Kelly A George

Factor quinolinone inhibitors disrupt spindles and multiple LSF (TFCP2)-protein interactions in mitosis, including with microtubule-associated proteins

A. Emili, S. Schaus, J. Shah, 2022, PloS one.

Targeting the oncogene LSF with either the small molecule inhibitor FQI1 or siRNA causes mitotic delays with unaligned chromosomes, resulting in cell death or senescence

S. Schaus, J. Shah, C. Pedamallu, 2019, bioRxiv.

Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling

Chao Zhang, Kevan M. Shokat, Prasad V. Jallepalli, 2010, The Journal of cell biology.

Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells.

P. Jallepalli, T. Stearns, K. Uryu, 2009, Developmental cell.

Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication.

S. Mccarroll, P. Jallepalli, A. Koren, 2021, Molecular cell.

LSF small molecule inhibitors phenocopy LSF-targeted siRNAs causing mitotic defects and senescence in cancer cells

S. Schaus, J. Shah, C. Pedamallu, 2019 .

Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells.

P. Jallepalli, T. Stearns, K. Uryu, 2009, Developmental cell.