J. Pawluczyk

发表

Intramolecular [2+2] Cycloaddition of N-Allylcinnamamines and N -Allylcinnamamides by Visible-Light Photocatalysis

A. Mathur, N. Meanwell, Jianqing Li, 2020 .

A prostate-specific antigen (PSA)-activated vinblastine prodrug selectively kills PSA-secreting cells in vivo.

R. Freidinger, Jiunn H. Lin, V. Garsky, 2002, Molecular cancer therapeutics.

1-(((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido) bicyclo(2.2.1)heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl) piperazine (L-368,899): An Orally Bioavailable, Non-Peptide Oxytocin Antagonist with Potential Utility for Managing Preterm Labor.

B. E. Evans, M. Bock, R. Freidinger, 1994 .

Synthesis Optimization, Scale-Up, and Catalyst Screening Efforts toward the MGAT2 Clinical Candidate, BMS-963272

Lidet K. Negash, A. Mathur, R. Lawrence, 2022, Organic Process Research & Development.

Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK.

Michael A. Galella, K. McIntyre, J. Barrish, 2020, ACS medicinal chemistry letters.

Nonpeptide oxytocin antagonists: analogs of L-371,257 with improved potency.

B. E. Evans, M A Jacobson, M. Bock, 1999, Bioorganic & medicinal chemistry letters.

1-(1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4- yl)-4H-3,1-benzoxazin-2(1H)-one (L-371,257): a new, orally bioavailable, non-peptide oxytocin antagonist.

D. Veber, R. Freidinger, D. Reiss, 1995, Journal of medicinal chemistry.

A mild and readily scalable procedure for the N-1-difluoromethylation of ethyl 6-((tert-butyldiphenylsilyl)oxy)-1H-indazole-3-carboxylate and its applications to the N-difluoromethylation of indazole, benzotriazole, imidazole, indole and pyrazole derivatives

A. Mathur, Leon M. Smith, Jianqing Li, 2020, Journal of Fluorine Chemistry.

Route evaluation and development of a practical synthesis of methyl (S)-2-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-7-carboxylate

A. Mathur, Martins S Oderinde, J. Kempson, 2020 .

Applications of microwave-assisted organic synthesis on the multigram scale.

W. Shipe, C. Lindsley, S. Wolkenberg, 2005, Current opinion in drug discovery & development.

Development of the Large-Scale Synthesis of Tetrahydropyran Glycine, a Precursor to the HCV NS5A Inhibitor BMS-986097.

A. Mathur, N. Meanwell, P. Li, 2017, The Journal of organic chemistry.

Photocatalytic Dearomative Intermolecular [2 + 2] Cycloaddition of Heterocycles for Building Molecular Complexity.

Antonio Ramirez, A. Mathur, N. Meanwell, 2020, The Journal of organic chemistry.

Synthesis of Cyclobutane-Fused Tetracyclic Scaffolds via Visible-Light Photocatalysis for Building Molecular Complexity.

Antonio Ramirez, A. Mathur, N. Meanwell, 2020, Journal of the American Chemical Society.

Nanomolar-affinity, non-peptide oxytocin receptor antagonists.

B. E. Evans, K. Rittle, M. Bock, 1993, Journal of medicinal chemistry.

Long-Acting Tumor-Activated Prodrug of a TGFβR Inhibitor.

M. Poss, D. Tortolani, R. Borzilleri, 2021, Journal of medicinal chemistry.

Discovery of (S)-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain.

Alan G. E. Wilson, G. Shankar, J. Macor, 2022, Journal of medicinal chemistry.

Microwave-initiated living free radical polymerization: optimization of the preparative scale synthesis of Rasta resins

C. Lindsley, James J Mulhearn, R. McClain, 2007 .

Development of orally active oxytocin antagonists: studies on 1-(1-[4-[1-(2-methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl]piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and related pyridines.

S Vickers, R. Freidinger, D. Reiss, 1998, Journal of medicinal chemistry.

Development of a Rapid Scale-Up Synthesis of (S)-N-(8-((2-Amino-2,4-dimethylpentyl)oxy)-5H-chromeno[3,4-c]pyridin-2-yl)acetamide, a Potent Adaptor-Associated Kinase 1 Inhibitor

J. Macor, A. Mathur, Jianqing Li, 2022, Organic Process Research & Development.

Conformationally constrained o-tolylpiperazine camphorsulfonamide oxytocin antagonists. Structural modifications that provide high receptor affinity and suggest a bioactive conformation.

D. Veber, R. Freidinger, R. Ball, 1994, Bioorganic & medicinal chemistry.

Orally active, non-peptide oxytocin antagonists

B. E. Evans, D. Veber, M. Bock, 1994 .

Synthesis of 1-(tert-Butyl) 4-Methyl (1R,2S,4R)-2-Methylcyclohexane-1,4-Dicarboxylate from Hagemann's tert-Butyl Ester for an Improved Synthesis of BMS-986251.

A. Mathur, Darpandeep Aulakh, Jianqing Li, 2020, The Journal of organic chemistry.