M. Cohen

发表

Acetylcholine-induced production of reactive oxygen species in adult rabbit ventricular myocytes is dependent on phosphatidylinositol 3- and Src-kinase activation and mitochondrial K(ATP) channel opening.

J. Downey, S. Critz, O. Oldenburg, 2003, Journal of molecular and cellular cardiology.

576 a 1-Adrenergic Agonists Precondition Rabbit Ischemic Myocardium Independent of Adenosine by Direct Activation of Protein Kinase C

J. Downey, Yongge Liu, A. Tsuchida, 2005 .

a1-Adrenergic Agonists Precondition Rabbit Ischemic Myocardium Independent of Adenosine by Direct Activation of Protein Kinase C

J. Downey, Yongge Liu, A. Tsuchida, 2005 .

Opening of ATP-sensitive potassium channels causes generation of free radicals in vascular smooth muscle cells

J. Downey, S. Critz, O. Oldenburg, 2002, Basic Research in Cardiology.

Thaffium-201 ScintigraphicQuantitation of Regional Flow Disparity and Subsequent Redistributionin Dogs

R. Steingart, M. Cohen, 2006 .

Mapping Preconditioning's Signaling Pathways

J. Downey, T. Krieg, M. Cohen, 2008, Annals of the New York Academy of Sciences.

What Are Optimal P2Y12 Inhibitor and Schedule of Administration in Patients With Acute Coronary Syndrome?

J. Downey, M. Cohen, 2020, Journal of cardiovascular pharmacology and therapeutics.

The Highly Selective Caspase-1 Inhibitor VX-765 Provides Additive Protection Against Myocardial Infarction in Rat Hearts When Combined With a Platelet Inhibitor

J. Downey, D. Alvarez, J. Audia, 2017, Journal of cardiovascular pharmacology and therapeutics.

Biventricular diastolic dysfunction, thrombocytopenia, and red blood cell macrocytosis in experimental pulmonary arterial hypertension

J. Y. Lee, K. Fagan, T. Stevens, 2020, Pulmonary circulation.

Myocardial Stunning After Electrocution With Complete Reversibility Within 24 Hours: Role of Repeat Transthoracic Echocardiograms in Potential Cardiac Transplant Donors

Sarina Sachdev, Nikky Bardia, L. Nguyen, 2018, Cardiology research.

AMISTAD trials: possible reasons for lack of success.

J. Downey, M. Cohen, 2006, Journal of the American College of Cardiology.

Protection from postconditioning depends on the number of short ischemic insults in anesthetized pigs

J. Downey, E. Iliodromitis, D. Kremastinos, 2006, Basic Research in Cardiology.

Loss of myocardial protection from ischemic preconditioning following chronic exposure to R(-)-N6-(2-phenylisopropyl)adenosine is related to defect at the adenosine A1 receptor

J. Downey, M. Hashimi, J. Thornton, 1998, Molecular and Cellular Biochemistry.

Rapid cooling preserves the ischaemic myocardium against mitochondrial damage and left ventricular dysfunction.

Michael V. Cohen, J. Downey, J. Dubois-Randé, 2009, Cardiovascular research.

Smaller infarct after preconditioning does not predict extent of early functional improvement of reperfused heart.

J. Downey, Xi-ming Yang, M. Cohen, 1999, American journal of physiology. Heart and circulatory physiology.

Society for Cardiovascular Magnetic Resonance 2019 Case of the Week series

Bryant M. Baldwin, A. Hamdy, C. Hamilton-Craig, 2021, Journal of Cardiovascular Magnetic Resonance.

