K. Nielsen

Protein expression changes in a cell system of beta-cell maturation reflect an acquired sensitivity to IL-1β

J. Nerup, P. Roepstorff, M. Larsen, 2003, Diabetologia.

Interferon-gamma induces interleukin-1 converting enzyme expression in pancreatic islets by an interferon regulatory factor-1-dependent mechanism.

F. Pociot, J. Nerup, T. Mandrup-Poulsen, 2000, The Journal of clinical endocrinology and metabolism.

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.

P. Serup, T. Mandrup-Poulsen, C. Bonny, 2000, Diabetes.

Beta-cell maturation leads to in vitro sensitivity to cytotoxins.

O. Madsen, P. Serup, J. Nerup, 1999, Diabetes.

Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.

G. Fantuzzi, D. Eizirik, C. Dinarello, 2000, European cytokine network.

Ciliary neurotrophic factor potentiates the beta-cell inhibitory effect of IL-1beta in rat pancreatic islets associated with increased nitric oxide synthesis and increased expression of inducible nitric oxide synthase.

T. Mandrup-Poulsen, C. Larsen, H. Andersen, 1998, Diabetes.

Gene expression profiles during beta cell maturation and after IL-1β exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1β sensitivity

T. Ørntoft, M. Kruhøffer, J. Nerup, 2004, Diabetologia.

Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivity.

M. Kruhøffer, J. Nerup, C. Wollheim, 2004, Diabetologia.