L. Moine

Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design

M. Dorywalska, A. Rajpal, J. Pons, 2016, Molecular Cancer Therapeutics.

Effect of attachment site on stability of cleavable antibody drug conjugates.

M. Dorywalska, A. Rajpal, J. Pons, 2015, Bioconjugate chemistry.

Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy

M. Dorywalska, A. Rajpal, J. Pons, 2015, PloS one.

Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time.

P. Trojer, R. Sims, Shilpi Arora, 2020, ACS medicinal chemistry letters.

Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity

P. Trojer, R. Sims, Shilpi Arora, 2021, The Journal of biological chemistry.

Discovery of a novel Kv7 channel opener as a treatment for epilepsy.

Lei Zhang, R. J. Mather, Christopher R Butler, 2015, Bioorganic & medicinal chemistry letters.