Timothy R. Newhouse

发表

Masha Elkin, Anthony C Scruse, Suzanne M. Szewczyk, 2017, Journal of the American Chemical Society.

Total synthesis guided structure elucidation of (+)-psychotetramine.

P. Baran, H. Takayama, Timothy R. Newhouse, 2011, Angewandte Chemie.

A tetradentate ligand for the enantioselective Ti(IV)-promoted oxidation of sulfides to sulfoxides: origin of enantioselectivity.

E. Corey, Xin Li, M. Blewett, 2012, Journal of the American Chemical Society.

Scalable total syntheses of N-linked tryptamine dimers by direct indole-aniline coupling: psychotrimine and kapakahines B and F.

P. Baran, K. Eastman, C. Lewis, 2010, Journal of the American Chemical Society.

Palladium-Catalyzed α,β-Dehydrogenation of Esters and Nitriles.

Yifeng Chen, Timothy R. Newhouse, Justin P Romaire, 2015, Journal of the American Chemical Society.

Isomer-Specific Hydrogen Bonding as a Design Principle for Bidirectionally Quantitative and Redshifted Hemithioindigo Photoswitches.

J. Zweig, Timothy R. Newhouse, 2017, Journal of the American Chemical Society.

Assembly of the Limonoid Architecture by a Divergent Approach: Total Synthesis of (±)-Andirolide N via (±)-8α-Hydroxycarapin.

Timothy R. Newhouse, Alexander W. Schuppe, 2017, Journal of the American Chemical Society.

Effects of π-extension on pyrrole hemithioindigo photoswitches

J. Zweig, Junrou Huang, Timothy R. Newhouse, 2019, Tetrahedron.

Enantiospecific total syntheses of kapakahines B and F.

P. Baran, C. Lewis, Timothy R. Newhouse, 2009, Journal of the American Chemical Society.

Unified Total Synthesis of the Limonoid Alkaloids: Strategies for the De Novo Synthesis of Highly Substituted Pyridine Scaffolds.

Xin Eric Wang, J. P. Loria, V. Dixit, 2022, Chem.

The psychotrimine natural products have antibacterial activity against Gram-positive bacteria and act via membrane disruption

F. Romesberg, P. Baran, Mark A. Schallenberger, 2010, The Journal of Antibiotics.

Analysis of chain length, substitution patterns, and unsaturation of AM-404 derivatives as 20S proteasome stimulators.

A. Bhardwaj, Yizhou Zhao, Christine S. Muli, 2019, Bioorganic & medicinal chemistry letters.

Pentosinane, a Post-Translational Modification of Human Proteins with Underappreciated Stability.

D. Spiegel, Matthew D. Streeter, Yannan Liu, 2022, Journal of the American Chemical Society.

Computationally Augmented Retrosynthesis: Total Synthesis of Paspaline A and Emindole PB

Daria E. Kim, J. Zweig, Timothy R. Newhouse, 2018 .

α,β-Dehydrogenation of esters with free O H and N H functionalities via allyl-palladium catalysis

Yizhou Zhao, P. Dubé, Suzanne M. Szewczyk, 2018, Tetrahedron.

Methods Utilizing First-Row Transition Metals in Natural Product Total Synthesis.

Daria E. Kim, J. Zweig, Timothy R. Newhouse, 2017, Chemical reviews.

If C-H bonds could talk: selective C-H bond oxidation.

P. Baran, Timothy R. Newhouse, 2011, Angewandte Chemie.

The economies of synthesis.

Phil S. Baran, R. W. Hoffmann, Reinhard W. Hoffmann, 2009, Chemical Society reviews.

Copper-Catalyzed Vinylogous Aerobic Oxidation of Unsaturated Compounds with Air.

Hai‐Jun Zhang, S. Pan, L. Yin, 2018, Journal of the American Chemical Society.

Allyl-Nickel Catalysis Enables Carbonyl Dehydrogenation and Oxidative Cycloalkenylation of Ketones.

Suzanne M. Szewczyk, Timothy R. Newhouse, David Huang, 2019, Journal of the American Chemical Society.

Total Synthesis of Paspaline A and Emindole PB Enabled by Computational Augmentation of a Transform-Guided Retrosynthetic Strategy.

T. Newhouse, Daria E. Kim, J. Zweig, 2019, Journal of the American Chemical Society.

An invocation for computational evaluation of isomerization transforms: cationic skeletal reorganizations as a case study.

