E. Matthes

发表

Potent inhibitory activity of chimeric oligonucleotides targeting two different sites of human telomerase.

E. Uhlmann, L. Dimitrova, E. Matthes, 2005, Oligonucleotides.

Tamoxifen is a Na(+)-antagonistic inhibitor of Na+/K(+)-transporting ATPase from tumour and normal cells.

K. Repke, E. Matthes, 1994, Journal of enzyme inhibition.

Selective endocytosis of fluorothymidine and azidothymidine coupled to LDL into HIV infected mononuclear cells.

G. Pauli, J. Mankertz, E. Riedel, 1996, Biochimica et biophysica acta.

Alteration of DNA topoisomerase II activity during infection of H9 cells by human immunodeficiency virus type 1 in vitro: a target for potential therapeutic agents.

W. Müller, P. Langen, A. Maidhof, 1990, Antiviral research.

Inhibition of hepatitis B virus production by modified 2',3'-dideoxy-thymidine and 2',3'-dideoxy-5-methylcytidine derivatives. In vitro and in vivo studies.

H. Will, W. Müller, R. Steffen, 1992, Biochemical pharmacology.

Potent inhibition of hepatitis B virus production in vitro by modified pyrimidine nucleosides

H. Will, W. Müller, P. Langen, 1990, Antimicrobial Agents and Chemotherapy.

Synergistic Anti-Human Immunodeficiency Viral (HIV-1) Effect of the Immunomodulator Ampligen (Mismatched Double-Stranded RNA) with Inhibitors of Reverse Transcriptase and HIV-1 Regulatory Proteins

H. Ushijima, W. Müller, J. Muth, 1993 .

Altered histone-DNA interactions in rat liver chromatin containing 5-bromodeoxyuridine-substituted DNA.

R. Lindigkeit, P. Langen, E. Matthes, 1977, Cell differentiation.

Narcissus and Gerardia lectins: Tools for the development of a vaccine against AIDS and a new ELISA to quantify HIV-gp 120

M. Bachmann, W. Müller, H. Schäcke, 1991 .

Real-Time Determination of Telomerase Activity in Cell Extracts Using an Optical Biosensor

F. Scheller, F. Bier, M. Bienert, 2002, Biological chemistry.

Strong Antiviral Activity of the New L-Hydroxycytidine Derivative, L-HYD4FC, In HBV-Infected Human Chimeric UPA/SCID Mice

J. Bierwolf, J. Pollok, T. Volz, 2012, Antiviral therapy.

Cellular Pharmacology of the Anti-Hepatitis B Virus Agent β-l-2′,3′-Didehydro-2′,3′-Dideoxy-N4-Hydroxycytidine: Relevance for Activation in HepG2 Cells

H. Bünger, E. Matthes, 2009, Antimicrobial Agents and Chemotherapy.

Strong and Selective Inhibitors of Hepatitis B Virus Replication among Novel N4-Hydroxy- and 5-Methyl-β-l-Deoxycytidine Analogues

H. Will, H. Sirma, A. Funk, 2007, Antimicrobial Agents and Chemotherapy.

The antiretroviral and cytostatic activity, and metabolism of 3'-azido-2',3'-dideoxythymidine, 3'-fluoro-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly cell type-dependent.

E. De Clercq, J. Balzarini, P. Meeus, 1989, Advances in experimental medicine and biology.

Phosphorylation, anti-HIV activity and cytotoxicity of 3'-fluorothymidine.

P. Langen, H. Rosenthal, D. Scholz, 1988, Biochemical and biophysical research communications.

Inhibition of Human Immunodeficiency Virus‐1 Infection by Human Conglutinin‐like Protein: In vitro Studies

H. Ushijima, W. Müller, M. Gašić, 1992, Japanese journal of cancer research : Gann.

Human immunodeficiency virus: novel enzyme-linked immunoassays for quantitation of envelope glycoprotein 120.

L. Brigido, J. Mills, M. Bachmann, 1991, Journal of virological methods.

Human tissues degrade uridine much less than thymidine. Possible consequence for 5-fluorouracil therapy.

P. Langen, E. Matthes, B. Liermann, 1984, Biochemical pharmacology.

Chemo-enzymatic synthesis of a new type of enantiomerically pure carbocyclic nucleoside analogues with strong inhibitory effects on terminal deoxynucleotidyl transferase.

F. Theil, S. Ballschuh, E. Matthes, 1998, Bioorganic & medicinal chemistry.

Fluorescent focus reduction assay for the screening of antiadenoviral agents.

R. Mentel, U. Wegner, E. Matthes, 1996, Journal of virological methods.

Extremely underwound chromosomal DNA in nucleoids of mouse sarcoma cells.

