Hiroyuki Kawai

发表

Ionic liquids as media for nucleophilic ring opening fluorination of aziridines

N. Shibata, Shuichi Nakamura, T. Toru, 2009 .

Solkane® 365mfc is an environmentally benign alternative solvent for trifluoromethylation reactions

N. Shibata, Shuichi Nakamura, Hiroyuki Kawai, 2009 .

Asymmetric synthesis of agrochemically attractive trifluoromethylated dihydroazoles and related compounds under organocatalysis.

N. Shibata, Hiroyuki Kawai, 2014, Chemical record.

Enantioselective synthesis of epoxides having a tetrasubstituted trifluoromethylated carbon center: methylhydrazine-induced aerobic epoxidation of β,β-disubstituted enones.

A. Yamano, Etsuko Tokunaga, N. Shibata, 2013, Angewandte Chemie.

Diastereoselective Additive Trifluoromethylation/Halogenation of Isoxazole Triflones: Synthesis of All-Carbon-Functionalized Trifluoromethyl Isoxazoline Triflones

Hiroyasu Sato, Etsuko Tokunaga, N. Shibata, 2014, ChemistryOpen.

Enantioselective synthesis of trifluoromethyl-substituted 2-isoxazolines: asymmetric hydroxylamine/enone cascade reaction.

Etsuko Tokunaga, N. Shibata, M. Shiro, 2010, Angewandte Chemie.

Organocatalytic asymmetric synthesis of trifluoromethyl-substituted diarylpyrrolines: enantioselective conjugate cyanation of β-aryl-β-trifluoromethyl-disubstituted enones.

Hiroyasu Sato, Etsuko Tokunaga, N. Shibata, 2012, Angewandte Chemie.

Catalytic enantioselective synthesis of β-trifluoromethyl pyrrolines.

Takashi Matsumoto, Hiroyasu Sato, Etsuko Tokunaga, 2012, Chemical communications.

Partially saturated fluorinated heterocycles: diastereo- and enantioselective synthesis of β-trifluoromethyl-pyrroline carboxylates.

Hiroyasu Sato, Etsuko Tokunaga, N. Shibata, 2012, Chemical communications.

Cu-mediated chemoselective trifluoromethylation of benzyl bromides using shelf-stable electrophilic trifluoromethylating reagents.

Etsuko Tokunaga, N. Shibata, T. Furukawa, 2011, Organic letters.

A sterically demanding organo-superbase avoids decomposition of a naked trifluoromethyl carbanion directly generated from fluoroform.

Etsuko Tokunaga, N. Shibata, Hiroyuki Kawai, 2013, Organic & biomolecular chemistry.

Trifluoromethylation of aromatic isoxazoles: regio- and diastereoselective route to 5-trifluoromethyl-2-isoxazolines.

Etsuko Tokunaga, N. Shibata, M. Shiro, 2011, Angewandte Chemie.

Recent advances in enantioselective trifluoromethylation reactions

N. Shibata, S. Mizuta, Hiroyuki Kawai, 2008 .

Efficient access to trifluoromethyl diarylpyrrolines and their N-oxides through enantioselective conjugate addition of nitromethane to β,β-disubstituted enones.

Etsuko Tokunaga, N. Shibata, T. Kitayama, 2013, Angewandte Chemie.

Regioselective synthesis of pyrazole triflones based on triflyl alkyne cycloadditions.

Etsuko Tokunaga, N. Shibata, Hiroyuki Kawai, 2012, Organic letters.

Enantioselective Synthesis of Trifluoromethyl‐Substituted 2‐Isoxazolines: Asymmetric Hydroxylamine/Enone Cascade Reaction.

Etsuko Tokunaga, N. Shibata, M. Shiro, 2010 .

Catalytic enantioselective trifluoromethylation of azomethine imines with trimethyl(trifluoromethyl)silane.

N. Shibata, M. Shiro, Shuichi Nakamura, 2009, Angewandte Chemie.

Synthesis of Isoxazole Triflones

Etsuko Tokunaga, N. Shibata, Yutaka Sugita, 2012 .

Diastereoselective Additive Trifluoromethylation/Halogenation of Isoxazole Triflones: Synthesis of All‐Carbon‐Functionalized Trifluoromethyl Isoxazoline Triflones.

Hiroyasu Sato, Etsuko Tokunaga, N. Shibata, 2014 .

Enantioselective Synthesis of 5-Trifluoromethyl-2-isoxazolines and Their N-Oxides by [Hydroxy(tosyloxy)iodo]benzene-Mediated Oxidative N–O Coupling

Etsuko Tokunaga, N. Shibata, Hiroyuki Kawai, 2013 .

Cinchona alkaloid/TMAF combination: Enantioselective trifluoromethylation of aryl aldehydes

Etsuko Tokunaga, N. Shibata, S. Mizuta, 2013 .

Construction of Trifluoromethyl‐Bearing Quaternary Carbon Centers by Intramolecular Decarboxylative Allylation of α‐Trifluoromethyl β‐Keto Esters

Etsuko Tokunaga, N. Shibata, D. Cahard, 2011 .

Asymmetric Synthesis of Efavirenz via Organocatalyzed Enantioselective Trifluoromethylation

Etsuko Tokunaga, N. Shibata, T. Kitayama, 2014 .

A New Synthetic Approach to Efavirenz through Enantioselective Trifluoromethylation by Using the Ruppert–Prakash Reagent

Etsuko Tokunaga, N. Shibata, T. Kitayama, 2011 .

Cinchona alkaloid-catalyzed asymmetric trifluoromethylation of alkynyl ketones with trimethylsilyl trifluoromethane.

Etsuko Tokunaga, N. Shibata, M. Shiro, 2010, Organic letters.

Phosphonium Formation by Facile Carbon-Phosphorus Reductive Elimination from Gold(III).

W. J. Wolf, Matthew S. Winston, F. Toste, 2016, Journal of the American Chemical Society.

Synthesis of novel C2-symmetric chiral crown ethers and their application to enantioselective trifluoromethylation of aldehydes and ketones

H. Masuda, Y. Funahashi, N. Shibata, 2009 .

Synthesis of 4'-O-acylanthracyclines

H. Umezawa, N. Ōtake, K. Tatsuta, 1988 .

N-2-Iodobenzylcinchoninium bromide is effective for catalytic enantioselective trifluoromethylation of azomethine imines in Solkane® 365mfc

Etsuko Tokunaga, N. Shibata, Hiroyuki Kawai, 2012 .