M. Dewenter

发表

The Janus face of BNP therapy in chronic heart failure: beneficial effects unmasked by β blockers?

C. Vettel, A. El-Armouche, Matthias Dewenter, 2014, Heart.

Ketone body oxidation increases cardiac endothelial cell proliferation

J. Backs, A. Hotz-Wagenblatt, G. Poschet, 2022, EMBO molecular medicine.

The lipid-droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4

C. Dieterich, P. Most, H. Katus, 2019, Nature Metabolism.

The lipid droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4

C. Dieterich, Tamás Fischer, P. Most, 2019, Nature metabolism.

Calcium Signaling and Transcriptional Regulation in Cardiomyocytes.

H. Katus, J. Backs, Matthias Dewenter, 2017, Circulation research.

Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation.

Eva Wagner, Gordana Vunjak-Novakovic, Malte Tiburcy, 2015, Biomaterials.

Calcium/Calmodulin-Dependent Protein Kinase II Activity Persists During Chronic β-Adrenoceptor Blockade in Experimental and Human Heart Failure.

C. Vettel, T. Wieland, L. Maier, 2017, Circulation. Heart failure.

Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling

R. Brandes, S. Engelhardt, R. Gilsbach, 2022, Frontiers in Physiology.

Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes.

M. Conti, R. Fischmeister, Jin Zhang, 2014, Cardiovascular research.

Function and regulation of serine/threonine phosphatases in the healthy and diseased heart.

D. Dobrev, J. Heijman, A. El-Armouche, 2013, Journal of molecular and cellular cardiology.

Loss of CASK Accelerates Heart Failure Development

Mark E. Anderson, D. Bers, L. Maier, 2021, Circulation research.

A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway

E. Furlong, N. Gretz, M. Völkers, 2017, Nature Medicine.

CaM kinase II regulates cardiac hemoglobin expression through histone phosphorylation upon sympathetic activation

N. Gretz, J. Backs, C. Sticht, 2019, Proceedings of the National Academy of Sciences.

Forebrain corticosteroid receptors promote post-myocardial infarction depression and mortality

T. Schmitz, M. Vogt, P. Gass, 2022, Basic Research in Cardiology.

Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity

L. Maier, J. Backs, D. Dobrev, 2017, Naunyn-Schmiedeberg's Archives of Pharmacology.

CaMKII does not control mitochondrial Ca2+ uptake in cardiac myocytes

J. Backs, Jan Dudek, M. Kohlhaas, 2020, The Journal of physiology.

Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes.

C. Vettel, S. Nattel, L. Maier, 2013, Journal of the American College of Cardiology.

Adaptive versus maladaptive cardiac remodelling in response to sustained β-adrenergic stimulation in a new ‘ISO on/off model’

J. Backs, J. Schultz, Matthias Dewenter, 2021, PloS one.

Chronic isoprenaline/phenylephrine vs. exclusive isoprenaline stimulation in mice: critical contribution of alpha1-adrenoceptors to early cardiac stress responses

C. Vettel, T. Wieland, J. Backs, 2022, Basic Research in Cardiology.

Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control

K. Toischer, W. Zimmermann, O. Müller, 2020, Cardiovascular research.

O-GlcNAcylation of Histone Deacetylase 4 Protects the Diabetic Heart from Failure.

A. Leite-Moreira, A. Sickmann, H. Katus, 2019, Circulation.

The AP-1 transcription factor Fosl-2 drives cardiac fibrosis and arrhythmias under immunofibrotic conditions

D. Razansky, K. Klingel, O. Distler, 2023, Communications Biology.

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction

C. Vettel, T. Wieland, K. Lorenz, 2017, Circulation research.

Integrative Physiology Methods and Results: Pharmacological Inhibition of Phosphodiesterase 2 (bay 60–7550, Bay) Led to a Significant Positive Chronotropic Effect on Top of Maximal Β-adrenoceptor Activation in Healthy Mice. under Pathological Conditions Induced by Chronic Catecholamine Infusions, Ba

C. Vettel, T. Wieland, K. Lorenz, 2022 .

Genetic Loss of Nicotinamide Nucleotide Transhydrogenase Prevents from Cardiometabolic Heart Failure with Preserved Ejection Fraction

J. Backs, M. Pepin, Matthias Dewenter, 2023, bioRxiv.

PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways.

C. Vettel, W. Zimmermann, D. Westermann, 2014, American journal of physiology. Heart and circulatory physiology.

CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2

M. Mayr, C. Vettel, J. Heijman, 2023, Circulation research.

Nitro-fatty acids suppress ischemic ventricular arrhythmias by preserving calcium homeostasis

M. Mollenhauer, F. Nettersheim, B. Freeman, 2020, Scientific Reports.

CaM Kinase II-δ Is Required for Diabetic Hyperglycemia and Retinopathy but Not Nephropathy

H. Hammes, P. Sinn, B. Isermann, 2020, Diabetes.

Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4

C. Vettel, G. Hasenfuss, L. Maier, 2017, Scientific Reports.