Timothy R Newhouse, Alexander W Schuppe, Yannan Liu, 2020, Natural product reports.

Enhanced reactivity in dioxirane C-H oxidations via strain release: a computational and experimental study.

Timothy R Newhouse, Robert S Paton, Phil S Baran, 2013, The Journal of organic chemistry.

Total Synthesis of (+)-Granatumine A and Related Bislactone Limonoid Alkaloids via a Pyran to Pyridine Interconversion.

Yannan Liu, Yizhou Zhao, Timothy R. Newhouse, 2019, Journal of the American Chemical Society.

Total synthesis of (+/-)-psychotrimine.

P. Baran, Timothy R. Newhouse, 2008, Journal of the American Chemical Society.

Scalable synthesis of enaminones utilizing Gold's reagents.

James M. Cabrera, Timothy R. Newhouse, Alexander W. Schuppe, 2017, Tetrahedron, asymmetry.

Total Synthesis of (-)-Xylogranatopyridine B via a Palladium-Catalyzed Oxidative Stannylation of Enones.

Yifeng Chen, Timothy R. Newhouse, Alexander W. Schuppe, 2018, Journal of the American Chemical Society.

Nickel-Catalyzed Difunctionalization of Unactivated Alkenes Initiated by Unstabilized Enolates.

Diego Olivieri, Yang Sun, Timothy R. Newhouse, 2019, Journal of the American Chemical Society.

The Economies of Synthesis

R. W. Hoffmann, P. Baran, Timothy R. Newhouse, 2010 .

Dehydrogenative Pd and Ni Catalysis for Total Synthesis.

Timothy R. Newhouse, David Huang, 2021, Accounts of chemical research.

Allyl-Palladium-Catalyzed Ketone Dehydrogenation Enables Telescoping with Enone α,β-Vicinal Difunctionalization.

Yizhou Zhao, Yifeng Chen, Timothy R. Newhouse, 2017, Angewandte Chemie.

Aryl-Nickel-Catalyzed Benzylic Dehydrogenation of Electron-Deficient Heteroarenes.

Timothy R. Newhouse, David Huang, Pengpeng Zhang, 2019, Journal of the American Chemical Society.

Synthesis of Cyclic Enones by Allyl-Palladium-Catalyzed α,β-Dehydrogenation.

Yizhou Zhao, Timothy R. Newhouse, David Huang, 2018, Organic letters.

Allyl-Palladium Catalyzed Alpha,Beta-Dehydrogenation of Carboxylic Acids via Enediolates

Yizhou Zhao, Yifeng Chen, Timothy R. Newhouse, 2017 .

Amide α,β-Dehydrogenation Using Allyl-Palladium Catalysis and a Hindered Monodentate Anilide.

Aneta Turlik, Yifeng Chen, Timothy R. Newhouse, 2016, Journal of the American Chemical Society.

Amide α,β‐Dehydrogenation Using Allyl‐Palladium Catalysis and a Hindered Monodentate Anilide.

Aneta Turlik, Yifeng Chen, Timothy R. Newhouse, 2016 .

Dehydrogenation Adjacent to Carbonyls Using Palladium–Allyl Intermediates

Aneta Turlik, Yifeng Chen, Timothy R. Newhouse, 2015, Synlett.

Versatile approaches for the synthesis of fused-ring γ-lactones utilizing cyclopropane intermediates.

E. Corey, Philip S. J. Kaib, Timothy R. Newhouse, 2013, Organic letters.

Vinylogous acyl triflates as an entry point to α,β-disubstituted cyclic enones via Suzuki-Miyaura cross-coupling.

Daria E. Kim, Timothy R. Newhouse, Yingchuan Zhu, 2019, Organic & biomolecular chemistry.

Zinc-mediated anionic cyclization of unstabilized ketone enolates with unactivated alkenes

Diego Olivieri, Timothy R. Newhouse, David Huang, 2020 .

Scalable procedure for the fragmentation of hydroperoxides mediated by copper and iron tetrafluoroborate salts.

Timothy R. Newhouse, Alexander W. Schuppe, David Huang, 2016, Organic & biomolecular chemistry.

Computational chemistry strategies in natural product synthesis.

Masha Elkin, Timothy R Newhouse, Masha Elkin, 2018, Chemical Society reviews.

Allyl-Palladium-Catalyzed α,β-Dehydrogenation of Carboxylic Acids via Enediolates.

