J. Reeves

发表

The reaction of Grignard reagents with Bunte salts: a thiol-free synthesis of sulfides.

C. Senanayake, Heewon Lee, Z. Han, 2014, Organic letters.

Studies of stereocontrolled allylation reactions for the total synthesis of phorboxazole A.

David R. Williams, M. P. Clark, M. Berliner, 2004, Proceedings of the National Academy of Sciences of the United States of America.

1,4-Dicarbofunctionalization of 4-Fluoroaryl Grignard and Lithium Reagents with Disubstituted Malononitriles.

C. Senanayake, A. Howell, Christian A. Malapit, 2017, The Journal of organic chemistry.

Synthesis of p38 MAP kinase inhibitor BIRB 796 and analogs via copper-mediated N-arylation reaction

Jinhua J. Song, N. Yee, Daniel R Fandrick, 2010 .

Asymmetric methallylation of ketones catalyzed by a highly active organocatalyst 3,3'-F2-BINOL.

Jinhua J. Song, Jun Wang, C. Senanayake, 2013, Organic letters.

Copper catalyzed asymmetric propargylation of aldehydes.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, Journal of the American Chemical Society.

A comparison of 1,4-bis(halomethyl)benzenes as monomers for the modified Gilch route to poly[2-methoxy-5-(2′-ethylhexyloxy)-p-phenylenevinylene]

Angela L. Perkins, Kevin W. Paulisse, B. Tang, 1999 .

Identification of highly efficacious glucocorticoid receptor agonists with a potential for reduced clinical bone side effects.

M. Emmanuel, Alison J Kukulka, G. Nabozny, 2014, Journal of medicinal chemistry.

Zinc catalyzed and mediated propargylations with propargyl boronates.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, Organic letters.

Zinc catalyzed and mediated asymmetric propargylation of trifluoromethyl ketones with a propargyl boronate.

Jinhua J. Song, B. Narayanan, C. Senanayake, 2013, The Journal of organic chemistry.

Achieving synthetic efficiency through new method development

Jinhua J. Song, C. Senanayake, N. Yee, 2008 .

A concise synthesis of butylcycloheptylprodigiosin.

J. Reeves, 2007, Organic letters.

Process Development of the BACE Inhibitors BI 1147560 BS and BI 1181181 MZ

Jinhua J. Song, S. Venkatraman, C. Senanayake, 2022, Organic Process Research & Development.

Organometallic methods for the synthesis and functionalization of azaindoles.

Fabrice Gallou, Jinhua J. Song, C. Senanayake, 2007, Chemical Society reviews.

Direct titanium-mediated conversion of ketones into enamides with ammonia and acetic anhydride.

C. Senanayake, Shengli Ma, Heewon Lee, 2012, Angewandte Chemie.

Development of an Asymmetric Route for Large-Scale Synthesis of a Glucocorticoid Agonist

Jinhua J. Song, Bing-Shiou Yang, C. Senanayake, 2016 .

Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4.

Jinhua J. Song, B. Narayanan, C. Senanayake, 2013, The Journal of organic chemistry.

One-step construction of 2-substituted-4,6-diazaindoles from carboxylic acid derivatives

Jinhua J. Song, C. Senanayake, N. Yee, 2009 .

Practical regioselective bromination of azaindoles and diazaindoles

Jinhua J. Song, C. Senanayake, F. Gallou, 2007 .

Regioselective halogenation of 6-azaindoles : Efficient synthesis of 3-halo-2,3-disubstituted-6-azaindole derivatives

Jinhua J. Song, C. Senanayake, F. Gallou, 2005 .

Cationic triazinium heterocycles by intramolecular NN bond formation

C. Senanayake, Heewon Lee, Z. Han, 2014 .

N-heterocyclic carbene-catalyzed silyl enol ether formation.

Jinhua J. Song, C. Senanayake, N. Yee, 2008, Organic letters.

N-heterocyclic carbene-catalyzed Mukaiyama aldol reactions.

Jinhua J. Song, C. Senanayake, N. Yee, 2007, Organic letters.

Rhodium-Catalyzed Addition of Aryl Boronic Acids to 2,2-Disubstituted Malononitriles.

