J. Uchic

发表

Implication of P450-metabolite complex formation in the nonlinear pharmacokinetics and metabolic fate of (+/-)-(1'R*,3R*)-3-phenyl-1-[(1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200) in dogs.

A. D. Rodrigues, K. Marsh, A. Buko, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: design, synthesis, and optimization of pharmacokinetics and biological activities.

S. Badylak, F. Haviv, J. Henkin, 2005, Journal of medicinal chemistry.

Combined enzymatic and chemical approaches to the synthesis of unique polyribonucleotides.

M. Uchic, A. D. Broom, J. Uchic, 1976, Biochimica et biophysica acta.

Studies on polyribonucleotides. Synthesis of a polyinosinic: 6-thioinosinic acid copolymer.

M. Uchic, A. D. Broom, J. Uchic, 1973, Biochemical and biophysical research communications.

The use of s-2-cyanoethyl phosphorothioate in the preparation of oligo 5'-deoxy-5'-thiothymidylates

J. Kresse, K. L. Nagpal, J. Nagyvary, 1975, Nucleic Acids Res..

Reaction of 3-(β-D-Ribofuranosyl)adenine with phosphorus oxychloride. Isolation and characterization of 3(β-D-ribofuranosyl)adenine 9,5′(P)-cyclic phosphonate.

J. Uchic, 1977 .

Potent inhibition of the cytochrome P-450 3A-mediated human liver microsomal metabolism of a novel HIV protease inhibitor by ritonavir: A positive drug-drug interaction.

G. Granneman, Y. Yao, D. Hickman, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Measurement of liver microsomal cytochrome p450 (CYP2D6) activity using [O-methyl-14C]dextromethorphan.

A. D. Rodrigues, M. Kukulka, J. Machinist, 1994, Analytical biochemistry.

Metabolism and Disposition of the HIV-1 Protease Inhibitor Lopinavir (ABT-378) Given in Combination with Ritonavir in Rats, Dogs, and Humans

D. Kempf, H. Sham, K. Marsh, 2004, Pharmaceutical Research.

[3H]A-317491, a Novel High-Affinity Non-Nucleotide Antagonist That Specifically Labels Human P2X2/3 and P2X3 Receptors

M. Williams, Chih-Hung Lee, M. Jarvis, 2004, Journal of Pharmacology and Experimental Therapeutics.

Polymerization of aromatic nuclei. XII. Oligomerization of halobenzenes by aluminum chloride‐cupric chloride

P. Kovacic, L. Hsu, J. Uchic, 1967 .

In vitro metabolism of the HIV-1 protease inhibitor ABT-378: species comparison and metabolite identification.

D. Kempf, H. Sham, D. Betebenner, 1999, Drug metabolism and disposition: the biological fate of chemicals.