A. Bourgeois

发表

The Transcription Factor EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse AD Models

Qingli Xiao, E. Duplan, I. Lauritzen, 2020 .

The Transcription Factor EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse Alzheimer’s Disease Models

Qingli Xiao, E. Duplan, I. Lauritzen, 2020, Cells.

Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains

L. Buée, J. Cazareth, I. Lauritzen, 2020, Acta Neuropathologica.

Targeting γ-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models

I. Lauritzen, F. Checler, R. Pardossi-Piquard, 2019, Translational Neurodegeneration.

β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog–Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models

T. Goiran, E. Duplan, Lila Rouland, 2017, Biological Psychiatry.

Does Intraneuronal Accumulation of Carboxyl-terminal Fragments of the Amyloid Precursor Protein Trigger Early Neurotoxicity in Alzheimer's Disease?

I. Lauritzen, F. Checler, R. Pardossi-Piquard, 2019, Current Alzheimer research.

Intraneuronal accumulation of C99 contributes to synaptic alterations, apathy-like behavior, and spatial learning deficits in 3×TgAD and 2×TgAD mice

I. Lauritzen, F. Checler, R. Pardossi-Piquard, 2018, Neurobiology of Aging.

Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology

W. Klein, I. Lauritzen, F. Checler, 2016, Acta Neuropathologica.

The η-secretase-derived APP fragment ηCTF is localized in Golgi, endosomes and extracellular vesicles and contributes to Aβ production

E. Duplan, Wejdane El Manaa, I. Lauritzen, 2023, Cellular and Molecular Life Sciences.

The η-secretase-derived APP fragment ηCTF is localized in Golgi, endosomes and extracellular vesicles and contributes to Aβ production

E. Duplan, Wejdane El Manaa, I. Lauritzen, 2023, Cellular and Molecular Life Sciences.

Transforming Anesthesia Data Into the Observational Medical Outcomes Partnership Common Data Model: Development and Usability Study (Preprint)

B. Tavernier, O. Abou-Arab, Antoine Lamer, 2021 .

Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17

R. Pardossi-Piquard, C. Payré, Joana Justino, 2024, Journal of Biological Chemistry.