Takeo Umemura

Inhibition of catechol-O-methyltransferase in the cynomolgus monkey by opicapone after acute and repeated administration

Makoto Tanaka, T. Kitajima, P. Soares-da-Silva, 2018, Neuropharmacology.

Modeling and simulation of bone mineral density response from a phase 2 study of ONO‐5334, a new cathepsin K inhibitor, to support dose selection in osteoporosis

I. Ieiri, H. Kastrissios, J. Monteleone, 2014, Journal of clinical pharmacology.

Population pharmacokinetic and pharmacodynamic modeling of different formulations of ONO‐5334, cathepsin K inhibitor, in Caucasian and Japanese postmenopausal females

I. Ieiri, Chihiro Hasegawa, T. Ohno, 2014, Journal of clinical pharmacology.