Guanglin Chen

发表

Nitrogen-containing derivatives of O-tetramethylquercetin: Synthesis and biological profiles in prostate cancer cell models.

Shilong Zheng, Guangdi Wang, Qiao-Hong Chen, 2019, Bioorganic chemistry.

Aerobic Decomposition of Trialkylquercetins: Structure Characterization and Antiproliferative Effect

L. Rakotondraibe, Qiao-Hong Chen, Xiaojie Zhang, 2016, Natural product communications.

Synthesis and Anti-Proliferative Effects of Quercetin Derivatives

L. Rakotondraibe, Qiao-Hong Chen, Xiaojie Zhang, 2015, Natural product communications.

An amide mimic of desTHPdactylolide: Total synthesis and antiproliferative evaluation.

Guangdi Wang, Qiao-Hong Chen, Qiang Zhang, 2021, Bioorganic & medicinal chemistry letters.

5-Substituted 3, 3', 4', 7-tetramethoxyflavonoids - a novel class of potent DNA triplex specific binding ligands.

Qiao-Hong Chen, L. Xue, Guanglin Chen, 2022, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of niclosamide PROTACs

Guangdi Wang, Qiao-Hong Chen, Qiang Zhang, 2022, Bioorganic & medicinal chemistry letters.

3-O-Carbamoyl-5,7,20-O-trimethylsilybins: Synthesis and Preliminary Antiproliferative Evaluation

Guangdi Wang, Qiao-Hong Chen, Qiang Zhang, 2021, Molecules.

Design, synthesis, and evaluation of novel heteroaromatic analogs of curcumin as anti-cancer agents.

Shilong Zheng, Guangdi Wang, Amjad Hussain, 2014, European journal of medicinal chemistry.

Structure-Activity Relationship and Pharmacokinetic Studies of 1,5-Diheteroarylpenta-1,4-dien-3-ones: A Class of Promising Curcumin-Based Anticancer Agents.

Shilong Zheng, Guangdi Wang, Changde Zhang, 2015, Journal of medicinal chemistry.

The Effects of Curcumin-based Compounds on Proliferation and Cell Death in Cervical Cancer Cells.

Qiao-Hong Chen, L. Dejean, Xiaojie Zhang, 2015, Anticancer Research.

1-Chromonyl-5-Imidazolylpentadienone Demonstrates Anti-Cancer Action against TNBC and Exhibits Synergism with Paclitaxel

G. Brailoiu, A. Lakshmikuttyamma, Qiao-Hong Chen, 2020, International journal of molecular sciences.

Generation and characterization of an estrogen receptor alpha‐iCre knock‐in mouse

C. Ko, Chan Jin Park, P. Lin, 2017, Genesis.

Optimized synthesis and antiproliferative activity of desTHPdactylolides.

James D White, Shilong Zheng, Guangdi Wang, 2018, Bioorganic & medicinal chemistry.

New Zampanolide Mimics: Design, Synthesis, and Antiproliferative Evaluation

Guangdi Wang, Qiao-Hong Chen, Qiang Zhang, 2020, Molecules.

Synthesis and antiproliferative evaluation of new zampanolide mimics.

James D White, Shilong Zheng, Guangdi Wang, 2019, Organic & biomolecular chemistry.

PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer

J. Pollack, Jieqing Li, Q. Hao, 2019, Science Advances.

O-Aminoalkyl-O-Trimethyl-2,3-Dehydrosilybins: Synthesis and In Vitro Effects Towards Prostate Cancer Cells

Shenmin Zhang, Shilong Zheng, Guangdi Wang, 2018, Molecules.

A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-κB inactivation in colorectal cancer cells

J. Vadgama, Yong Wu, P. Dutta, 2019, Oncotarget.

Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: Antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies.

Shanchun Guo, Shilong Zheng, Guangdi Wang, 2017, European journal of medicinal chemistry.

Structure-activity relationship studies of 1,7-diheteroarylhepta-1,4,6-trien-3-ones with two different terminal rings in prostate epithelial cell models.

Shilong Zheng, Guangdi Wang, Qiao-Hong Chen, 2017, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of 1,9-diheteroarylnona-1,3,6,8-tetraen-5-ones as a new class of anti-prostate cancer agents.

Shilong Zheng, Guangdi Wang, Qiao-Hong Chen, 2016, Bioorganic & medicinal chemistry.

Synthesis and evaluation of 1,7-diheteroarylhepta-1,4,6-trien-3-ones as curcumin-based anticancer agents.

Shilong Zheng, Guangdi Wang, Qiao-Hong Chen, 2016, European journal of medicinal chemistry.

A new class of hybrid anticancer agents inspired by the synergistic effects of curcumin and genistein: Design, synthesis, and anti-proliferative evaluation.

Nithya Subrahmanyam, F. León, Qiao-Hong Chen, 2015, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro activities on anti-platelet aggregation of 4-methoxy-1,3-phthalamidesamides and benzenedisulfonamides

Guanglin Chen, Zhihao Zhang, Xiujie Liu, 2019, Medicinal Chemistry Research.

Synthesis and in vitro activities on anti-platelet aggregation of 4-methoxyisophthalamides

Yan Wang, Lili Liu, Xiujie Liu, 2018, Medicinal Chemistry Research.

A new class of flavonol-based anti-prostate cancer agents: Design, synthesis, and evaluation in cell models.

Shilong Zheng, Guangdi Wang, Qiao-Hong Chen, 2016, Bioorganic & medicinal chemistry letters.

Structure-activity relationship and pharmacokinetic studies of 3-O-substitutedflavonols as anti-prostate cancer agents.

Shanchun Guo, Shilong Zheng, Guangdi Wang, 2018, European journal of medicinal chemistry.

3-O-Substituted-3',4',5'-trimethoxyflavonols: Synthesis and cell-based evaluation as anti-prostate cancer agents.

Shilong Zheng, Guangdi Wang, Qiao-Hong Chen, 2017, Bioorganic & medicinal chemistry.

Optimization of diarylpentadienones as chemotherapeutics for prostate cancer.

Shanchun Guo, Shilong Zheng, Guangdi Wang, 2018, Bioorganic & Medicinal Chemistry.

Targeting of PP2Cδ By a Small Molecule C23 Inhibits High Glucose-Induced Breast Cancer Progression In Vivo.

K. Nguyen, Q. Hao, J. Vadgama, 2019, Antioxidants & redox signaling.

Comp34 displays potent preclinical antitumor efficacy in triple-negative breast cancer via inhibition of NUDT3-AS4, a novel oncogenic long noncoding RNA

Jieqing Li, Q. Hao, W. Cao, 2020, Cell Death & Disease.

5- or/and 20-O-alkyl-2,3-dehydrosilybins: Synthesis and biological profiles on prostate cancer cell models.

Shenmin Zhang, Shilong Zheng, Guangdi Wang, 2017, Bioorganic & medicinal chemistry.

3-O-Alkyl-2,3-dehydrosilibinins: Two synthetic approaches and in vitro effects toward prostate cancer cells.

Shilong Zheng, Guangdi Wang, Qiao-Hong Chen, 2016, Bioorganic & medicinal chemistry letters.

Targeted 19F-tags to detect amino acids in complex mixtures using NMR spectroscopy.

Qiao-Hong Chen, Guanglin Chen, Keeton H. Montgomery, 2022, Journal of Fluorine Chemistry.

Tricyclic Diterpenoids Selectively Suppress Androgen Receptor-Positive Prostate Cancer Cells

Guangdi Wang, Qiao-Hong Chen, Qiang Zhang, 2023, Molecules.