N. Sirisoma

发表

Metabolism and mode of action of cis- and trans-3-pinanones (the active ingredients of hyssop oil)

J. Casida, S. Sparks, K. M. Höld, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps.

S. Skvortsov, S. Kasibhatla, V. Baichwal, 2007, Cancer research.

Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positions.

William E. Kemnitzer, S. Kasibhatla, Candace Crogan-Grundy, 2008, Bioorganic & medicinal chemistry letters.

Discovery of substituted N′-(2-oxoindolin-3-ylidene)benzohydrazides as new apoptosis inducers using a cell- and caspase-based HTS assay

S. Cai, J. Drewe, B. Tseng, 2009, Bioorganic & Medicinal Chemistry Letters.

1-(N-alkylamino)-11-(N-ethylamino)-4,8-diazaundecanes: simple synthetic polyamine analogues that differentially alter tubulin polymerization.

P. Woster, R. Casero, Z. Wu, 1999, Journal of medicinal chemistry.

Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: structure-activity relationships of the 4-anilino group.

S. Kasibhatla, Yang Wang, S. Cai, 2006, Bioorganic & medicinal chemistry.

Synthesis of protected allylic amines via palladium(0)-catalyzed amination of allylic acetates

P. Woster, N. Sirisoma, 1998 .

Discovery of N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a potent apoptosis inducer and efficacious anticancer agent with high blood brain barrier penetration.

Mark B. Anderson, S. Kasibhatla, S. Cai, 2009, Journal of medicinal chemistry.

Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure-activity relationships of the 4-, 5-, 6-, 7- and 8-positions.

William E. Kemnitzer, S. Kasibhatla, Candace Crogan-Grundy, 2009, Bioorganic & medicinal chemistry letters.

Discovery of 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a potent inducer of apoptosis with high in vivo activity.

Mark B. Anderson, S. Kasibhatla, V. Baichwal, 2008, Journal of medicinal chemistry.

Discovery of 4-anilino-N-methylthieno[3,2-d]pyrimidines and 4-anilino-N-methylthieno[2,3-d]pyrimidines as potent apoptosis inducers.

William E. Kemnitzer, C. May, S. Cai, 2009, Bioorganic & medicinal chemistry letters.

Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 9-oxo-9H-fluorene ring.

William E. Kemnitzer, S. Kasibhatla, Candace Crogan-Grundy, 2009, Bioorganic & medicinal chemistry letters.

α-Iodocycloalkenones: Synthesis of (±)-epibatidine

Carl R. Johnson, N. Sirisoma, 1998 .

The natural polyamine spermine functions directly as a free radical scavenger.

J. Zweier, P. Woster, P. Kuppusamy, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the carboxamide group.

William E. Kemnitzer, S. Kasibhatla, Candace Crogan-Grundy, 2009, Bioorganic & medicinal chemistry letters.

Detoxification of α- and β-Thujones (the Active Ingredients of Absinthe): Site Specificity and Species Differences in Cytochrome P450 Oxidation in Vitro and in Vivo

J. Casida, K. M. Höld, N. Sirisoma, 2001 .

Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo.

J. Casida, K. M. Höld, N. Sirisoma, 2001, Chemical research in toxicology.

Novel alkylpolyamine analogues that possess both antitrypanosomal and antimicrosporidial activity.

P. Woster, L. Weiss, R. Casero, 2001, Bioorganic & medicinal chemistry letters.

A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid.

D. Green, L. Qiu, S. Kasibhatla, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Fipronil-based photoaffinity probe for Drosophila and human β3 GABA receptors

J. Casida, M. Tomizawa, G. S. Ratra, 2001 .

Preparation of α-Halo-α,β-Unsaturated Bicyclic Lactams and Their Use in Palladium-Catalyzed Cross Coupling Reactions

Carl R. Johnson, M. Braun, B. Newhouse, 1993 .

Discovery of N-methyl-4-(4-methoxyanilino)quinazolines as potent apoptosis inducers. Structure-activity relationship of the quinazoline ring.

Mark B. Anderson, S. Kasibhatla, S. Cai, 2010, Bioorganic & medicinal chemistry letters.

α- and β-Thujones (Herbal Medicines and Food Additives): Synthesis and Analysis of Hydroxy and Dehydro Metabolites

J. Casida, K. M. Höld, N. Sirisoma, 2001 .

Alpha-thujone (the active component of absinthe): gamma-aminobutyric acid type A receptor modulation and metabolic detoxification.

J. Casida, T. Narahashi, T. Ikeda, 2000, Proceedings of the National Academy of Sciences of the United States of America.