Karl J Harber

Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses In Vitro Without Altering Inflammatory Disease Outcomes

H. D. de Vries, M. D. de Winther, A. Zawistowska-Deniziak, 2021, Frontiers in Immunology.

Let’s Enter the Wonderful World of Immunometabolites

Kyra E. de Goede, J. Bossche, Karl J Harber, 2019, Trends in Endocrinology & Metabolism.

Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

H. D. de Vries, M. van Weeghel, M. D. de Winther, 2020, Metabolites.

d-2-Hydroxyglutarate is an anti-inflammatory immunometabolite that accumulates in macrophages after TLR4 activation.

M. van Weeghel, E. Struys, M. D. de Winther, 2022, Biochimica et biophysica acta. Molecular basis of disease.

Itaconate promotes a wound resolving phenotype in pro-inflammatory macrophages

G. van den Bogaart, S. Maassen, J. van den Bossche, 2022, Redox biology.

Myeloid-Specific Acly Deletion Alters Macrophage Phenotype In Vitro and In Vivo without Affecting Tumor Growth

Y. van Kooyk, M. D. de Winther, Sjoerd T. T. Schetters, 2021, Cancers.

An HLA-A*11:01-Binding Neoantigen from Mutated NPM1 as Target for TCR Gene Therapy in AML

R. Hagedoorn, M. Heemskerk, M. Griffioen, 2021, Cancers.

Going -omics to identify novel therapeutic targets for cardiovascular disease

S. Verberk, J. van den Bossche, Karl J Harber, 2019, EBioMedicine.