Yizhou Zhao, Yifeng Chen, Timothy R. Newhouse, 2017, Angewandte Chemie.

If C—H Bonds Could Talk: Selective C—H Bond Oxidation.

P. Baran, Timothy R. Newhouse, 2011 .

Total Synthesis of (+)-Shearilicine.

Daria E. Kim, Abbigayle Cuomo, Isaiah Aguilar, 2023, Journal of the American Chemical Society.

Traversing Biosynthetic Carbocation Landscapes in the Total Synthesis of Andrastin and Terretonin Meroterpenes.

D. Tantillo, Gong Xu, T. Maimone, 2017, Angewandte Chemie.

Computational and Synthetic Investigation of Cationic Rearrangement in the Putative Biosynthesis of Justicane Triterpenoids.

Masha Elkin, Anthony C Scruse, Aneta Turlik, 2018, Angewandte Chemie.

Convergent Total Synthesis of Principinol D, a Rearranged Kaurane Diterpenoid.

T. Newhouse, Anthony C Scruse, Aneta Turlik, 2019, Journal of the American Chemical Society.

A neural network model informs the total synthesis of clovane sesquiterpenoids

Yizhou Zhao, Masha Elkin, Timothy Newhouse, 2021, Nature Synthesis.

Coordination-Controlled Nickel-Catalyzed Benzylic Allylation of Unactivated Electron-Deficient Heterocycles.

J. Wang, Timothy R. Newhouse, Pengpeng Zhang, 2022, Angewandte Chemie.

Feed-Forward Neural Network for Predicting Enantioselectivity of the Asymmetric Negishi Reaction

Jinhua J. Song, V. Batista, R. Crabtree, 2023, ACS central science.

Concomitant conformational dimorphism in 1,2-bis(9-anthryl)acetylene

S. Price, R. Goldstein, Thomas J Sisto, 2015 .

Isomer-Specific Hydrogen Bonding as a Design Principle for Bidirectionally Quantitative and Redshifted Hemithioindigo Photoswitches.

J. Zweig, Timothy R. Newhouse, 2017, Journal of the American Chemical Society.

Role of Benzylic Deprotonation in Nickel-Catalyzed Benzylic Dehydrogenation

Timothy R. Newhouse, Pengpeng Zhang, Rachel Cantrell, 2021, Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry.

Dehydrogenation Adjacent to Carbonyls Using Palladium–Allyl Intermediates

Aneta Turlik, Yifeng Chen, Timothy R. Newhouse, 2015, Synlett.

Methods Utilizing First-Row Transition Metals in Natural Product Total Synthesis.

Daria E. Kim, J. Zweig, Timothy R. Newhouse, 2017, Chemical reviews.

Convergent Total Synthesis of Principinol D, a Rearranged Kaurane Diterpenoid.

Anthony C Scruse, Aneta Turlik, Yifeng Chen, 2019, Journal of the American Chemical Society.

A tetradentate ligand for the enantioselective Ti(IV)-promoted oxidation of sulfides to sulfoxides: origin of enantioselectivity.

E. Corey, Xin Li, Timothy R. Newhouse, 2012, Journal of the American Chemical Society.

Ligand-Based Principal Component Analysis Followed by Ridge Regression: Application to an Asymmetric Negishi Reaction

H. R. Kelly, Timothy R. Newhouse, Sanil Sreekumar, 2024, ACS Catalysis.

S ITE -S PECIFIC T EMPLATE G ENERATIVE A PPROACH FOR R ETROSYNTHETIC P LANNING

Timothy R. Newhouse, Sanil Sreekumar, Frederic G. Buono, 2022 .

Enhanced Ligand Discovery through Generative AI and Latent-Space Exploration: Application to the Mizoroki-Heck Reaction

Timothy R. Newhouse, Sanil Sreekumar, Victor S. Batista, 2022 .

Scalable procedure for the fragmentation of hydroperoxides mediated by copper and iron tetrafluoroborate salts.

Timothy R. Newhouse, Alexander W. Schuppe, David Huang, 2016, Organic & biomolecular chemistry.

Comprehensive Mechanistic Analysis of Palladium- and Nickel-Catalyzed α,β-Dehydrogenation of Carbonyls via Organozinc Intermediates.

Timothy R. Newhouse, Suzanne M Szewczyk, Alexandra K Bodnar, 2024, The Journal of organic chemistry.