C. Senanayake, A. Howell, Z. Han, 2017, Angewandte Chemie.

A General Method for Imine Formation Using B(OCH2CF3)3.

C. Senanayake, N. Grinberg, C. Busacca, 2015, Organic letters.

Development of an Enantioselective Hydrogenation Route to (S)-1-(2-(Methylsulfonyl)pyridin-4-yl)propan-1-amine

Jinhua J. Song, Bing-Shiou Yang, C. Senanayake, 2014 .

Direct Titanium‐Mediated Conversion of Ketones into Enamides with Ammonia and Acetic Anhydride.

J. Reeves, 2012 .

A Practical Procedure for Reduction of Primary, Secondary and Tertiary Amides to Amines

C. Senanayake, Heewon Lee, B. Lu, 2013 .

Copper-catalyzed annulation of 2-formylazoles with o-aminoiodoarenes.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, The Journal of organic chemistry.

Transition-metal-mediated cascade reactions: the water-accelerated carboalumination-Claisen rearrangement-carbonyl addition reaction.

P. Wipf, J. Reeves, David L Waller, 2005, The Journal of organic chemistry.

Rhodium-Catalyzed Transnitrilation of Aryl Boronic Acids with Dimethylmalononitrile.

C. Senanayake, A. Howell, Christian A. Malapit, 2016, Angewandte Chemie.

Transnitrilation from Dimethylmalononitrile to Aryl Grignard and Lithium Reagents: A Practical Method for Aryl Nitrile Synthesis.

C. Senanayake, K. Fandrick, Christian A. Malapit, 2015, Journal of the American Chemical Society.

Nickel- or Cobalt-Catalyzed Cross-Coupling of Arylsulfonic Acid Salts with Grignard Reagents

C. Senanayake, A. Howell, Christian A. Malapit, 2015 .

SYNTHESIS AND APPLICATIONS OF A FLUOROUS THP PROTECTIVE GROUP

P. Wipf, J. T. Reeves, J. Reeves, 1999 .

Asymmetric synthesis of active pharmaceutical ingredients.

Jinhua J. Song, C. Senanayake, Vittorio Farina, 2006, Chemical reviews.

Diastereoselective Synthesis of α-Quaternary Aziridine-2-carboxylates via Aza-Corey-Chaykovsky Aziridination of N-tert-Butanesulfinyl Ketimino Esters.

C. Senanayake, Xudong Wei, K. Fandrick, 2015, Organic letters.

N-heterocyclic carbene-catalyzed Mukaiyama aldol reactions.

Jinhua J. Song, C. Senanayake, N. Yee, 2007, Organic letters.

Activation of TMSCN by N-heterocyclic carbenes for facile cyanosilylation of carbonyl compounds.

Jinhua J. Song, C. Senanayake, F. Gallou, 2006, The Journal of organic chemistry.

Synthesis and biological evaluation of structurally highly modified analogues of the antimitotic natural product curacin A.

P. Wipf, B. Day, R. Balachandran, 2002, Journal of medicinal chemistry.

A General Method for Imine Formation Using B(OCH2CF3)3.

C. Senanayake, N. Grinberg, C. Busacca, 2015, Organic letters.

A general copper-BINAP-catalyzed asymmetric propargylation of ketones with propargyl boronates.

C. Senanayake, K. Fandrick, Daniel R Fandrick, 2011, Journal of the American Chemical Society.

Highly diastereoselective zinc-catalyzed propargylation of tert-butanesulfinyl imines.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, Organic letters.

Regioselective allene synthesis and propargylations with propargyl diethanolamine boronates.

Jinhua J. Song, C. Senanayake, N. Yee, 2009, Organic letters.

Carbamoyl anion addition to N-sulfinyl imines: highly diastereoselective synthesis of α-amino amides.

C. Senanayake, K. Fandrick, Shengli Ma, 2013, Journal of the American Chemical Society.

Efficient asymmetric synthesis of P-chiral phosphine oxides via properly designed and activated benzoxazaphosphinine-2-oxide agents.

Jinhua J. Song, C. Senanayake, Shengli Ma, 2013, Journal of the American Chemical Society.

Efficient asymmetric synthesis of structurally diverse P-stereogenic phosphinamides for catalyst design.

