Huayun Feng

发表

Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies.

Meng Lei, Yongqiang Zhu, Jing Shi, 2018, Bioorganic & medicinal chemistry.

In vitro and in vivo efficacy of the novel oral proteasome inhibitor NNU546 in multiple myeloma

E. Izumchenko, Meng Lei, Yongqiang Zhu, 2020, Aging.

Preparation and biological evaluation of soluble tetrapeptide epoxyketone proteasome inhibitors.

Jian Shen, Meng Lei, Xiaoqing Du, 2019, Bioorganic & medicinal chemistry.

Discovery of a novel dipeptidyl boronic acid proteasome inhibitor for the treatment of multiple myeloma and triple-negative breast cancer.

Meng Lei, Yongqiang Zhu, Jia Liu, 2019, Organic & biomolecular chemistry.

Design, synthesis, SAR discussion, in vitro and in vivo evaluation of novel selective EGFR modulator to inhibit L858R/T790M double mutants.

Meng Lei, Yongqiang Zhu, Hao Cheng, 2017, European journal of medicinal chemistry.

3D-QSAR-aided design, synthesis, in vitro and in vivo evaluation of dipeptidyl boronic acid proteasome inhibitors and mechanism studies.

Hailing Li, Meng Lei, Yongqiang Zhu, 2016, Bioorganic & medicinal chemistry.

Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed from αα- and αβ-amino acids.

Cheng Jiang, Meng Lei, Yongqiang Zhu, 2016, Bioorganic & medicinal chemistry letters.

Double-layer hypernetwork model with bimodal peak characteristics

Zhao Hai-xing, Huayun Feng, Lu Wen, 2021 .

Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies.

Meng Lei, Yongqiang Zhu, Jing Shi, 2018, Bioorganic & medicinal chemistry.