Genki Minegishi

CYP3A4 Induction in the Liver and Intestine of Pregnane X Receptor/CYP3A-Humanized Mice: Approaches by Mass Spectrometry Imaging and Portal Blood Analysis

M. Oshimura, K. Igarashi, J. Kanno, 2019, Molecular Pharmacology.

Comparison of the hepatic metabolism of triazolam in wild-type andCyp3a-knockout mice for understanding CYP3A-mediated metabolism inCYP3A-humanised mice in vivo

M. Oshimura, Y. Kazuki, H. Akita, 2019, Xenobiotica; the fate of foreign compounds in biological systems.

Influence of MDR1 gene polymorphism (2677G>T) on expression and function of P-glycoprotein at the blood-brain barrier: utilizing novel P-glycoprotein humanized mice with mutation.

Y. Kazuki, S. Abe, K. Kazuki, 2022, Pharmacogenetics and genomics.

Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure.

J. Cheah, T. Huang, M. Shirouzu, 2022, Cell metabolism.

Characterization of P-Glycoprotein Humanized Mice Generated by Chromosome Engineering Technology: Its Utility for Prediction of Drug Distribution to the Brain in Humans

M. Oshimura, Y. Kazuki, S. Abe, 2018, Drug Metabolism and Disposition.

Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse Cyp2c and Cyp3a Genes

Y. Kazuki, S. Abe, K. Kazuki, 2022, Drug Metabolism and Disposition.

In vivo evaluation of intestinal human CYP3A inhibition by macrolide antibiotics in CYP3A-humanised mice

Y. Kazuki, H. Akita, Kaoru Kobayashi, 2021, Xenobiotica; the fate of foreign compounds in biological systems.