Preconditioning During Ischemia: Basic Mechanisms and Potential Clinical Applications

M. Cohen, L. M. Downey, 1995 .

Cangrelor-Mediated Cardioprotection Requires Platelets and Sphingosine Phosphorylation

J. Downey, D. Yellon, R. Bell, 2016, Cardiovascular Drugs and Therapy.

Preconditioning : what it is and how it works

J. Downey, M. Cohen, 2004 .

A2B adenosine receptors inhibit superoxide production from mitochondrial complex I in rabbit cardiomyocytes via a mechanism sensitive to Pertussis toxin

J. Downey, T. Rich, Xiulan Yang, 2011, British journal of pharmacology.

Thaffium-201ScintigraphicQuantitation of RegionalFlow Disparity and SubsequentRedistribution in Dogs

R. Steingart, M. Cohen, 1986 .

Both A2a and A2b adenosine receptors at reperfusion are necessary to reduce infarct size in mouse hearts.

J. Downey, T. Krieg, C. Methner, 2010, American journal of physiology. Heart and circulatory physiology.

Cytoprotective Effect of Vitamin D on Doxorubicin-Induced Cardiac Toxicity in Triple Negative Breast Cancer

Natalie R. Gassman, H. Bryant, Michele A. Schuler, 2021, International journal of molecular sciences.

CVR-2018-935R1 Title: Circulating blood cells and extracellular vesicles in acute cardioprotection Short title: Circulating cells and vesicles in cardioprotection

J. Downey, K. Preissner, P. Ferdinandy, 2019 .

M itochondrial K channels: role in cardioprotection

J. Downey, D. Yellon, O. Oldenburg, 2002 .

MISTAD Trials : Possible easons for Lack of Success

M. Cohen, M. Downey, 2016 .

Mitochondrial K(ATP) channels in preconditioning.

J. Downey, O. Oldenburg, M. Cohen, 2003, Journal of molecular and cellular cardiology.

Ischemic preconditioning depends on interaction between mitochondrial KATP channels and actin cytoskeleton.

J. Downey, C. Baines, S. Critz, 1999, American journal of physiology. Heart and circulatory physiology.

Attenuation of infarction in cynomolgus monkeys: preconditioning and postconditioning

J. Downey, Yongge Liu, N. Tandon, 2009, Basic Research in Cardiology.

A cetylcholine leads to free radical production dependent on KATP channels , G proteins , phosphatidylinositol 3-kinase and tyrosinei kinase

J. Downey, O. Oldenburg, J. Benoit, 2001 .

Status of P2Y12 treatment must be considered in evaluation of myocardial ischaemia/reperfusion injury.

J. Downey, M. Cohen, 2015, Cardiovascular research.

Coronary collaterals : clinical & experimental observations

M. Cohen, 1985 .

Remote Ischemic Conditioning: more explanations and more expectations

J. Downey, E. Iliodromitis, M. Cohen, 2022, Basic Research in Cardiology.

Volatile Anesthetics Protect the Ischemic Rabbit Myocardium from Infarction

Michael V. Cohen, J. Downey, D. Cope, 1997, Anesthesiology.

Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion.

J. Downey, S. Critz, T. Krahn, 2007, Journal of molecular and cellular cardiology.

Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade.

J. Downey, S. Philipp, Xi-ming Yang, 2006, Cardiovascular research.

NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO.

J. Downey, T. Krieg, Xi-ming Yang, 2004, Journal of molecular and cellular cardiology.

Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection.

J. Downey, S. Critz, T. Krieg, 2004, American journal of physiology. Heart and circulatory physiology.

Acetylcholine but not adenosine triggers preconditioning through PI3-kinase and a tyrosine kinase.

Michael V. Cohen, J. Downey, Q. Qin, 2003, American journal of physiology. Heart and circulatory physiology.

The Role of Protein Kinase C in Ischemic Preconditioning

J. Downey, M. Goto, M. Cohen, 1996, Annals of the New York Academy of Sciences.

Atrial natriuretic peptide administered just prior to reperfusion limits infarction in rabbit hearts

J. Downey, S. Philipp, Xi-ming Yang, 2006, Basic Research in Cardiology.

Protein Kinase G Transmits the Cardioprotective Signal From Cytosol to Mitochondria

J. Downey, T. Lincoln, I. West, 2005, Circulation research.

Mechanism of Cardioprotection by Early Ischemic Preconditioning

Michael V. Cohen, J. Downey, Xiulan Yang, 2010, Cardiovascular Drugs and Therapy.