M. Hartwig, E. Matthes, W. Arnold, 1981, Cancer letters.

Newly synthesized l-enantiomers of 3'-fluoro-modified β-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases α, β, γ, δ, and ε nor HIV-1 reverse transcriptase

U. Hübscher, P. Hafkemeyer, B. Costisella, 1998 .

Comparative inhibition of hepatitis B virus DNA polymerase and cellular DNA polymerases by triphosphates of sugar-modified 5-methyldeoxycytidines and of other nucleoside analogs

H. Meisel, E. Matthes, C. Lehmann, 1991, Antimicrobial Agents and Chemotherapy.

Inhibition of duck hepatitis B virus replication by 2',3'-dideoxy-3'-fluoroguanosine in vitro and in vivo

H. Blum, P. Hafkemeyer, W. Offensperger, 1996, Antimicrobial agents and chemotherapy.

Inhibitory activity of 3'-fluoro-2' deoxythymidine and related nucleoside analogues against adenoviruses in vitro.

M. Kinder, R. Mentel, U. Wegner, 1997, Antiviral research.

Inhibition of hepatitis B virus DNA polymerase by 3′‐fluorothymidine triphosphate and other modified nucleoside triphosphate analogs

H. Meisel, D. Bärwolff, E. Matthes, 1990, Journal of medical virology.

Inhibition of HIV-replication by 3'-fluoro-modified nucleosides with low cytotoxicity.

D. Scholz, E. Matthes, C. Lehmann, 1989, Biochemical and biophysical research communications.

Inhibition of HIV-associated reverse transcriptase by sugar-modified derivatives of thymidine 5′-triphosphate in comparison to cellular DNA polymerases α and β

P. Langen, H. Rosenthal, D. Scholz, 1987 .

Inhibition of HIV-associated reverse transcriptase by sugar-modified derivatives of thymidine 5'-triphosphate in comparison to cellular DNA polymerases alpha and beta.

P. Langen, H. Rosenthal, D. Scholz, 1987, Biochemical and Biophysical Research Communications - BBRC.

3'-Deoxy-3'-fluorothymidinetriphosphate: inhibitor and terminator of DNA synthesis catalysed by DNA polymerase beta, terminal deoxynucleotidyl transferase and DNA polymerase I.

B. Drescher, P. Langen, E. Matthes, 1985, Biomedica biochimica acta.

Inhibition of Hepatitis B Virus DNA Polymerase by Thymidine Triphosphate Analogues in vitro

H. Meisel, E. Matthes, M. Janta-lipinski, 1991 .

Inhibition of adenovirus DNA polymerase by modified nucleoside triphosphate analogs correlate with their antiviral effects on cellular level

L. Gürtler, R. Mentel, U. Wegner, 2000, Medical Microbiology and Immunology.

Human conglutinin-like protein inhibits infection by the human immunodeficiency virus-1 in vitro.

H. Ushijima, W. Müller, S. Poznanović, 1992, Research in Virology.

Avarol restores the altered prostaglandin and leukotriene metabolism in monocytes infected with human immunodeficiency virus type 1.

W. Müller, M. Gašić, H. Schröder, 1991, Virus research.

Inhibition of expression of human immunodeficiency virus-1 in vitro by antibody-targeted liposomes containing antisense RNA to the env region.

L. Leserman, W. Müller, H. Schröder, 1990, The Journal of biological chemistry.

Protein and RNA of human telomerase as targets for modified oligonucleotides.

H. Scheer, E. Matthes, C. Lehmann, 1999, Nucleosides & nucleotides.

Telomerase protein rather than its RNA is the target of phosphorothioate-modified oligonucleotides.

E. Matthes, C. Lehmann, Eckart Matthes, 1999, Nucleic acids research.

Detection of activity of telomerase in tumor cells using fiber optical biosensors.

Frank F Bier, Peter M Schmidt, F. Bier, 2002, Biosensors & bioelectronics.

Biochemical and genetical analysis of AZT-resistant HIV-mutants.

L. Biesert, H. Rübsamen-Waigmann, U. Dietrich, 1991, Behring Institute Mitteilungen.

Potential suitability of Na+/K(+)-transporting ATPase in pre-screens for anti-cancer agents.

E. Nissen, J. Weiland, R. Megges, 1995, Anti-cancer drug design.

Strong Antiviral Activity of the New L-Hydroxycytidine Derivative, L-HYD4FC, In HBV-Infected Human Chimeric UPA/SCID Mice

J. Bierwolf, J. Pollok, T. Volz, 2012, Antiviral therapy.

THE INCORPORATION OF HYDROXYMETHYLDEOXYURIDINE INTO DNA OF EHRLICH ASCITES CARCINOMA CELLS AND SOME OF ITS CONSEQUENCES

P. Langen, D. Bärwolff, E. Matthes, 1979 .