P. Gasdaska

发表

Over-expression of DT-diaphorase in transfected NIH 3T3 cells does not lead to increased anticancer quinone drug sensitivity: a questionable role for the enzyme as a target for bioreductively activated anticancer drugs.

G. Powis, A. Gallegos, K. Sherrill, 1995, Anticancer research.

Site-directed mutagenesis of active site cysteines in human thioredoxin produces competitive inhibitors of human thioredoxin reductase and elimination of mitogenic properties of thioredoxin.

G. Powis, M. Berggren, J. Oblong, 1994, The Journal of biological chemistry.

Selenium and the thioredoxin redox system: effects on cell growth and death.

D. Kirkpatrick, G. Powis, J. Gasdaska, 1997, Oncology research.

The predicted amino acid sequence of human thioredoxin is identical to that of the autocrine growth factor human adult T-cell derived factor (ADF): thioredoxin mRNA is elevated in some human tumors.

G. Powis, I. Cotgreave, J. Oblong, 1994, Biochimica et biophysica acta.

Increased NAD(P)H:(quinone-acceptor)oxidoreductase activity is associated with density-dependent growth inhibition of normal but not transformed cells.

G. Powis, J. Schlager, R. Scott, 1993, Cancer research.

Dominant Effects ofTubulin Overexpression inSaccharomyces cerevisiae

D. Burke, P. Gasdaska, 1989 .

Human thioredoxin reductase gene localization to chromosomal position 12q23-q24.1 and mRNA distribution in human tissue.

G. Powis, J. Gasdaska, A. Gallegos, 1996, Genomics.

Interaction between FLASH and Lsm11 is essential for histone pre-mRNA processing in vivo in Drosophila.

Z. Dominski, R. Duronio, W. Marzluff, 2011, RNA.

Expression in Human Non-Small Cell Lung Carcinoma Cigarette Smoking Is a Determinant of DT-Diaphorase Gene Updated

G. Powis, P. Hyman, P. Gasdaska, 2006 .

Cigarette smoking is a determinant of DT-diaphorase gene expression in human non-small cell lung carcinoma.

G. Powis, P. Hyman, P. Gasdaska, 1993, Cancer research.

The thioredoxin/thioredoxin reductase redox system and control of cell growth.

D. Kirkpatrick, G. Powis, M. Berggren, 1994, Oncology research.

Cloning, sequencing and functional expression of a novel human thioredoxin reductase

G. Powis, M. Berggren, P. Gasdaska, 1999, FEBS letters.

Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells.

G. Paine-Murrieta, C. Taylor, G. Powis, 1996, Cancer research.

Site-directed mutagenesis of Lys36 in human thioredoxin: the highly conserved residue affects reduction rates and growth stimulation but is not essential for the redox protein's biochemical or biological properties.

G. Powis, M. Berggren, J. Oblong, 1995, Biochemistry.

Dominant effects of tubulin overexpression in Saccharomyces cerevisiae

L. Hartwell, D. Burke, P. Gasdaska, 1989, Molecular and cellular biology.

Drosophila histone locus bodies form by hierarchical recruitment of components

Z. Dominski, R. Duronio, W. Marzluff, 2011, The Journal of cell biology.

Purification of human thioredoxin reductase: properties and characterization by absorption and circular dichroism spectroscopy.

G. Powis, K. Sherrill, J. Oblong, 1993, Biochemistry.

Cloning and sequencing of a human thioredoxin reductase

G. Powis, J. Gasdaska, P. Gasdaska, 1995, FEBS letters.

Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia.

G. Powis, J. Gasdaska, M. Berggren, 1996, Anticancer research.

Regulation of Human Thioredoxin Reductase Expression and Activity by 3′-Untranslated Region Selenocysteine Insertion Sequence and mRNA Instability Elements*

J. Harney, G. Powis, J. Gasdaska, 1999, The Journal of Biological Chemistry.

An alternatively spliced form of NQO1 (DT-diaphorase) messenger RNA lacking the putative quinone substrate binding site is present in human normal and tumor tissues.

G. Powis, P. Gasdaska, H. Fisher, 1995, Cancer research.

Drosophila histone locus bodies form by hierarchical recruitment of components

Z. Dominski, R. Duronio, W. Marzluff, 2011, The Journal of cell biology.