J. Sakaki

发表

Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight and modulates gut peptide release—Potential insight into mechanism of action

Shirly Pinto, R. Yoshimoto, T. Roddy, 2013, Obesity.

Effect of a novel bifunctional endothelin receptor antagonist, IRL 3630A, on guinea pig respiratory mechanics.

S. Hori, T. Inui, Y. Sasaki, 2000, European journal of pharmacology.

Discovery of IRL 3461: a novel and potent endothelin antagonist with balanced ETA/ETB affinity.

T. Pitterna, T. Murata, G. Iwasaki, 1998, Bioorganic & medicinal chemistry letters.

IRL 2500: A potent ETB selective endothelin antagonist

Y. Urade, T. Pitterna, T. Inui, 1996 .

Stereoselective synthesis of a novel and bifunctional endothelin antagonist, IRL 3630.

T. Murata, K. Hayakawa, J. Sakaki, 1998, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationship of RXR antagonists based on the diazepinylbenzoic acid structure.

T. Kanazawa, Hidefumi Uchiyama, H. Mitani, 2007, Bioorganic & medicinal chemistry letters.

Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain.

S. Bevan, K. Tanabe, S. Koizumi, 2008, Journal of medicinal chemistry.

Highly enantioselective reduction of acetoacetylated meldrum's acid with fermenting baker's yeast

Tsuyoshi Nakano, Y. Sugita, Masayuki Sato, 1990 .

Overcoming hERG issues for brain-penetrating cathepsin S inhibitors: 2-cyanopyrimidines. Part 2.

S. Bevan, T. Kanazawa, M. Malcangio, 2008, Bioorganic & medicinal chemistry letters.

A SIMPLE METHOD FOR SYNTHESIZING 7-OXO-4-THIA-1-AZABICYCLO [3. 2. 0]-HEPTANE AND ITS 6-METHYL DERIVATIVES FROM ETHYL CYANOACETATE

Takumi Takahashi, C. Kaneko, T. Chiba, 1985 .

A Novel Synthesis of β-Ketothioesters

Satoshi Kobayashi, Masayuki Sato, C. Kaneko, 1990 .

Derivatives of α,α,α′,α′-Tetraaryl-2,2-dimethyl-1,3-dioxolan-4,5-dimethanol (TADDOL) containing nitrogen, sulfur, and phosphorus atoms. New ligands and auxiliaries for enantioselective reactions.

D. Seebach, W. Schweizer, J. Sakaki, 1993 .

Catalytic Enantioselective Hydrosilylation of Aromatic Ketones Using Rhodium Complexes of TADDOL-Derived Cyclic Phosphonites and Phosphites

D. Seebach, W. Schweizer, J. Sakaki, 1993 .

Synthesis of 1, 3-Dioxin-4-ones and Their Use in Synthesis. XVIII. : Synthesis of Azetidin-2-ones from 1, 3-Dioxin-4-ones via 3-Hydroxycarboxamides

Satoshi Kobayashi, Masayuki Sato, J. Sakaki, 1989 .

Use of 1,3-dioxin-4-ones and related compounds in synthesis. Part 39. Enantioselective synthesis of 1,3-dioxin-4-ones having 2,3-dihydroxy- or 2,3,4-trihydroxyalkyl groups at the 6-position: versatile building blocks of polyhydroxylated 4–7 carbon backbones

Y. Sugita, Masayuki Sato, C. Kaneko, 1992 .

1,3‐dioxin‐4‐ones as versatile intermediates for organic synthesis

Masayuki Sato, C. Kaneko, Y. Abe, 1990 .

1,3-Dipolar cycloaddition of di-1-menthyl benzylidenemalonate to (z)n,α-diphenylnitrone: Explanation for diastereoselectivity

N. Watanabe, N. Katagiri, C. Kaneko, 1990 .

Two lactone formation reactions from 1,3-dioxin-4-ones having hydroxyalkyl group at the 6-position: Difference in ring opening and closure☆

Y. Sugita, Masayuki Sato, C. Kaneko, 1991 .

Studies on amino acid derivatives. Part 7. General method for the synthesis of penam and cepham and their substituted derivatives

Masayuki Sato, Takumi Takahashi, C. Kaneko, 1987 .

Novel scaffold for cathepsin K inhibitors.

O. Ohmori, S. Cowan-Jacob, K. Masuya, 2007, Bioorganic & medicinal chemistry letters.

Profiling of trans-azetidine-2,4-dicarboxylic acid at the human metabotropic glutamate receptors mGlu1b, -2, -4a and -5a.

T. Knöpfel, P. Flor, R. Kuhn, 1995, European journal of pharmacology.

4-Amino-2-cyanopyrimidines: novel scaffold for nonpeptidic cathepsin S inhibitors.

T. Kanazawa, H. Hirao, K. Masuya, 2008, Bioorganic & Medicinal Chemistry Letters.

Discovery of selective and nonpeptidic cathepsin S inhibitors.

T. Kanazawa, C. Snell, H. Hirao, 2008, Bioorganic & medicinal chemistry letters.

Studies on amino acid derivatives. IX: Synthesis of chiral penam-3-carboxylic acid and its substituted derivatives

T. Furuya, Satoshi Kobayashi, C. Kaneko, 1989 .

Synthesis of 1,3-dioxin-4-ones having chiral hydroxyalkyl groups at the 6-position by means of baker's yeast reduction and their uses for epc synthesis

Y. Sugita, Masayuki Sato, C. Kaneko, 1991 .

Enantioselective synthesis of (S)- and (R)-6-(2,3-dihydroxypropyl)-1,3-dioxin-4-ones: the versatile building blocks of four- and six-carbon backbones

Y. Sugita, Masayuki Sato, C. Kaneko, 1991 .

Studies on Amino Acid Derivatives. Part 9. Synthesis of Chiral Penam-3-carboxylic Acid and Its Substituted Derivatives.

T. Furuya, Satoshi Kobayashi, C. Kaneko, 1989 .

Synthesis and structure-activity relationship of novel RXR antagonists: orally active anti-diabetic and anti-obesity agents.

T. Kanazawa, Y. Matsumoto, Hidefumi Uchiyama, 2007, Bioorganic & medicinal chemistry letters.