Peter McDonald

发表

Small-Molecule Disruptors of Mutant Huntingtin-Calmodulin Protein-Protein Interaction Attenuate Deleterious Effects of Mutant Huntingtin.

J. Aubé, N. Muma, Anuradha Roy, 2022, ACS chemical neuroscience.

Identification of Vaccinia Virus Inhibitors and Cellular Functions Necessary for Efficient Viral Replication by Screening Bioactives and FDA-Approved Drugs

Shuai Cao, Zhilong Yang, Anuradha Roy, 2020, Vaccines.

YM155 Inhibits NleB and SseK Arginine Glycosyltransferase Activity

P. Hardwidge, Anuradha Roy, Congrui Zhu, 2021, Pathogens.

High-Throughput Screening for Bacterial Glycosyltransferase Inhibitors

P. Hardwidge, Pradip Maity, Digamber Rane, 2018, Front. Cell. Infect. Microbiol..

Identification of Survival Genes in Human Glioblastoma Cells by Small Interfering RNA Screening

Fang Zhang, Nikhil G Thaker, Peter R McDonald, 2009, Molecular Pharmacology.

Identification of Survival Genes in Human Glioblastoma Cells Using siRNA Screening

Peter R. McDonald, I. Pollack, J. Lazo, 2009 .

Fluorescence High-Throughput Screening for Inhibitors of TonB Action

P. Klebba, S. Newton, Anuradha Roy, 2017, Journal of bacteriology.

Cooperative p16 and p21 action protects female astrocytes from transformation

N. Warrington, Kelsey L. Tinkum, Najla Kfoury, 2018, Acta Neuropathologica Communications.

Designing, optimizing, and implementing high-throughput siRNA genomic screening with glioma cells for the discovery of survival genes and novel drug targets

Peter R. McDonald, I. Pollack, J. Lazo, 2010, Journal of Neuroscience Methods.

Comparative oncology approach to drug repurposing in osteosarcoma

K. Neville, T. Iwakuma, A. Parrales, 2018, PloS one.

Alkylation Sensitivity Screens Reveal a Conserved Cross-species Functionome

I. Pollack, T. Begley, J. Lazo, 2012, Molecular Cancer Research.

Cross-species Functionome Alkylation Sensitivity Screens Reveal a Conserved

I. Pollack, T. Begley, J. Lazo, 2012 .

Functionome Alkylation Sensitivity Screens Reveal a Conserved Cross-species

I. Pollack, T. Begley, J. Lazo, 2012 .

Identification of Chemosensitivity Nodes for Vinblastine through Small Interfering RNA High-Throughput Screens

I. Pollack, J. Lazo, T. Shun, 2011, Journal of Pharmacology and Experimental Therapeutics.

Functional genomic analysis of glioblastoma multiforme through short interfering RNA screening: a paradigm for therapeutic development.

Peter R. McDonald, I. Pollack, J. Lazo, 2010, Neurosurgical focus.

Identification of novel potential cancer therapies by synthetic lethal screening

Peter McDonald, 2008 .

Targeting Epithelial-Mesenchymal Transition for Identification of Inhibitors for Pancreatic Cancer Cell Invasion and Tumor Spheres Formation

Ping Chen, Melinda A. Broward, Anuradha Roy, 2016, PloS one.

The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase

Anthony R. Fehr, J. Gagné, G. Poirier, 2020, bioRxiv.

Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening

Peter R. McDonald, Anthony R. Fehr, A. Leung, 2022, Antiviral Research.

Results from phase 2 registration trial of SL-401 in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN): Lead-in completed, expansion stage ongoing.

Peter R. McDonald, M. Konopleva, H. Kantarjian, 2016 .

Screening of Natural Compounds as Activators of the Keap1-Nrf2 Pathway

Peter R. McDonald, Jie Liu, C. Klaassen, 2013, Planta Medica.

Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase

R. Honzatko, S. Nelson, Anuradha Roy, 2022, bioRxiv.

Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

D. Dixon, Lan Lan, Liang Xu, 2015, ACS chemical biology.

Synthetic Protection Short Interfering RNA Screen Reveals Glyburide as a Novel Radioprotector

J. Lazo, J. Greenberger, V. Kagan, 2009, Radiation research.

Simple and Rapid High-Throughput Assay to Identify HSV-1 ICP0 Transactivation Inhibitors

David K. Johnson, Anuradha Roy, D. Davido, 2021, bioRxiv.

Results of Pivotal Phase 2 Clinical Trial of Tagraxofusp (SL-401) in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

M. Konopleva, H. Kantarjian, A. Lane, 2018, Blood.

Implementation of a High-Throughput Screen for Identifying Small Molecules to Activate the Keap1-Nrf2-ARE Pathway

R. Chaguturu, Jie Liu, C. Klaassen, 2012, PloS one.

Open access high throughput drug discovery in the public domain: a Mount Everest in the making.

Sitta Sittampalam, Anuradha Roy, Rathnam Chaguturu, 2010, Current pharmaceutical biotechnology.

Results from Phase 2 Trial Ongoing Expansion Stage of SL-401 in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

M. Konopleva, H. Kantarjian, A. Lane, 2016 .

Drug screening to target nuclear orphan receptor NR4A2 for cancer therapeutics.

R. Perez, Anuradha Roy, T. Komiya, 2017, Translational lung cancer research.

A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells

Peter R. McDonald, P. Wipf, J. Lazo, 2008, Molecular Cancer Therapeutics.

The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase

Anthony R. Fehr, J. Gagné, G. Poirier, 2020, Journal of Virology.

Recent Trends in Collaborative, Open Source Drug Discovery

Anuradha Roy, Peter R. McDonald, Rathnam Chaguturu, 2011 .

Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening

Anthony R. Fehr, A. Leung, D. Ferraris, 2022, bioRxiv.

Identification of Chemosensitivity Nodes for Vinblastine through Small Interfering RNA High-Throughput Screens

I. Pollack, J. Lazo, T. Shun, 2011, Journal of Pharmacology and Experimental Therapeutics.

Screening of Natural Compounds as Activators of the Keap1-Nrf2 Pathway

Jie Liu, C. Klaassen, K. Wu, 2013, Planta Medica.