Peter Chiba

发表

Similarity based SAR (SIBAR) as tool for early ADME profiling

Stephan Kopp, Gerhard F. Ecker, Christian Th. Klein, 2002, J. Comput. Aided Mol. Des..

2D- and 3D-QSAR studies of a series of benzopyranes and benzopyrano[3,4b][1,4]-oxazines as inhibitors of the multidrug transporter P-glycoprotein

Gerhard F. Ecker, Peter Chiba, Manuel Pastor, 2013, Journal of Computer-Aided Molecular Design.

Exhaustive Sampling of Docking Poses Reveals Binding Hypotheses for Propafenone Type Inhibitors of P-Glycoprotein

Gerhard F. Ecker, Peter Chiba, Freya Klepsch, 2011, PLoS Comput. Biol..

MCASE study of the multidrug resistance reversal activity of propafenone analogs

Hao Zhu, Gerhard F. Ecker, Gilles Klopman, 2003, J. Comput. Aided Mol. Des..

Artificial Neural Networks in Drug Design 11: Influence of Learning Rate and Momentum Factor on the Predictive Ability

Gerhard F. Ecker, Peter Chiba, D. Kaiser, 2000 .

Similarity‐Based Descriptors (SIBAR) as Tool for QSAR Studies on P‐Glycoprotein Inhibitors: Influence of the Reference Set

Barbara Zdrazil, Stephan Kopp, Gerhard F. Ecker, 2007 .

Computational models for prediction of interactions with ABC-transporters.

Gerhard F. Ecker, Peter Chiba, Thomas Stockner, 2008, Drug discovery today.

Studies on propafenone-type modulators of multidrug resistance VI. Synthesis and pharmacological activity of compounds with varied spacer length between the central aromatic ring and the nitrogen atom

Gerhard F. Ecker, Peter Chiba, Danilo Annibali, 1998 .

Development of modulators of multidrug resistance: A pharmacoinformatic approach

Gerhard F. Ecker, Peter Chiba, 2004 .

Data‐driven homology modelling of P‐glycoprotein in the ATP‐bound state indicates flexibility of the transmembrane domains

Alexandre M J J Bonvin, Peter Chiba, Sjoerd J de Vries, 2009, The FEBS journal.

Using structural and mechanistic information to design novel inhibitors/substrates of P-glycoprotein.

Markus Müller, Peter Chiba, Thomas Stockner, 2010, Current topics in medicinal chemistry.

Studies on Propafenone‐type Modulators of Multidrug‐Resistance IV : Synthesis and Pharmacological Activity of 5‐Hydroxy and 5‐Benzyloxy Derivatives

Peter Chiba, Elisabeth Richter, Walter Jäger, 1997, Archiv der Pharmazie.

P-Glycoprotein Substrate Binding Domains Are Located at the Transmembrane Domain/Transmembrane Domain Interfaces: A Combined Photoaffinity Labeling-Protein Homology Modeling Approach

Stephan Kopp, Peter Chiba, Andreas Rizzi, 2005, Molecular Pharmacology.

Synthesis and in vitro multidrug resistance modulating activity of a series of dihydrobenzopyrans and tetrahydroquinolines.

Gerhard F. Ecker, Peter Chiba, Christian Wolf, 1999, Journal of medicinal chemistry.

Identification of ligand-binding regions of P-glycoprotein by activated-pharmacophore photoaffinity labeling and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry.

Stephan Kopp, Wolfgang Holzer, Peter Chiba, 2002, Molecular pharmacology.

Multispecificity of Drug Transporters: Probing Inhibitor Selectivity for the Human Drug Efflux Transporters ABCB1 and ABCG2

Stephan Kopp, Peter Chiba, Gerhard F Ecker, 2007, ChemMedChem.

Self-organizing maps for identification of new inhibitors of P-glycoprotein.

Johann Gasteiger, Stephan Kopp, Dominik Kaiser, 2007, Journal of medicinal chemistry.

Studies on Propafenone-Type Modulators of Multidrug Resistance. Part 8. Synthesis and Pharmacological Activity of Indanone Analogues.

Gerhard F. Ecker, Peter Chiba, Elisabeth Richter, 1998 .

Molecular Dissection of Dual Pseudosymmetric Solute Translocation Pathways in Human P-Glycoprotein

Zahida Parveen, Peter Chiba, Thomas Stockner, 2011, Molecular Pharmacology.

Role of transmembrane domain/transmembrane domain interfaces of P-glycoprotein (ABCB1) in solute transport. Convergent information from photoaffinity labeling, site directed mutagenesis and in silico importance prediction.

Olivier Lichtarge, Stephan Kopp, Peter Chiba, 2006, Current medicinal chemistry.

Catalytic cycle of ATP hydrolysis by P-glycoprotein: evidence for formation of the E.S reaction intermediate with ATP-gamma-S, a nonhydrolyzable analogue of ATP.

Stephan Kopp, In-Wha Kim, Peter Chiba, 2007, Biochemistry.

Studies on Propafenone‐type Modulators of Multidrug Resistance III: Variations on the Nitrogen

Gerhard F. Ecker, Peter Chiba, Emiliano Giovagnoni, 1997 .

A Pilot Study to Assess the Efficacy of Tariquidar to Inhibit P-glycoprotein at the Human Blood–Brain Barrier with (R)-11C-Verapamil and PET

Stephan Kopp, Peter Chiba, Wolfgang Löscher, 2009, Journal of Nuclear Medicine.