Yufang Cheng

发表

Inhibition of PDE4 by FCPR16 induces AMPK‐dependent autophagy and confers neuroprotection in SH‐SY5Y cells and neurons exposed to MPP+‐induced oxidative insult

Haitao Wang, Jiang-Ping Xu, Dan Li, 2019, Free radical biology & medicine.

Involvement of PI3K/Akt/FoxO3a and PKA/CREB Signaling Pathways in the Protective Effect of Fluoxetine Against Corticosterone-Induced Cytotoxicity in PC12 Cells

Haitao Wang, B. Niu, Yiwen Li, 2016, Journal of Molecular Neuroscience.

Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition

Wenhua Zheng, Zhong-Zhen Zhou, Hai-Tao Wang, 2017, The Journal of Pharmacology and Experimental Therapeutics.

The phosphodiesterase-4 inhibitor, FCPR16, attenuates ischemia-reperfusion injury in rats subjected to middle cerebral artery occlusion and reperfusion

Wenhua Zheng, Haitao Wang, Chang Huang, 2018, Brain Research Bulletin.

Inhibition of phosphodiesterase-4 suppresses HMGB1/RAGE signaling pathway and NLRP3 inflammasome activation in mice exposed to chronic unpredictable mild stress

Haitao Wang, Yunyun Qin, Jinfeng Xie, 2020, Brain, Behavior, and Immunity.

Neuroprotection, learning and memory improvement of a standardized extract from Renshen Shouwu against neuronal injury and vascular dementia in rats with brain ischemia.

Jiao Guo, Weijian Bei, Quanlin Gu, 2015, Journal of ethnopharmacology.

Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia–reperfusion injury

Han-Ting Zhang, Shenglan Guo, S. Ouyang, 2006, Brain Research.

Inhibition of phosphodiesterase-4 reverses the cognitive dysfunction and oxidative stress induced by Aβ25–35 in rats

Yiwen Li, Chuang Wang, Danna Gan, 2016, Metabolic Brain Disease.

Design, synthesis and biological evaluation of substituted aminopyridazin-3(2H)-ones as G0/G1-phase arresting agents with apoptosis-inducing activities.

Zhong-Zhen Zhou, Jiang-Ping Xu, Hai-Tao Wang, 2017, European journal of medicinal chemistry.

Promotion of β-amyloid production by C-reactive protein and its implications in the early pathogenesis of Alzheimer’s disease

Heng Zhou, Tie-jun Li, Jiang-Ping Xu, 2012, Neurochemistry International.

Roflupram, a Phosphodiesterase 4 Inhibitior, Suppresses Inflammasome Activation through Autophagy in Microglial Cells.

Wenhua Zheng, Haitao Wang, Jiahong Zhong, 2017, ACS chemical neuroscience.

Forkhead box O transcription factors as possible mediators in the development of major depression

Haitao Wang, Jiangping Xu, Zhong-Ping Feng, 2015, Neuropharmacology.

Systematic correlation between spine plasticity and the anxiety/depression-like phenotype induced by corticosterone in mice

Yufang Cheng, Yupin Chen, Ming-zi Zhang, 2013, Neuroreport.

FCPR16, a novel phosphodiesterase 4 inhibitor, produces an antidepressant-like effect in mice exposed to chronic unpredictable mild stress

Haitao Wang, Chang Huang, Hui Yu, 2019, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats.

Heng Zhou, Han-Ting Zhang, Chuang Wang, 2012, The international journal of neuropsychopharmacology.

FFPM, a PDE4 inhibitor, reverses learning and memory deficits in APP/PS1 transgenic mice via cAMP/PKA/CREB signaling and anti-inflammatory effects

Haitao Wang, B. Niu, Hui Yu, 2017, Neuropharmacology.

C-Reactive Protein Induces Tau Hyperphosphorylation via GSK3β Signaling Pathway in SH-SY5Y Cells

Haitao Wang, Yiwen Li, Haibiao Guo, 2015, Journal of Molecular Neuroscience.

