Chemistry Letters.

Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor alpha agonists.

B. Staels, J. Fruchart, Keisuke Inoue, 2007, Bioorganic & medicinal chemistry letters.

Discovery of a 2-hydroxyacetophenone derivative as an outstanding linker to enhance potency and β-selectivity of liver X receptor agonist.

Yuichiro Watanabe, Y. Matsumoto, Tomoaki Koshizawa, 2016, Bioorganic & medicinal chemistry.

Optimization of a novel series of potent and orally bioavailable GPR119 agonists.

Tomoaki Koshizawa, Tomoaki Fukuda, T. Morimoto, 2017, Bioorganic & medicinal chemistry letters.

Design, synthesis and pharmacology of 1,1-bistrifluoromethylcarbinol derivatives as liver X receptor β-selective agonists.

Yuichiro Watanabe, Y. Yamaguchi, K. Shibuya, 2015, Bioorganic & medicinal chemistry letters.

Design and discovery of 2-oxochromene derivatives as liver X receptor β-selective agonists.

Yuichiro Watanabe, Y. Yamaguchi, K. Shibuya, 2015, Bioorganic & medicinal chemistry letters.

Discovery of novel spiro[chromane-2,4'-piperidine] derivatives as potent and orally bioavailable G-protein-coupled receptor 119 agonists.

Tomoaki Koshizawa, Tomoaki Fukuda, T. Morimoto, 2018, Bioorganic & medicinal chemistry letters.