Signaling pathways in ischemic preconditioning

Michael V. Cohen, J. Downey, Amanda M. Davis, 2007, Heart Failure Reviews.

The small chill: mild hypothermia for cardioprotection?

Renaud Tissier, J. Downey, B. Ghaleh, 2010, Cardiovascular research.

Mitochondria and Their Role in Ischemia/Reperfusion Injury

J. Downey, M. Cohen, S. Phillip, 2007 .

Cardioprotective PKG-independent NO signaling at reperfusion.

J. Downey, Yanping Liu, Xi-ming Yang, 2010, American journal of physiology. Heart and circulatory physiology.

Opening of Mitochondrial KATP Channels Triggers the Preconditioned State by Generating Free Radicals

J. Downey, S. Critz, M. Cohen, 2000, Circulation research.

Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS.

J. Downey, M. Kelm, R. Schulz, 2006, American journal of physiology. Heart and circulatory physiology.

Mitochondrial ROS generation following acetylcholine-induced EGF receptor transactivation requires metalloproteinase cleavage of proHB-EGF.

J. Downey, T. Krieg, Q. Qin, 2004, Journal of molecular and cellular cardiology.

Mitochondrial KATP channels in preconditioning

Michael V. Cohen, J. Downey, O. Oldenburg, 2003 .

Focus on the Mitochondrion Mitochondrial K ATP channels in preconditioning

Michael V. Cohen, J. Downey, O. Oldenburg, 2003 .

ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases.

J. Downey, T. Krieg, Q. Qin, 2002, American journal of physiology. Heart and circulatory physiology.

Circulating blood cells and extracellular vesicles in acute cardioprotection.

J. Downey, K. Preissner, P. Ferdinandy, 2018, Cardiovascular research.

The pH Hypothesis of Postconditioning: Staccato Reperfusion Reintroduces Oxygen and Perpetuates Myocardial Acidosis

J. Downey, Xi-ming Yang, M. Cohen, 2007, Circulation.

Protein Kinase C- ξ is Responsible for the Protection of Preconditioning in Rabbit Cardiomyocytes

Michael V. Cohen, J. Downey, D. Mochly‐Rosen, 1999 .

The impact of irreproducibility and competing protection from P2Y12 antagonists on the discovery of cardioprotective interventions

Michael V. Cohen, J. Downey, M. Cohen, 2017, Basic Research in Cardiology.

Postconditioning’s protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3–kinase and guanylyl cyclase activation

J. Downey, S. Philipp, Xi-ming Yang, 2004, Basic Research in Cardiology.

Correlative atlas of adult cardiac disorders : noninvasive diagnostic techniques

M. Cohen, 1980 .

Why do we still not have cardioprotective drugs?

Michael V. Cohen, J. Downey, M. Cohen, 2009, Circulation journal : official journal of the Japanese Circulation Society.

Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y12 receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function

J. Downey, D. Alvarez, J. Audia, 2018, Basic Research in Cardiology.

The Role of Pyroptosis in Ischemic and Reperfusion Injury of the Heart

J. Downey, S. Popov, V. Ryabov, 2021, Journal of cardiovascular pharmacology and therapeutics.

Coronary Occlusions uring Early Reperfusion Protect Rabbit earts by Targeting Cell Signaling Pathways

T. Krieg, I. Yang, Lin Cui, 2016 .

Signalling pathways and mechanisms of protection in pre‐ and postconditioning: historical perspective and lessons for the future

Michael V. Cohen, J. Downey, M. Cohen, 2015, British journal of pharmacology.

Innate immunity as a target for acute cardioprotection.

