Yuquan Tong

发表

Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA.

Jessica L. Childs-Disney, M. Disney, A. Adibekian, 2022, Journal of the American Chemical Society.

Targeting RNA structures with small molecules

Jessica L. Childs-Disney, M. Disney, R. Batey, 2022, Nature Reviews Drug Discovery.

Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders

Hafeez S Haniff, Jonathan L Chen, Collin A O'Leary, 2020, ACS central science.

Small molecule recognition of disease-relevant RNA structures.

Jessica L. Childs-Disney, M. Disney, Toru Tanaka, 2020, Chemical Society reviews.

Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment.

Jessica L. Childs-Disney, M. Disney, Toru Tanaka, 2021, Journal of the American Chemical Society.

DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor

Jessica L. Childs-Disney, M. Disney, Valerie Cavett, 2022, Proceedings of the National Academy of Sciences.

Bioinformatic Searching for Optimal RNA Targets of Dimeric Compounds Informs Design of a MicroRNA-27a Inhibitor.

M. Disney, R. I. Benhamou, S. Choudhary, 2021, ACS chemical biology.

A blood–brain penetrant RNA-targeted small molecule triggers elimination of r(G4C2)exp in c9ALS/FTD via the nuclear RNA exosome

Jessica L. Childs-Disney, L. Petrucelli, M. Disney, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models

Eric T. Wang, Jonathan L Chen, Jessica L. Childs-Disney, 2021, Science Translational Medicine.

Spatial differentiation of traditional villages using ArcGIS and GeoDa: A case study of Southwest China

Yuquan Tong, Hedan Ma, 2021, Ecol. Informatics.

A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype.

Hafeez S Haniff, M. Disney, Malin Lemurell, 2021, Cell chemical biology.

Systematically Studying the Effect of Small Molecules Interacting with RNA in Cellular and Preclinical Models.

Hafeez S Haniff, M. Disney, Yuquan Tong, 2021, ACS chemical biology.

Programming inactive RNA-binding small molecules into bioactive degraders

Hafeez S Haniff, F. Glorius, M. Disney, 2023, Nature.

Heterobifunctional small molecules to modulate RNA function.

M. Disney, Yuquan Tong, Jessica L. Childs‐Disney, 2024, Trends in pharmacological sciences.

Targeting RNA with small molecules, from RNA structures to precision medicines: IUPHAR review: 40.

M. Disney, Yuquan Tong, Jessica L. Childs‐Disney, 2024, British journal of pharmacology.

Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera

Hafeez S Haniff, M. Disney, A. Adibekian, 2024, Proceedings of the National Academy of Sciences of the United States of America.

Altering the Cleaving Effector in Chimeric Molecules that Target RNA Enhances Cellular Selectivity.

M. Disney, A. Adibekian, D. Abegg, 2023, ACS chemical biology.

Transcriptome-Wide Studies of RNA-Targeted Small Molecules Provide a Simple and Selective r(CUG)exp Degrader in Myotonic Dystrophy

Eric T. Wang, M. Disney, A. Taghavi, 2023, ACS central science.