Nick Mullen

SIRT1–NOX4 signaling axis regulates cancer cachexia

D. Tuveson, P. Singh, M. Hollingsworth, 2020, The Journal of experimental medicine.

Metabolic Rewiring by Loss of Sirt5 Promotes Kras-induced Pancreatic Cancer Progression.

J. Auwerx, D. Tuveson, A. Mai, 2021, Gastroenterology.

ENT1 blockade by CNX-774 overcomes resistance to DHODH inhibition in pancreatic cancer.

Shikhar Sharma, Pankaj Singh, D. Sykes, 2022, Cancer letters.

Nucleotide metabolism: a pan-cancer metabolic dependency

Pankaj Singh, Nick Mullen, Nicholas J Mullen, 2023, Nature reviews. Cancer.

Nucleotide metabolism: a pan-cancer metabolic dependency

Pankaj Singh, Nick Mullen, 2023, Nature Reviews Cancer.

DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

M. Hollingsworth, D. Price, Pankaj Singh, 2023, bioRxiv.

DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

A. Natarajan, Nina V. Chaika, Kamiya Mehla, 2024, eLife.