J. Downey, K. Preissner, A. Abbate, 2019, Cardiovascular research.

Acidosis, oxygen, and interference with mitochondrial permeability transition pore formation in the early minutes of reperfusion are critical to postconditioning’s success

Michael V. Cohen, J. Downey, Xi-ming Yang, 2008, Basic Research in Cardiology.

cGMP signalling in pre- and post-conditioning: the role of mitochondria.

Michael V. Cohen, J. Downey, S. Pierre, 2008, Cardiovascular research.

Ischemic postconditioning: from receptor to end-effector.

Michael V. Cohen, J. Downey, M. Cohen, 2011, Antioxidants & redox signaling.

P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts.

Michael V. Cohen, J. Downey, G. Grover, 2003, Journal of molecular and cellular cardiology.

C-Reactive Protein: The Harbinger of Cardiovascular Diseases

S. Iskandar, Nader Z. Elgharib, M. Cohen, 2008, Southern medical journal.

AMP 579 Reduces Contracture and Limits Infarction in Rabbit Heart by Activating Adenosine A2 Receptors

J. Downey, Zhelong Xu, M. Cohen, 2001, Journal of cardiovascular pharmacology.

Pathophysiology of Myocardial Reperfusion Injury

Michael V. Cohen, J. Downey, M. Cohen, 2012 .

Nitric oxide is a preconditioning mimetic and cardioprotectant and is the basis of many available infarct-sparing strategies.

Michael V. Cohen, J. Downey, Xi-ming Yang, 2006, Cardiovascular research.

Low Rate of Treatment of Hypercholesterolemia by Cardiologists in Patients With Suspected and Proven Coronary Artery Disease

R. Adelson, B. Levine, M. Cohen, 1991, Circulation.

VENOUS LEVEL COLLATERALS IN THE CORONARY SYSTEM

Michael V. Cohen, J. Downey, M. Cohen, 1992 .

Lethal Caspase-1/4-Dependent Injury Occurs in the First Minutes of Coronary Reperfusion and Requires Calpain Activity

J. Downey, Sarah L Sayner, J. Audia, 2023, International journal of molecular sciences.

Remote Ischemic Conditioning: more explanations and more expectations

J. Downey, E. Iliodromitis, M. Cohen, 2022, Basic Research in Cardiology.

Is It Time to Translate Ischemic Preconditioning’s Mechanism of Cardioprotection into Clinical Practice?

Michael V. Cohen, J. Downey, M. Cohen, 2011, Journal of cardiovascular pharmacology and therapeutics.

Does mild hypothermia protect against reperfusion injury? The debate continues

Michael V. Cohen, J. Downey, R. Tissier, 2011, Basic Research in Cardiology.

Adenosine at reperfusion: a conundrum ready to be resolved.

Michael V. Cohen, J. Downey, M. Cohen, 2009, Journal of the American College of Cardiology.

Adenosine: trigger and mediator of cardioprotection

Michael V. Cohen, J. Downey, M. Cohen, 2008, Basic Research in Cardiology.

Cardioprotection With Adenosine A2 Receptor Activation at Reperfusion

Michael V. Cohen, J. Downey, R. Mueller, 2005, Journal of cardiovascular pharmacology.

Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways.

J. Downey, T. Krieg, Xi-ming Yang, 2004, Journal of the American College of Cardiology.

CGX-1051, A Peptide from Conus Snail Venom, Attenuates Infarction in Rabbit Hearts When Administered at Reperfusion

Michael V. Cohen, J. Downey, Guang S. Liu, 2003, Journal of cardiovascular pharmacology.

Preconditioning Causes Improved Wall Motion as Well as Smaller Infarcts After Transient Coronary Occlusion in Rabbits

J. Downey, M. Cohen, Guang S. Liu, 1991, Circulation.

Myocardial protection with mild hypothermia.

J. Downey, B. Ghaleh, A. Berdeaux, 2012, Cardiovascular research.

Making the heart resistant to infarction: how can we further decrease infarct size?

Michael V. Cohen, J. Downey, T. Krieg, 2008, Frontiers in bioscience : a journal and virtual library.

