S. Ono

发表

Structure-activity study of L-amino acid-based N-type calcium channel blockers.

H. Takimizu, M. Toda, H. Kohno, 2003, Bioorganic & medicinal chemistry.

L-Cysteine based N-type calcium channel blockers: structure-activity relationships of the C-terminal lipophilic moiety, and oral analgesic efficacy in rat pain models.

H. Takimizu, M. Toda, H. Kohno, 2002, Bioorganic & medicinal chemistry letters.

Structure-activity study of L-cysteine-based N-type calcium channel blockers: optimization of N- and C-terminal substituents.

H. Takimizu, M. Toda, H. Kohno, 2002, Bioorganic & medicinal chemistry letters.

Structure-activity study and analgesic efficacy of amino acid derivatives as N-type calcium channel blockers.

H. Takimizu, M. Toda, H. Kohno, 2001, Bioorganic & medicinal chemistry letters.

Synthesis and biological activity of conformationally restricted analogues of milnacipran: (1S, 2R)-1-phenyl-2-[(R)-1-amino-2-propynyl]-N,N- diethylcyclopropanecarboxamide is a novel class of NMDA receptor channel blocker.

S. Shuto, A. Matsuda, H. Imoto, 1998, Journal of medicinal chemistry.

Conformational Restriction by Repulsion between Adjacent Substituents on a Cyclopropane Ring: Design and Enantioselective Synthesis of 1-Phenyl-2-(1-aminoalkyl)-N,N-diethylcyclopropanecarboxamides as Potent NMDA Receptor Antagonists

S. Shuto, A. Matsuda, S. Ono, 1996 .

Synthesis of (+)- and (−)-milnaciprans and their conformationally restricted analogs

S. Shuto, A. Matsuda, S. Ono, 1996 .

Highly stereoselective nucleophilic addition to cyclopropyl carbonyls: The facial selectivity in the cyclopropyl ketones is opposite to that in the corresponding aldehyde

S. Shuto, A. Matsuda, S. Ono, 1996 .

Asymmetric acetalization: a simple method for the synthesis of chiral a-monosubstituted cyclopentanones

M. Nishida, A. Nishida, O. Yonemitsu, 1993 .

Enhanced oral delivery of alendronate by sucrose fatty acids esters in rats and their absorption-enhancing mechanisms.

H. Katsumi, A. Yamamoto, T. Sakane, 2016, International journal of pharmaceutics.

Evaluation of Using Dogs to Predict Fraction of Oral Dose Absorbed in Humans for Poorly Water-Soluble Drugs.

S. Yamashita, K. Sugano, J. Katagi, 2018, Journal of pharmaceutical sciences.

Evaluation of dose-dependent oral absorption of a newly developed drug candidate: In vitro-in vivo correlation

M. Kataoka, S. Yamashita, S. Sakuma, 2016 .

Synthesis and biological activity of conformationally restricted analogs of milnacipran: (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxami de, an efficient noncompetitive N-methyl-D-aspartic acid receptor antagonist.

S. Shuto, T. Noguchi, Y. Ueno, 1996, Journal of medicinal chemistry.

Open channel block of NMDA receptors by conformationally restricted analogs of milnacipran and their protective effect against NMDA‐induced neurotoxicity

S. Shuto, A. Matsuda, T. Noguchi, 1999, Synapse.

(+/-)-(Z)-2-(aminomethyl)-1-phenylcyclopropanecarboxamide derivatives as a new prototype of NMDA receptor antagonists.

S. Shuto, A. Matsuda, R. Tsujita, 1995, Journal of medicinal chemistry.

Quadrantal macular retinal thickness changes in strabismus subjects with abnormal binocular vision development

Tsutomu Yamashita, A. Tabuchi, Mayumi Oka, 2013, Japanese Journal of Ophthalmology.