C. Dorn

发表

Cephalosporin antibiotics can be modified to inhibit human leukocyte elastase

K. R. Thompson, W. Hagmann, A. Maycock, 1986, Nature.

Expression and characterization of the chemokine receptor CCR2B from rhesus monkey.

M. Struthers, W. Hanlon, J. Demartino, 2003, Biochemical pharmacology.

A new fluorogenic substrate for plasmin.

M. Zimmerman, C. Dorn, P. A. Pierzchala, 1979, The Biochemical journal.

Formation of polymorphonuclear leukocyte elastase: alpha 1 proteinase inhibitor complex and A alpha (1-21) fibrinopeptide in human blood stimulated with the calcium ionophore A23187. A model to characterize inhibitors of polymorphonuclear leukocyte elastase.

W. Hanlon, R. Mumford, J. Humes, 1995, Biochemical pharmacology.

The Discovery and Biologic Properties of Cephalosporin‐Based Inhibitors of PMN Elastase

M. Navia, W. Hanlon, E. Opas, 1991, Annals of the New York Academy of Sciences.

Pharmacological profile of the substituted beta‐lactam L‐659,286: A member of a new class of human PMN elastase inhibitors

L. Schaeffer, W. Hagmann, A. Maycock, 1989, Journal of cellular biochemistry.

Proteoglycan-degrading activity of human stromelysin-1 and leukocyte elastase in rabbit joints. Quantitation of proteoglycan and a stromelysin-induced HABR fragment of aggrecan in synovial fluid and cartilage.

W. Hagmann, J. Hale, R. Mumford, 1996, Connective tissue research.

1,4-Diacylpiperazine-2-(S)-[(N-aminoalkyl)carboxamides] as novel, potent substance P receptor antagonists.

C. Strader, W. Greenlee, M. Maccoss, 1993 .

Synthesis of 25-fluorovitamin D3

H. Jones, S. Yang, C. Dorn, 1977 .

Mechanism of inhibition of human leucocyte elastase by monocyclic beta-lactams.

M. Maccoss, W. Hagmann, R. Chabin, 1993, Biochemistry.

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution.

E. Fluder, M. Navia, T. Lin, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters.

J. W. Butcher, J. Doherty, P. Barker, 1990, Journal of medicinal chemistry.

Bioactive carbohydrate derivatives

D. Ebel, R. Fecher, T. Shen, 1972 .

Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs.

J. Metzger, M. Maccoss, D. Macintyre, 2000, Journal of medicinal chemistry.

Orally active beta-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones.

W. Hagmann, J. Hale, S. K. Shah, 1992, Journal of medicinal chemistry.

Specificity, stability, and potency of monocyclic .beta.-lactam inhibitors of human leukocyte elastase

W. M. Westler, R. Chabin, A. Maycock, 1992 .

Anti‐inflammatory–Antirheumatic Drugs

B. Hinz, K. Brune, T. Shen, 2000 .

Direct fluorescent assay of urokinase and plasminogen activators of normal and malignant cells: kinetics and inhibitor profiles.

R. Goldfarb, J. Quigley, W. Troll, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis and immunoadjuvant activity of 2-acetamido-1,5-anhydro-2-deoxy-3-O-[(R)-2-propanoyl-l-alanyl-d-isoglutamine]-d-glucitol (“1-deoxymuramoyl dipeptide”) and its 6-(2-behenoyloxyisobutyrate)☆

P. Durette, T. Shen, A. Friedman, 1982 .

Novel nucleophilic substitution of alkyl bromo-2(1H)-pyridones

H. Jones, T. Shen, B. Witzel, 1985 .

Antagonists of the human CCR5 receptor as anti-HIV-1 agents. part 1: discovery and initial structure-activity relationships for 1 -amino-2-phenyl-4-(piperidin-1-yl)butanes.

E A Emini, D. Hazuda, W. Schleif, 2001, Bioorganic & medicinal chemistry letters.

Proteinase inhibitors. I. Inhibitors of elastase.

E. Yurewicz, S. S. Yang, H. Jones, 1977, Journal of medicinal chemistry.

Synthesis of 24-dehydrocholecalciferol

H. Jones, S. Yang, C. Dorn, 1980, Steroids.

Steroids. IX. Synthesis of some thiazolosteroids.

N. Doorenbos, C. Dorn, 1962, Journal of Pharmacy and Science.

Steroids XXIII. Synthesis of Some Ring A-Fused Heterocyclic Steroids

N. Doorenbos, C. Dorn, 1965 .

Synthesis and immunoadjuvant activities of 2-acetamido-5-O-acetyl-6-O-acyl-2-deoxy-3-O-[(R)-2-propionyl-L-alanyl-D- isoglutamine]-D-glucofuranoses as potential prodrug forms of 6-O-Acyl Derivatives of N-acetylmuramyl dipeptide.

P. Durette, A. Schlabach, A. Friedman, 1982, Journal of medicinal chemistry.

Orally active beta-lactam inhibitors of human leukocyte elastase. 2. Effect of C-4 substitution.

W. Hagmann, A. Maycock, S. K. Shah, 1993, Journal of medicinal chemistry.

Synthesis and acylation of 2-nitro-11H-dibenzo[b,e][1,4]dioxepin

J. Springer, W. Hagmann, C. Dorn, 1986 .

Synthesis and Acylation of 2-Nitro-11H-dibenzo(b,e)(1,4)dioxepine.

J. Springer, W. Hagmann, C. Dorn, 1987 .

Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase.

K. R. Thompson, W. Hagmann, J. Doherty, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Crystallization of human neutrophil elastase.

M. Navia, T. Lin, J. Springer, 1987, Journal of Biological Chemistry.