Combined Cardioprotectant and Antithrombotic Actions of Platelet P2Y12 Receptor Antagonists in Acute Coronary Syndrome

Michael V. Cohen, J. Downey, M. Cohen, 2014, Journal of cardiovascular pharmacology and therapeutics.

Platelet P2Y12 Blockers Confer Direct Postconditioning-Like Protection in Reperfused Rabbit Hearts

Michael V. Cohen, J. Downey, Yongge Liu, 2013, Journal of cardiovascular pharmacology and therapeutics.

Acetylcholine, Bradykinin, Opioids, and Phenylephrine, but not Adenosine, Trigger Preconditioning by Generating Free Radicals and Opening Mitochondrial KATP Channels

J. Downey, G. Heusch, Xi-ming Yang, 2001, Circulation research.

Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt.

J. Downey, V. Solodushko, M. Cohen, 2006, American journal of physiology. Heart and circulatory physiology.

Signal Transduction in Ischemic Preconditioning:

J. Downey, C. Baines, M. Cohen, 1999, Journal of cardiovascular electrophysiology.

Exogenous NO triggers preconditioning via a cGMP- and mitoKATP-dependent mechanism.

J. Downey, T. Lincoln, S. Critz, 2004, American journal of physiology. Heart and circulatory physiology.

Cardioprotection by mild hypothermia during ischemia involves preservation of ERK activity

Michael V. Cohen, J. Downey, Xiulan Yang, 2011, Basic Research in Cardiology.

SB 203580, an inhibitor of p38 MAPK, abolishes infarct-limiting effect of ischemic preconditioning in isolated rabbit hearts

J. Downey, S. Critz, A. Nakano, 2000, Basic Research in Cardiology.

M itochondrial K channels : role in cardioprotectionATP

J. Downey, D. Yellon, O. Oldenburg, 2002 .

A2b adenosine receptors can change their spots

J. Downey, Xiulan Yang, M. Cohen, 2010, British journal of pharmacology.

AMP579 is revealed to be a potent A2b-adenosine receptor agonist in human 293 cells and rabbit hearts

J. Downey, T. Krieg, Xiulan Yang, 2009, Basic Research in Cardiology.

Infarct limitation by a protein kinase G activator at reperfusion in rabbit hearts is dependent on sensitizing the heart to A2b agonists by protein kinase C.

J. Downey, A. Kuno, Yanping Liu, 2008, American journal of physiology. Heart and circulatory physiology.

Reducing infarct size in the setting of acute myocardial infarction.

Michael V. Cohen, J. Downey, M. Cohen, 2006, Progress in cardiovascular diseases.

We think we see a pattern emerging here.

Michael V. Cohen, J. Downey, M. Cohen, 2005, Circulation.

Bypassing big pharma.

Michael V. Cohen, J. Downey, M. Cohen, 2007, Circulation.

Xanthine oxidase contributes to preconditioning's preservation of left ventricular developed pressure in isolated rat heart: developed pressure may not be an appropriate end-point for studies of preconditioning

Michael V. Cohen, J. Downey, C. Morales, 2002, Basic Research in Cardiology.

Myocardial hypothermia preserves mitochondrial and post-ischemic regional left ventricular functions in rabbits

Michael V. Cohen, J. Downey, J. Dubois-Randé, 2009 .

Animal models for the study of myocardial protection against ischemia

Michael V. Cohen, J. Downey, S. Philipp, 2005 .

Mechanisms of acetylcholine- and bradykinin-induced preconditioning.

Michael V. Cohen, J. Downey, S. Critz, 2005, Vascular pharmacology.

Activation of Akt is essential for acetylcholine to trigger generation of oxygen free radicals.

J. Downey, S. Felix, T. Krieg, 2003, Cardiovascular research.

NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase

J. Downey, S. Felix, T. Krieg, 2006, Basic Research in Cardiology.

Protection From AMP 579 Can Be Added to That From Either Cariporide or Ischemic Preconditioning in Ischemic Rabbit Heart

Michael V. Cohen, J. Downey, Zhe Jiao, 2002, Journal of cardiovascular pharmacology.

Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.

Michael V. Cohen, J. Downey, O. Oldenburg, 2002, Cardiovascular research.

O-linked beta-N-acetylglucosamine: a new piece of the cardioprotection puzzle?

Michael V. Cohen, J. Downey, M. Cohen, 2008, Circulation research.

Mitochondrial K(ATP) channels: role in cardioprotection.

Michael V. Cohen, J. Downey, D. Yellon, 2002, Cardiovascular research.

Differential Response of Large and Small Coronary Arteries to Nitroglycerin and Angiotensin: Autoregulation and Tachyphylaxis

M. Cohen, E. Kirk, M. Cohen, 1973, Circulation research.

Adenosine and Opioid Receptors Do Not Trigger the Cardioprotective Effect of Mild Hypothermia

Michael V. Cohen, J. Downey, B. Ghaleh, 2012, Journal of cardiovascular pharmacology and therapeutics.

A really radical observation

J. Downey, M. Cohen, 2006, Basic Research in Cardiology.

Treatment of orthostatic hypotension.

R. Erbel, A. Kribben, T. Philipp, 2002, Current opinion in pharmacology.

CHAPTER 50 – Ischemic Preconditioning: Description, Mechanism, and Significance

Michael V. Cohen, J. Downey, M. Cohen, 2001 .

A really radical observation--a comment on Penna et al. in Basic Res Cardiol (2006) 101:180-189.

J. Downey, M. Cohen, 2006, Basic research in cardiology.

Preconditioning-mimetics bradykinin and DADLE activate PI3-kinase through divergent pathways.

J. Downey, T. Krieg, S. Philipp, 2007, Journal of molecular and cellular cardiology.

All Preconditioning-Related G Protein-Coupled Receptors Can Be Demonstrated in the Rabbit Cardiomyocyte

J. Downey, T. Krieg, R. Barrington, 2012, Journal of cardiovascular pharmacology and therapeutics.

Two Classes of Anti-Platelet Drugs Reduce Anatomical Infarct Size in Monkey Hearts

J. Downey, Yongge Liu, N. Tandon, 2013, Cardiovascular Drugs and Therapy.

Mitochondrially targeted Endonuclease III has a powerful anti-infarct effect in an in vivo rat model of myocardial ischemia/reperfusion

J. Downey, G. Wilson, M. Gillespie, 2015, Basic Research in Cardiology.

Unraveling the mysteries of classical preconditioning.

Michael V. Cohen, J. Downey, M. Cohen, 2005, Journal of molecular and cellular cardiology.

Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits

J. Downey, T. Miki, M. Cohen, 1998, Molecular and Cellular Biochemistry.

Preconditioning one myocardial region does not neccessarily precondition the whole rabbit heart

Michael V. Cohen, J. Downey, A. Nakano, 2002, Basic Research in Cardiology.

Ticagrelor Does Not Protect Isolated Rat Hearts, Thus Clouding Its Proposed Cardioprotective Role Through ENT 1 in Heart Tissue

J. Downey, D. Alvarez, J. Audia, 2019, Journal of cardiovascular pharmacology and therapeutics.

The relative order of mK(ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart.

Michael V. Cohen, J. Downey, S. Critz, 2002, Cardiovascular research.

Letter by Downey and Cohen Regarding Article, "Protective Effects of Ticagrelor on Myocardial Injury After Infarction".

J. Downey, M. Cohen, 2017, Circulation.

Triple Therapy Greatly Increases Myocardial Salvage During Ischemia/Reperfusion in the in situ Rat Heart

J. Downey, Xi-ming Yang, Lin Cui, 2013, Cardiovascular Drugs and Therapy.

Peptide blockers of PKG inhibit ROS generation by acetylcholine and bradykinin in cardiomyocytes but fail to block protection in the whole heart.

