J. Gupton

发表

Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison.

M. Cabot, I. Newsham, G. Kellogg, 2007, Biochemical pharmacology.

Chemistry of fluorinated vinamidinium salts: novel reactions of β-trifluoromethyl vinamidinium salt with Grignard reagents

T. Kubota, T. Ishihara, H. Yamanaka, 1999 .

Effects of a novel microtubule-depolymerizer on pro-inflammatory signaling in RAW264.7 macrophages.

A. Gonye, S. Espinosa de los Reyes, O. Quintero, 2018, Chemico-biological interactions.

Effects of a pyrrole-based, microtubule-depolymerizing compound on RAW 264.7 macrophages.

K. Fischer‐Stenger, J. Gupton, John A. Ciemniecki, 2016, Chemico-biological interactions.

Autophagy, cell death and sustained senescence arrest in B16/F10 melanoma cells and HCT-116 colon carcinoma cells in response to the novel microtubule poison, JG-03-14

Jorge A. Almenara, D. Gewirtz, Xu Di, 2013, Cancer Chemotherapy and Pharmacology.

Synthetic application of fluorinated vinamidinium salts: Synthesis of fluorinated 1,3-butadienylphosphonates by the reaction with Horner–Wadsworth–Emmons reagents

T. Ishihara, S. Arimitsu, T. Konno, 2006 .

Photochemical rearrangements of cross-conjugated cyclohexadienones related to epimaalienone

H. Deutsch, D. Caine, J. Gupton, 1978 .

Identification and Characterization of a New Tubulin-Binding Tetrasubstituted Brominated Pyrrole

Jonathan E. Hempel, S. Dakshanamurthy, E. Hamel, 2007, Molecular Pharmacology.

Developing novel C-4 analogues of pyrrole-based antitubulin agents: weak but critical hydrogen bonding in the colchicine site.

G. Kellogg, S. Mooberry, Chenxiao Da, 2013, MedChemComm.

A CONVENIENT STEREOSPECIFIC SYNTHESIS OF (+)-ALPHA-CYPERONE

D. Caine, J. Gupton, 1974 .

Docking and hydropathic scoring of polysubstituted pyrrole compounds with antitubulin activity.

M. Fornabaio, G. Kellogg, D. Gewirtz, 2008, Bioorganic & medicinal chemistry.

Reactions of β-fluorovinamidinium salt with activated methylene compounds

K. Kase, T. Ishihara, H. Yamanaka, 1998 .

Pyrrole-Based Antitubulin Agents: Two Distinct Binding Modalities are Predicted for C-2 Analogs in the Colchicine Site.

G. Kellogg, S. Mooberry, Chenxiao Da, 2012, ACS medicinal chemistry letters.

Interference with endothelial cell function by JG-03-14, an agent that binds to the colchicine site on microtubules.

D. Gewirtz, E. Schwartz, N. Dalyot-Herman, 2009, Biochemical pharmacology.

Reaction of β-fluorinated vinamidinium salts with Grignard reagents and reducing agents

T. Ishihara, T. Konno, H. Yamanaka, 2001 .

Reaction of β-fluorovinamidinium salt with Grignard reagents. Facile and efficient route to (Z)-α-fluoro-α,β-unsaturated aldehydes

T. Ishihara, H. Yamanaka, J. Gupton, 1998 .

Synthesis of polyfluoroalkoxylated pyrimidines and pyrazoles by using novel β-polyfluoroalkoxy vinamidinium salts

Mitsuyoshi Katayama, K. Kase, T. Ishihara, 1998 .

Efficient and General Synthesis of Novelβ-Polyfluoroalkoxy Vinamidinium Salts

Mitsuyoshi Katayama, K. Kase, T. Ishihara, 1997 .

Insecticides Based on Differences in Metabolic Pathways

G. Cunningham, J. Gupton, R. T. Mayer, 1990 .

How to deal with low-resolution target structures: using SAR, ensemble docking, hydropathic analysis, and 3D-QSAR to definitively map the αβ-tubulin colchicine site.

Glen E Kellogg, Chenxiao Da, G. Kellogg, 2013, Journal of medicinal chemistry.

Biological Characterization of an Improved Pyrrole-Based Colchicine Site Agent Identified through Structure-Based Design

G. Kellogg, S. Mooberry, Chenxiao Da, 2016, Molecular Pharmacology.

Photochemical rearrangements of cross-conjugated cyclohexadienones. Application to the synthesis of (-)-4-epiglobulol and (+)-4-epiaromadendrene

D. Caine, J. Gupton, 1975 .