I. Canals

发表

Transcription factor-based direct conversion of human fibroblasts to functional astrocytes

Henrik Ahlenius, A. Gonzalez-Ramos, M. Kokaia, 2022, Stem cell reports.

Rapid and efficient induction of functional astrocytes from human pluripotent stem cells

Henrik Ahlenius, D. Bryder, J. Bengzon, 2018, Nature Methods.

FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis

Leal Oburoglu, I. Canals, Anuntxi Monsalve, 2022, Frontiers in Cell and Developmental Biology.

NGN2 mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities

N. Elvassore, F. Michielin, M. Muraca, 2021, Frontiers in Cellular Neuroscience.

Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome.

L. Gort, D. Grinberg, L. Vilageliu, 2019, Stem cell research.

Generation of two compound heterozygous HGSNAT-mutated lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo C syndrome.

D. Grinberg, L. Vilageliu, M. Cozar, 2019, Stem cell research.

Neuronal and Astrocytic Differentiation from Sanfilippo C Syndrome iPSCs for Disease Modeling and Drug Development

A. Ribes, D. Grinberg, L. Vilageliu, 2020, Journal of clinical medicine.

Activity and High-Order Effective Connectivity Alterations in Sanfilippo C Patient-Specific Neuronal Networks

Jordi Soriano, Isaac Canals, Simone Merlin, 2015, Stem cell reports.

Genome Editing Using Cas9-gRNA Ribonucleoprotein in Human Pluripotent Stem Cells for Disease Modeling.

D. Grinberg, L. Vilageliu, Noelia Benetó, 2021, Methods in molecular biology.

CRISPR/Cas9 Genome Engineering in Human Pluripotent Stem Cells for Modeling of Neurological Disorders.

I. Canals, H. Ahlenius, 2021, Methods in molecular biology.

Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence

S. Soneji, C. Guibentif, N. Woods, 2021, EMBO reports.

Therapeutic strategies based on modified U1 snRNAs and chaperones for Sanfilippo C splicing mutations

A. Pshezhetsky, M. Prata, P. Jordan, 2014, Orphanet Journal of Rare Diseases.

Transcription Factor-Based Strategies to Generate Neural Cell Types from Human Pluripotent Stem Cells.

Ella Quist, I. Canals, H. Ahlenius, 2021, Cellular reprogramming.

Rapid and efficient induction of functional astrocytes from human pluripotent stem cells

D. Bryder, J. Bengzon, E. Monni, 2018, Nature Methods.

Sanfilippo Syndrome: Molecular Basis, Disease Models and Therapeutic Approaches

D. Grinberg, L. Vilageliu, Noelia Benetó, 2020, International journal of molecular sciences.

Molecular analysis of Sanfilippo syndrome type C in Spain: seven novel HGSNAT mutations and characterization of the mutant alleles

M. Pineda, D. Grinberg, A. Chabás, 2011, Clinical genetics.

Mitochondrial Dysfunction and Calcium Dysregulation in Leigh Syndrome Induced Pluripotent Stem Cell Derived Neurons

Miguel Ángel Martín, J. Ehinger, E. Elmér, 2020, International journal of molecular sciences.

EXTL2 and EXTL3 inhibition with siRNAs as a promising substrate reduction therapy for Sanfilippo C syndrome

D. Grinberg, L. Vilageliu, M. Cozar, 2015, Scientific Reports.

In Vitro Functional Characterization of Human Neurons and Astrocytes Using Calcium Imaging and Electrophysiology.

Z. Kokaia, D. Tornero, M. G. Hansen, 2019, Methods in molecular biology.

Transcription Factor–Forced Astrocytic Differentiation Impairs Human Glioblastoma Growth In Vitro and In Vivo

J. Bengzon, F. Stefani, Oskar G. Zetterdahl, 2022, Molecular cancer therapeutics.

Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia

J. Soriano, M. Pajares, A. Heuer, 2023, Brain communications.