Jinhua J. Song, C. Senanayake, N. Yee, 2015, Angewandte Chemie.

Development of a concise, scalable synthesis of a CCR1 antagonist utilizing a continuous flow Curtius rearrangement

Jinhua J. Song, B. Narayanan, Bing-Shiou Yang, 2017 .

Carbamoyl Anion Addition to Azirines.

P. Wipf, C. Senanayake, Michael J Kerner, 2021, Organic letters.

Carbamoyl anion addition to nitrones.

C. Senanayake, Heewon Lee, C. Busacca, 2014, The Journal of organic chemistry.

Copper‐Catalyzed Annulation of 2‐Formylazoles with Aminoiodopyrazoles: Synthesis of New Heterocyclic Ring Systems

C. Senanayake, B. Lu, Zhulin Tan, 2013 .

Copper‐Catalyzed Annulation of 2‐Formylazoles with o‐Aminoiodoarenes.

Jinhua J. Song, C. Senanayake, N. Yee, 2010 .

Design and synthesis of chiral oxathiozinone scaffolds: efficient synthesis of hindered enantiopure sulfinamides and sulfinyl ketimines.

Jinhua J. Song, C. Senanayake, Shengli Ma, 2013, Angewandte Chemie.

Facile entry to an efficient and practical enantioselective synthesis of a polycyclic cholesteryl ester transfer protein inhibitor.

Jinhua J. Song, M. Ostermeier, J. Mack, 2014, Organic letters.

Mild and general zinc-alkoxide-catalyzed allylations of ketones with allyl pinacol boronates.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, Organic letters.

An Enantioselective Synthesis of an 11-β-HSD-1 Inhibitor via an Asymmetric Methallylation Catalyzed by (S)-3,3'-F2-BINOL.

Jiang-Ping Wu, Jun Wang, C. Senanayake, 2016, The Journal of organic chemistry.

Acid mediated deprotection of N-isopropyl tertiary amides

C. Senanayake, C. Busacca, J. Reeves, 2015 .

Triisopropyl borate mediated N-sulfinyl imine formation

C. Senanayake, C. Busacca, I. Volchkov, 2016 .

Total synthesis of phorboxazole A.

David R. Williams, M. P. Clark, M. Berliner, 2003, Angewandte Chemie.

Glycosylation via Cp2ZrCl2/AgClO4-mediated activation of anomeric sulfoxides.

P. Wipf, J. Reeves, 2001, The Journal of organic chemistry.

Direct conversion of primary and secondary carboxylic acids to trifluoromethyl ketones

Jinhua J. Song, C. Senanayake, F. Gallou, 2007 .

Acid-promoted SN1/E1 fragmentation/dimerization of 2-cumylmalonates

Jinhua J. Song, C. Senanayake, N. Yee, 2009 .

Carbolithiation for the generation of cyclooctadienyl anions and tandem electrocyclization/alkylation to functionalized cis-bicyclo[3.3.0]octenes.

David R. Williams, J. Reeves, 2004, Journal of the American Chemical Society.

Room temperature palladium-catalyzed cross coupling of aryltrimethylammonium triflates with aryl Grignard reagents.

Jinhua J. Song, C. Senanayake, N. Yee, 2010, Organic letters.

A computational study of 2,5-dibenzylidenecyclopentanone and 2,6-dibenzylidenecyclohexanone, model compounds for poly(arylidenecycloalkanones)

Kevin W. Paulisse, E. M. Sanford, J. Reeves, 1999 .

N-heterocyclic carbene catalyzed trifluoromethylation of carbonyl compounds.

Jinhua J. Song, C. Senanayake, F. Gallou, 2005, Organic letters.

A general synthesis of substituted formylpyrroles from ketones and 4-formyloxazole.

Jinhua J. Song, C. Senanayake, N. Yee, 2007, Organic letters.

Development of a preparative-scale asymmetric synthesis of (R)-p-tolyl methyl sulfoxide for use in a one-pot synthesis of a drug intermediate containing a trifluoromethyl-substituted alcohol functionality

Jinhua J. Song, C. Senanayake, N. Yee, 2007 .

