Hélène Lévaique

发表

Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation.

J. Bignon, D. Borgel, F. Saller, 2020, European journal of medicinal chemistry.

1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation.

A. Paci, J. Bignon, B. Gigant, 2018, Journal of medicinal chemistry.

Pyrrolo-imidazo[1,2-a]pyridine Scaffolds through a Sequential Coupling of N-tosylhydrazones with Imidazopyridines and Reductive Cadogan Annulation, Synthetic Scope, and Application.

J. Bignon, P. Retailleau, M. Alami, 2019, The Journal of organic chemistry.

A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation.

J. Bignon, C. Lenoir, S. Apcher, 2018, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors.

J. Bignon, G. Bollot, S. Apcher, 2022, European journal of medicinal chemistry.

Cytotoxic Prenylated Stilbenes Isolated from Macaranga tanarius.

J. Bignon, J. Wolfender, P. Allard, 2017, Journal of natural products.

Imidazodipyridines via DMAP Catalyzed Domino N−H Carbonylation and 6π‐Electrocyclization: Synthetic Scope and Application

J. Bignon, P. Retailleau, Abderrahman El Bouakher, 2020 .

Biotransformation of natural compounds. Oxido-reduction of Sch-642305 by Aspergillus ochraceus ATCC 1009.

S. Lumyong, P. Retailleau, J. Gallard, 2011, Bioorganic & medicinal chemistry letters.

Palladium-Catalyzed One-Pot Reaction of Hydrazones, Dihaloarenes, and Organoboron Reagents: Synthesis and Cytotoxic Activity of 1,1-Diarylethylene Derivatives.

J. Bignon, J. Brion, M. Alami, 2015, The Journal of organic chemistry.

One-Pot Synthesis of 2-Styrylindoles from Ortho-Substituted Chloroenynes.

J. Bignon, J. Dubois, M. Alami, 2018, The Journal of organic chemistry.

Synthesis and Anticancer Properties of Oxazepines Related to Azaisoerianin and IsoCoQuinesSynthesis and Anticancer Properties of Oxazepines Related to Azaisoerianin and IsoCoQuines.

J. Bignon, J. Dubois, M. Alami, 2020, ChemMedChem.

ATP Hydrolysis and Pristinamycin IIA Inhibition of the Staphylococcus aureus Vga(A), a Dual ABC Protein Involved in Streptogramin A Resistance*

O. Chesneau, J. Betton, E. Jacquet, 2008, Journal of Biological Chemistry.

Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4.

J. Bignon, G. Bollot, K. Benihoud, 2018, Journal of medicinal chemistry.

Alkyl-Resorcinol Derivatives as Inhibitors of GDP-Mannose Pyrophosphorylase with Antileishmanial Activities

J. Bignon, M. Litaudon, C. Apel, 2021, Molecules.

N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents.

J. Bignon, J. Dubois, M. Alami, 2019, European journal of medicinal chemistry.

Synthesis and biological evaluation of C-13' substituted 7'-homo-anhydrovinblastine derivatives.

J. Bignon, F. Roussi, S. Thoret, 2015, Bioorganic & medicinal chemistry letters.

Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency.

P. Colas, P. Bonnet, J. Bignon, 2020, European journal of medicinal chemistry.

Pipestelides A-C: cyclodepsipeptides from the Pacific marine sponge Pipestela candelabra.

T. Cresteil, J. Sorres, C. Debitus, 2012, Journal of natural products.

Isolation, structure elucidation and biological activity of metabolites from Sch-642305-producing endophytic fungus Phomopsis sp. CMU-LMA.

S. Lumyong, P. Retailleau, J. Ouazzani, 2011, Phytochemistry.