J. Downey, T. Krieg, W. Dostmann, 2005, American journal of physiology. Heart and circulatory physiology.

Myocardial Ischemia and Reperfusion

M. Cohen, 1998, Molecular and Cellular Biochemistry.

Left Ventricular Volume and Function During Relief of Cardiac Tamponade in Man

M. Cohen, R. Steingart, R. Grose, 1982, Circulation.

Age-Associated Changes in Diastolic Filling: Doppler E/A Ratio Is Not Associated With Congestive Heart Failure in the Elderly

J. Tobin, C. Derby, M. Cohen, 1994, Southern medical journal.

Modulation of receptor sensitivity: possible therapeutic target?

Michael V. Cohen, J. Downey, M. Cohen, 2009, British journal of pharmacology.

Can global longitudinal strain (GLS) with magnetic resonance prognosticate early cancer therapy-related cardiac dysfunction (CTRCD) in breast cancer patients, a prospective study?

Samuel A. McQuiston, J. Kar, C. Malozzi, 2022, Magnetic resonance imaging.

Cellular Mechanisms in Ischemic Preconditioning: The Role of Adenosine and Protein Kinase C a

J. Downey, Yongge Liu, K. Ytrehus, 1994, Annals of the New York Academy of Sciences.

Role of Adenosine in the Phenomenon of Ischemic Preconditioning

Michael V. Cohen, J. Downey, M. Cohen, 1995 .

Direct left-ventricular global longitudinal strain (GLS) computation with a fully convolutional network.

Samuel A. McQuiston, J. Kar, C. Malozzi, 2021, Journal of biomechanics.

A deep-learning semantic segmentation approach to fully automated MRI-based left-ventricular deformation analysis in cardiotoxicity.

Samuel P McQuiston, C. Malozzi, M. Cohen, 2021, Magnetic resonance imaging.

Comprehensive enhanced methodology of an MRI-based automated left-ventricular chamber quantification algorithm and validation in chemotherapy-related cardiotoxicity

Julia Kar, Michael V Cohen, Samuel A McQuiston, 2020, Journal of medical imaging.

Fully automated and comprehensive MRI-based Left-Ventricular contractility analysis in Post-Chemotherapy breast cancer patients.

Michael V. Cohen, M. Figarola, Samuel P McQuiston, 2020, The British journal of radiology.

Can post-chemotherapy cardiotoxicity be detected in long-term survivors of breast cancer via comprehensive 3D left-ventricular contractility (strain) analysis?

Michael V. Cohen, J. Kar, M. Figarola, 2019, Magnetic resonance imaging.

Introduction to a mechanism for automated myocardium boundary detection with displacement encoding with stimulated echoes (DENSE)

Michael V. Cohen, X. Zhong, J. Kar, 2018, The British journal of radiology.

What is Wrong With Cardiac Conditioning? We May be Shooting at Moving Targets

Michael V. Cohen, J. Downey, N. Dagres, 2015, Journal of cardiovascular pharmacology and therapeutics.

S-T segment voltage during sequential coronary occlusions is an unreliable marker of preconditioning.

Michael V. Cohen, J. Downey, S. Critz, 1999, American journal of physiology. Heart and circulatory physiology.

Fully Automated, MRI-based Left-Ventricular Contractility Analysis in Breast Cancer Patients Following Chemotherapy

Bryant M. Baldwin, J. Kar, M. Figarola, 2019, 2019 IEEE Signal Processing in Medicine and Biology Symposium (SPMB).

Total liquid ventilation provides ultra-fast cardioprotective cooling.

Renaud Tissier, James C Parker, J. Downey, 2007, Journal of the American College of Cardiology.

Oestrogen plays a permissive role in cardioprotection.

J. Downey, M. Cohen, 2008, Cardiovascular research.

Dose-response relationships of the protective and antiprotective effects of acute ethanol exposure in isolated rabbit hearts.

Michael V. Cohen, J. Downey, M. Krenz, 2002, Heart disease.

