Meng Wang

发表

Platinum(IV) complexes conjugated with chalcone analogs as dual targeting anticancer agents: In vitro and in vivo studies.

Lumei Dai, Hengshan Wang, Zhikun Liu, 2020, Bioorganic chemistry.

Synthesis and biological evaluation of novel millepachine derivative containing aminophosphonate ester species as novel anti-tubulin agents.

Chungu Wang, T. Ma, Hengshan Wang, 2019, Bioorganic chemistry.

Targeting RAS-RAF pathway significantly improves antitumor activity of Rigosertib-derived platinum(IV) complexes and overcomes cisplatin resistance.

S. Gou, Lei Fang, Hengshan Wang, 2020, European journal of medicinal chemistry.

Synthesis, mechanisms of action, and toxicity of novel aminophosphonates derivatives conjugated irinotecan in vitro and in vivo as potent antitumor agents.

Ri-zhen Huang, Haijiang Zhang, Hengshan Wang, 2020, European journal of medicinal chemistry.

Dual-target platinum(IV) complexes exhibit antiproliferative activity through DNA damage and induce ER-stress-mediated apoptosis in A549 cells.

Hengshan Wang, Zhikun Liu, Xiao-chao Huang, 2021, Bioorganic chemistry.

Dual-targeting antitumor conjugates derived from platinum(IV) prodrugs and microtubule inhibitor CA-4 significantly exhibited potent ability to overcome cisplatin resistance.

Chungu Wang, S. Gou, Hengshan Wang, 2019, Bioorganic chemistry.

Novel Indole-Chalcone Derivative-Ligated Platinum(IV) Prodrugs Attenuate Cisplatin Resistance in Lung Cancer through ROS/ER Stress and Mitochondrial Dysfunction.

Ri-zhen Huang, Zhikun Liu, Xiao-chao Huang, 2023, Journal of medicinal chemistry.

Platinum-Based Modification of Styrylbenzylsulfones as Multifunctional Antitumor Agents: Targeting RAS-RAF Pathway, Enhancing Antitumor Activity and Overcoming Multidrug Resistance.

S. Gou, Lei Fang, Hengshan Wang, 2019, Journal of medicinal chemistry.

Ligustrazine-Derived Chalcones-Modified Platinum(IV) Complexes Intervene in Cisplatin Resistance in Pancreatic Cancer through Ferroptosis and Apoptosis.

Zhikun Liu, Xiao-chao Huang, Meng Wang, 2023, Journal of medicinal chemistry.

Dual-targeting tumor cells hybrids derived from Pt(IV) species and NF-κB inhibitors enables cancer therapy through mitochondrial dysfunction and ER stress and overcomes cisplatin resistance.

Zhikun Liu, Xiao-chao Huang, Meng Wang, 2023, European journal of medicinal chemistry.