Memory deficits and neurochemical changes induced by C-reactive protein in rats: implication in Alzheimer’s disease

Han-Ting Zhang, Tie-jun Li, Jiang-Ping Xu, 2009, Psychopharmacology.

Discovery of N-Alkyl Catecholamides as Selective Phosphodiesterase-4 Inhibitors with Anti-neuroinflammation Potential Exhibiting Antidepressant-like Effects at Non-emetic Doses.

Hui Yu, Zhong-Zhen Zhou, Hai-Tao Wang, 2017, ACS chemical neuroscience.

Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25–35 or Aβ1–40 peptide in rats

Han-Ting Zhang, Ying Huang, Chuang Wang, 2010, Psychopharmacology.

Involvement of norepinephrine and serotonin system in antidepressant-like effects of hederagenin in the rat model of unpredictable chronic mild stress-induced depression

Jiang-Ping Xu, Hai-Tao Wang, Haibiao Guo, 2015, Pharmaceutical biology.

Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice.

Haitao Wang, Qiuping Zhong, Yufang Cheng, 2017, Laboratory investigation; a journal of technical methods and pathology.

Prevention of cerebral ischemia-induced memory deficits by inhibition of phosphodiesterase-4 in rats

Han-Ting Zhang, Ling-Xia Li, Chuang Wang, 2011, Metabolic Brain Disease.

Antidepressant effect of the extracts from Fructus Akebiae

Dan Zhou, Jiang-Ping Xu, Huan-bing Lin, 2010, Pharmacology Biochemistry and Behavior.

Development of highly potent phosphodiesterase 4 inhibitors with anti-neuroinflammation potential: Design, synthesis, and structure-activity relationship study of catecholamides bearing aromatic rings.

Chang Huang, Zhong-Zhen Zhou, Hai-Tao Wang, 2016, European journal of medicinal chemistry.

Involvement of PI3K/Akt/FoxO3a and PKA/CREB Signaling Pathways in the Protective Effect of Fluoxetine Against Corticosterone-Induced Cytotoxicity in PC12 Cells

Haitao Wang, B. Niu, Yiwen Li, 2016, Journal of Molecular Neuroscience.

Phosphodiesterase-4D Knock-Out and RNA Interference-Mediated Knock-Down Enhance Memory and Increase Hippocampal Neurogenesis via Increased cAMP Signaling

J. O'Donnell, M. Conti, Han-Ting Zhang, 2011, The Journal of Neuroscience.

Chlorbipram: a novel PDE4 inhibitor with improved safety as a potential antidepressant and cognitive enhancer.

Zhong-Zhen Zhou, Jiang-Ping Xu, Yufang Cheng, 2013, European journal of pharmacology.

RNA interference-mediated knockdown of long-form phosphodiesterase-4D (PDE4D) enzyme reverses amyloid-β42-induced memory deficits in mice.

Haitao Wang, Han-Ting Zhang, Chuang Wang, 2013, Journal of Alzheimer's disease : JAD.

Discovery of 9H-purins as potential tubulin polymerization inhibitors: Synthesis, biological evaluation and structure-activity relationships.

Zhong-Zhen Zhou, Jiang-Ping Xu, Hai-Tao Wang, 2017, European journal of medicinal chemistry.

Donepezil improves learning and memory deficits in APP/PS1 mice by inhibition of microglial activation

Haitao Wang, C. Zhang, Y. Cheng, 2015, Neuroscience.

C-Reactive Protein Induces Tau Hyperphosphorylation via GSK3β Signaling Pathway in SH-SY5Y Cells

Haitao Wang, Yiwen Li, Haibiao Guo, 2015, Journal of Molecular Neuroscience.

Inhibition of phosphodiesterase-4 reverses the cognitive dysfunction and oxidative stress induced by Aβ25–35 in rats

Yiwen Li, Chuang Wang, Danna Gan, 2016, Metabolic Brain Disease.

Roflupram, a novel phosphodiesterase 4 inhibitor, inhibits lipopolysaccharide-induced neuroinflammatory responses through activation of the AMPK/Sirt1 pathway.

Haitao Wang, Dan Li, Yunyun Qin, 2020, International immunopharmacology.