The Protective and Anti‐Protective Effects of Ethanol in a Myocardial Infarct Model

J. Downey, M. Krenz, M. Cohen, 2002, Annals of the New York Academy of Sciences.

Validation of a deep-learning semantic segmentation approach to fully automate MRI-based left-ventricular deformation analysis in cardiotoxicity.

Samuel A. McQuiston, C. Malozzi, Julia Karr, 2021, The British journal of radiology.

BAY 58-2667, a nitric oxide-independent guanylyl cyclase activator, pharmacologically post-conditions rabbit and rat hearts.

J. Downey, S. Felix, J. Stasch, 2009, European heart journal.

Cardioprotection: spotlight on PKG

J. Downey, M. Cohen, M. Cohen, 2007, British journal of pharmacology.

Evidence for an intracellular localization of the adenosine A2B receptor in rat cardiomyocytes

J. Downey, S. Felix, T. Krieg, 2011, Basic Research in Cardiology.

Influence of left ventricular mass on left ventricular diastolic filling in normotensive morbid obesity.

C. Lambert, M. Cohen, M. Alpert, 1995, American heart journal.

A new animal model of controlled coronary artery occlusion in conscious rabbits.

J. Downey, Yongge Liu, M. Cohen, 1994, Cardiovascular research.

Streptozotocin-induced non-insulin-dependent diabetes protects the heart from infarction.

J. Downey, Yongge Liu, M. Cohen, 1993, Circulation.

Acetylcholine and bradykinin trigger preconditioning in the heart through a pathway that includes Akt and NOS.

J. Downey, T. Krieg, S. Philipp, 2004, American journal of physiology. Heart and circulatory physiology.

Favorable remodeling enhances recovery of regional myocardial function in the weeks after infarction in ischemically preconditioned hearts.

J. Downey, M. Cohen, G. Heusch, 2000, Circulation.

Mitochondria and their role in preconditioning's trigger phase

Michael V. Cohen, J. Downey, T. Krieg, 2003, Basic Research in Cardiology.

A ctivation of Akt is essential for acetylcholine to trigger generation of oxygen free radicals

J. Downey, S. Felix, M. Alexeyev, 2003 .

Rat and rabbit heart infarction: effects of anesthesia, perfusate, risk zone, and method of infarct sizing.

J. Downey, Yongge Liu, M. Cohen, 1994, The American journal of physiology.

Ischemia induced activation of heat shock protein 27 kinases and casein kinase 2 in the preconditioned rabbit heart.

J. Downey, S. Katz, C. Baines, 1999, Biochemistry and cell biology = Biochimie et biologie cellulaire.

The impact of irreproducibility and competing protection from P2Y12 antagonists on the discovery of cardioprotective interventions

J. Downey, M. Cohen, 2017, Basic Research in Cardiology.

Free radicals in the heart: friend or foe?

Michael V. Cohen, J. Downey, M. Cohen, 2008, Expert review of cardiovascular therapy.

Timing and duration of administration are crucial for antiinfarct effect of AMP 579 infused at reperfusion in rabbit heart.

J. Downey, Zhelong Xu, M. Cohen, 2003, Heart disease.

Free-radical scavengers preserve wall motion in the xanthine oxidase-deficient rabbit heart

J. Downey, T. Matsuki, M. Cohen, 1990 .

Protective and anti-protective effects of acute ethanol exposure in myocardial ischemia/reperfusion.

Michael V. Cohen, J. Downey, M. Krenz, 2004, Pathophysiology : the official journal of the International Society for Pathophysiology.

The small chill: mild hypothermia for cardioprotection?

J. Downey, B. Ghaleh, A. Berdeaux, 2010, Cardiovascular research.

Protective and anti-protective effects of acute ethanol exposure have similar thresholds in isolated rabbit hearts

J. Downey, M. Krenz, Xi-ming Yang, 2001 .

Conscious rabbits become tolerant to multiple episodes of ischemic preconditioning.

J. Downey, M. Cohen, X. Yang, 1994, Circulation research.