Start selective and rigidify: The discovery path towards a next generation of EGFR tyrosine kinase inhibitors.

Julian E. Fuchs, P. Ettmayer, A. Baum, 2019, Journal of medicinal chemistry.

Asymmetric Synthesis of Active Pharmaceutical Ingredients

Jinhua J. Song, C. Senanayake, V. Farina, 2006 .

Preparative Synthesis via Continuous Flow of 4,4,5,5-Tetramethyl-2-(3-trimethylsilyl-2-propynyl)-1,3,2-dioxaborolane: A General Propargylation Reagent

Jinhua J. Song, C. Senanayake, J. T. Reeves, 2012 .

Development and Characterization of a Cocrystal as a Viable Solid Form for an Active Pharmaceutical Ingredient

Jinhua J. Song, H. Nar, C. Senanayake, 2013 .

Synthesis and Biological Evaluation of a Focused Mixture Library of Analogues of the Antimitotic Marine Natural Product Curacin A

P. Wipf, K. Giuliano, B. Day, 2000 .

Process safety evaluation of a magnesium : Iodine exchange reaction

Jinhua J. Song, C. Senanayake, N. Yee, 2006 .

A General Copper—BINAP Catalyzed Asymmetric Propargylation of Ketones with Propargyl Boronates.

C. Senanayake, J. T. Reeves, K. Fandrick, 2011 .

Development of a Scalable Synthesis of trans-4-Fluorocyclohexylamine via Directed Hydrogenation

Joyce C. Leung, M. Krawiec, J. Reeves, 2020 .

Chemistry and biology of curacin A.

P. Wipf, B. Day, J. Reeves, 2004, Current pharmaceutical design.

1,3‐Di‐tert‐butylimidazol‐2‐ylidene

Jinhua J. Song, C. Senanayake, N. Yee, 2008 .

Fluorous Tetrahydropyranyl Ether (THP, 2‐Benzenesulfinyl‐3‐heptadecafluorooctyltetrahydropyran)

J. T. Reeves, J. Reeves, 2002 .

Fluorous Alkoxyethyl Ether (AE, [4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11‐Heptadecafluoro‐1‐(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10‐heptadecafluoro‐decyl)‐undecyloxy]‐ethene)

J. T. Reeves, J. Reeves, 2002 .

A formal total synthesis of leucascandrolide A.

P. Wipf, J. T. Reeves, J. Reeves, 2002, Chemical communications.

Development of an Asymmetric Acetate Aldol Reaction with a Trifluoromethyl Ketone

Jinhua J. Song, C. Senanayake, Jinghua Xu, 2007 .

Optimization of an Azaindazole Series of CCR1 Antagonists and Development of a Semicontinuous-Flow Synthesis

F. Buono, Jon C. Lorenz, H. Razavi, 2019, ACS Symposium Series.

Potent and selective CC chemokine receptor 1 antagonists labeled with carbon-13, carbon-14, and tritium.

C. Senanayake, B. Latli, C. Busacca, 2018, Journal of labelled compounds & radiopharmaceuticals.

Practical Synthesis of Terminal Vinyl Fluorides.

Joyce C. Leung, M. Kozlowski, Bangaru Bhaskararao, 2023, The Journal of organic chemistry.

Trifluoromethyl ketones from enolizable carboxylic acids via enediolate trifluoroacetylation/decarboxylation.

Jinhua J. Song, C. Senanayake, N. Yee, 2008, The Journal of organic chemistry.

Studies of the generation and pericyclic behavior of cyclic pentadienyl carbanions. Alkylation reactions as an efficient route to functionalized cis-bicyclo[3.3.0]octenes.

David R Williams, David R. Williams, Mu-Hyun Baik, 2006, Journal of the American Chemical Society.

The reaction of Grignard reagents with Bunte salts: a thiol-free synthesis of sulfides.

C. Senanayake, Heewon Lee, Z. Han, 2014, Organic letters.

Development of a Scalable Synthesis toward a KRAS G12C Inhibitor Building Block Bearing an All-Carbon Quaternary Stereocenter, Part 1: From Discovery Route to Kilogram-Scale Production

Jinhua J. Song, Denis Byrne, Joe Johnson, 2024, Organic Process Research & Development.