Xiaohan Zhang

发表

GRK2-mediated receptor phosphorylation and Mdm2-mediated β-arrestin2 ubiquitination drive clathrin-mediated endocytosis of G protein-coupled receptors.

Kyeong-Man Kim, M. Zheng, Xiaohan Zhang, 2020, Biochemical and biophysical research communications.

Selectivity of commonly used inhibitors of clathrin-mediated and caveolae-dependent endocytosis of G protein-coupled receptors.

S. Nah, Kyeong-Man Kim, M. Oak, 2015, Biochimica et biophysica acta.

A novel molecular mechanism responsible for phosphorylation-independent desensitization of G protein-coupled receptors exemplified by the dopamine D3 receptor.

Kyeong-Man Kim, M. Zheng, Srijan Acharya, 2020, Biochemical and biophysical research communications.

Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors

Kyeong-Man Kim, C. Min, M. Zheng, 2016, Biomolecules & therapeutics.

PKCβII inhibits the ubiquitination of β‐arrestin2 in an autophosphorylation‐dependent manner

Moo-Yeol Lee, Kyeong-Man Kim, H. Choi, 2015, FEBS letters.

TM7SF1, an important autophagy regulatory protein in mouse podocytes.

Lizhuo Wang, Yao Zhang, Youdi Wang, 2020, Biochemical and biophysical research communications.

Agonist-induced changes in RalA activities allows the prediction of the endocytosis of G protein-coupled receptors.

Kyeong-Man Kim, M. Oak, S. Cheon, 2016, Biochimica et biophysica acta.

Functional Regulation of Dopamine D3 Receptor through Interaction with PICK1

Kyeong-Man Kim, I. Oh, C. Min, 2016, Biomolecules & therapeutics.

Molecular mechanisms involved in epidermal growth factor receptor-mediated inhibition of dopamine D3 receptor signaling.

Kyeong-Man Kim, H. Le, S. Guo, 2018, Biochimica et biophysica acta. Molecular cell research.

The tyrosine phosphorylation of GRK2 is responsible for activated D2R-mediated insulin resistance.

Kyeong-Man Kim, Li Hu, Haiping Liu, 2022, Biochemical and biophysical research communications.

The EGF receptor inhibits the signaling of dopamine D3 receptor through the phosphorylation of GRK2 on tyrosine residues.

Kyeong-Man Kim, Xiaohan Zhang, Xiaowei Zhang, 2017, Biochemical and biophysical research communications.

N-linked Glycosylation on the N-terminus of the dopamine D2 and D3 receptors determines receptor association with specific microdomains in the plasma membrane.

K. Kwon, C. Shin, Kyeong-Man Kim, 2015, Biochimica et biophysica acta.

Roles of Dopamine D2 Receptor Subregions in Interactions with β-Arrestin2

Kyeong-Man Kim, Xiaohan Zhang, Bo-Gil Choi, 2016, Biomolecules & therapeutics.

β-Arrestin2 directly or through GRK2 inhibits PKCβII activation in a ubiquitination-dependent manner.

Kyeong-Man Kim, M. Zheng, Xiaohan Zhang, 2018, Biochimica et biophysica acta. Molecular cell research.

PKCβII activation requires nuclear trafficking for phosphorylation and Mdm2-mediated ubiquitination

Xiaohan Zhang, Ningning Sun, X. Min, 2023, Life Science Alliance.

Mdm2-mediated ubiquitination of β-arrestin2 in the nucleus occurs in a Gβγ- and clathrin-dependent manner.

Kyeong-Man Kim, Xiaohan Zhang, Ningning Sun, 2020, Biochemical pharmacology.

Defective Thyroglobulin: Cell Biology of Disease

P. Arvan, O. Clarke, O. Kabil, 2022, International journal of molecular sciences.

Multifactorial Regulation of G Protein-Coupled Receptor Endocytosis

Kyeong-Man Kim, Xiaohan Zhang, 2017, Biomolecules & therapeutics.

Mdm2-mediated ubiquitination of PKCβII in the nucleus mediates clathrin-mediated endocytic activity.

Kyeong-Man Kim, Srijan Acharya, Xiaohan Zhang, 2019, Biochemical pharmacology.

Thyroid hormone synthesis continues despite biallelic thyroglobulin mutation with cell death

P. Arvan, Cintia E. Citterio, Y. Morishita, 2021, JCI insight.

Sequestration of Gβγ by deubiquitinated arrestins into the nucleus as a novel desensitization mechanism of G protein–coupled receptors

Kyeong-Man Kim, Xiaohan Zhang, Ningning Sun, 2023, Cell Communication and Signaling.

Palmitoylation on the carboxyl terminus tail is required for the selective regulation of dopamine D2 versus D3 receptors.

Kyeong-Man Kim, M. Zheng, H. Le, 2016, Biochimica et biophysica acta.

Cytoplasmic recruitment of Mdm2 as a common characteristic of G protein-coupled receptors that undergo desensitization.

Kyeong-Man Kim, M. Zheng, Xiaohan Zhang, 2020, Biochemical and biophysical research communications.

RalA employs GRK2 and β-arrestins for the filamin A-mediated regulation of trafficking and signaling of dopamine D2 and D3 receptor.

Kyeong-Man Kim, C. Min, M. Zheng, 2016, Biochimica et biophysica acta.

A novel molecular mechanism involved in the crosstalks between homologous and PKC-mediated heterologous regulatory pathway of dopamine D2 receptor.

Kyeong-Man Kim, Xiaohan Zhang, X. Min, 2020, Biochemical pharmacology.

Clathrin-mediated endocytosis is responsible for the lysosomal degradation of dopamine D3 receptor.

Kyeong-Man Kim, M. Zheng, Xiaohan Zhang, 2016, Biochemical and biophysical research communications.

Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases

Sarabjeet Kour Sudan, Xingyue Zeng, Xiaohan Zhang, 2023, International journal of molecular sciences.

Comparative study of the molecular mechanisms underlying the G protein and β‐arrestin‐dependent pathways that lead to ERKs activation upon stimulation by dopamine D2 receptor

Yongkai Cao, Li Hu, Xiaohan Zhang, 2023, The FEBS journal.