Denise Hermes

Selective Transgenic Expression of Mutant Ubiquitin in Purkinje Cell Stripes in the Cerebellum

D. Hopkins, B. M. Verheijen, F. V. van Leeuwen, 2016, The Cerebellum.

Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C‐terminal hydrolase L3 (UCH‐L3)

H. Steinbusch, N. Dantuma, F. V. van Leeuwen, 2011, FEBS letters.

Localization of mutant ubiquitin in the brain of a transgenic mouse line with proteasomal inhibition and its validation at specific sites in Alzheimer's disease

H. Steinbusch, D. Hopkins, B. Küsters, 2015, Front. Neuroanat..

Mutant ubiquitin decreases amyloid β plaque formation in a transgenic mouse model of Alzheimer’s disease

H. Steinbusch, D. Fischer, B. Hobo, 2012, Neurochemistry International.

Paradoxical effects of mutant ubiquitin on Aβ plaque formation in an Alzheimer mouse model

H. Steinbusch, J. Ruijter, W. Annaert, 2018, Neurobiology of Aging.

Long-term proteasomal inhibition in transgenic mice by UBB+1 expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients

H. Fuchs, D. Hopkins, H. Schulz, 2012, Acta Neuropathologica.