A. Mete

发表

Palladium catalysed amination of electron deficient halothiophenes

H. Beaton, D. Cheshire, M. Whiting, 2000 .

Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists.

J. Unitt, Bryan E. Roberts, A. Baxter, 2017, ACS medicinal chemistry letters.

The design of a novel series of muscarinic receptor antagonists leading to AZD8683, a potential inhaled treatment for COPD.

N. C. Ray, K. J. Escott, R. Bull, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of substrate-mimicking cytosolic phospholipase A2 inhibitors--reducing the lipophilicity of the arachidonyl chain isostere.

D. Murray, S. Connolly, I. Walters, 2004, Bioorganic & medicinal chemistry letters.

Design of novel and potent cPLA2α inhibitors containing an α-methyl-2-ketothiazole as a metabolically stable serine trap.

D. Murray, M. Bernstein, R. Riley, 2011, Bioorganic & medicinal chemistry letters.

Design and synthesis of a novel and potent series of inhibitors of cytosolic phospholipase A(2) based on a 1,3-disubstituted propan-2-one skeleton.

D. Murray, S. Connolly, I. Walters, 2002, Journal of medicinal chemistry.

Cathepsin C inhibitors: property optimization and identification of a clinical candidate.

R. Austin, J. Breed, J. Debreczeni, 2014, Journal of medicinal chemistry.

The synthesis and chemistry of 3-diazo-piperidin-2-one

S. Matlin, A. Mete, Ian S Hutchinson, 2002 .

Olefination of 3-diazopiperidin-2-one

R. Harrison, A. Mete, Lauren Wilson, 2003 .

The synthesis of 3-diazo-2-nitromethylenepiperidine

S. Matlin, A. Mete, Ian S Hutchinson, 2001 .

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

J. Tainer, E. Getzoff, R. Rosenfeld, 2008, Nature chemical biology.

The relative rate of kill of the MMV Malaria Box compounds provides links to the mode of antimalarial action and highlights scaffolds of medicinal chemistry interest.

G. Biagini, Raman Sharma, Imran Ullah, 2019, The Journal of antimicrobial chemotherapy.

The discovery of AZD9164, a novel muscarinic M3 antagonist.

Keith Bowers, Ken Grime, Helen Edwards, 2011, Bioorganic & medicinal chemistry letters.

The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS).

Glen Andrews, Paul D Leeson, Anders Åberg, 2011, Bioorganic & medicinal chemistry letters.